{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T16:04:06Z","timestamp":1740153846457,"version":"3.37.3"},"reference-count":40,"publisher":"Korean Society for Preventive Medicine","issue":"6","license":[{"start":{"date-parts":[[2023,10,30]],"date-time":"2023-10-30T00:00:00Z","timestamp":1698624000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["jpmph.org"],"crossmark-restriction":true},"short-container-title":["JPMPH"],"published-print":{"date-parts":[[2023,11,30]]},"abstract":"<jats:p>Objectives: This study analyzed the relationship between parental body mass index (BMI; BMI_p) and hypertension in their adolescent offspring (HTN_a), focusing on the mediating effect of adolescents\u2019 BMI (BMI_a).Methods: Utilizing data from the Korea National Health and Nutrition Examination Survey, including participants aged 12-18, we conducted a mediation analysis while controlling for confounding factors such as age, sex, physical activity, dietary habits, household income quartile, and parents\u2019 alcohol and smoking habits.Results: The study included a total of 5731 participants, of whom 3381 and 5455 participants had data on fathers\u2019 and mothers\u2019 BMI, respectively. For adolescent systolic blood pressure (SBP_a), the father\u2019s BMI (BMI_f) had a significant total effect (\u03b2, 0.23; 95% confidence interval [CI], 0.12 to 0.34) and average controlled mediated effect (ACME) (\u03b2, 0.27; 95% CI, 0.23 to 0.32), but the average direct effect (ADE) was not significant. The mother\u2019s BMI (BMI_m) had a significant total effect (\u03b2, 0.17; 95% CI, 0.09 to 0.25), ACME (\u03b2, 0.25; 95% CI, 0.22 to 0.28) and ADE (\u03b2, -0.08; 95% CI, -0.16 to 0.00). For adolescent diastolic blood pressure, both BMI_f and BMI_m had significant ACMEs (\u03b2, 0.10; 95% CI, 0.08 to 0.12 and \u03b2, 0.09; 95% CI, 0.07 to 0.12, respectively), BMI_m had a significant ADE (\u03b2, -0.09; 95% CI, -0.16 to -0.02) but BMI_f had an insignificant ADE and total effect.Conclusions: The study found that parental BMI had a significant effect on SBP_a, mediated through BMI_a. Therefore, a high BMI in parents could be a risk factor, mediated through BMI_a, for systolic hypertension in adolescents, necessitating appropriate management.<\/jats:p>","DOI":"10.3961\/jpmph.23.289","type":"journal-article","created":{"date-parts":[[2023,11,30]],"date-time":"2023-11-30T05:48:19Z","timestamp":1701323299000},"page":"533-541","update-policy":"https:\/\/doi.org\/10.3961\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Association Between Parental BMI and Offspring\u2019s Blood Pressure by Mediation Analysis: A Study Using Data From the Korean National Health and Nutrition Examination Survey"],"prefix":"10.3961","volume":"56","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2040-389X","authenticated-orcid":true,"given":"Hyowon","family":"Choi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0089-0069","authenticated-orcid":true,"given":"Hunju","family":"Lee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0039-069X","authenticated-orcid":true,"given":"Yeon-Soon","family":"Ahn","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2350","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.5124\/jkma.2020.63.7.404"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1503\/jpn.150268"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehac328"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1016\/s2352-4642(20)30344-8"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1097\/hjh.0000000000001039"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1038\/s41440-019-0229-3"},{"key":"ref7","first-page":"486","volume-title":"High blood pressure in children and adolescents","author":"Riley","year":"2018"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1007\/s11684-018-0640-1"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.3390\/nu11081788"},{"key":"ref10","first-page":"525","volume-title":"Obesity--impact of the family","author":"Hertzler","year":"1981"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1111\/jch.13842"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1123\/jpah.2018-0518"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph182111440"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1093\/ije\/dyi097"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0193978"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1177\/2333794x15625159"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1186\/s12887-021-02807-9"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1161\/01.cir.0000145165.80130.b5"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1056\/nejm199709253371301"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.3390\/nu12103048"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1093\/ije\/dyt228"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1093\/ije\/dyw341"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1136\/bjsports-2020-102955"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.5720\/kjcn.2018.23.4.352"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.1016\/s0140-6736(07)61299-9"},{"key":"ref26","doi-asserted-by":"publisher","DOI":"10.7326\/aitc201712050"},{"key":"ref27","doi-asserted-by":"publisher","DOI":"10.1037\/met0000021"},{"key":"ref28","doi-asserted-by":"publisher","DOI":"10.1177\/0956797613480187"},{"key":"ref29","doi-asserted-by":"publisher","DOI":"10.1093\/ije\/dyw277"},{"key":"ref30","first-page":"171","volume-title":"Development of hypertension in overweight adolescents: a review","author":"Kelly","year":"2015"},{"key":"ref31","first-page":"71","volume-title":"Hypertension in high school students: genetic and environmental factors: the HYGEF study","author":"Bigazzi","year":"2020"},{"key":"ref32","doi-asserted-by":"publisher","DOI":"10.3390\/nu13082821"},{"key":"ref33","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2017.1566"},{"key":"ref34","doi-asserted-by":"publisher","DOI":"10.1016\/j.crvi.2016.11.007"},{"key":"ref35","doi-asserted-by":"publisher","DOI":"10.1111\/j.1753-4887.2004.tb00005.x"},{"key":"ref36","doi-asserted-by":"publisher","DOI":"10.1111\/j.1748-720x.2007.00111.x"},{"key":"ref37","doi-asserted-by":"publisher","DOI":"10.1186\/s12986-019-0357-4"},{"key":"ref38","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.325.7370.917"},{"key":"ref39","doi-asserted-by":"publisher","DOI":"10.1007\/s004670100586"},{"key":"ref40","doi-asserted-by":"publisher","DOI":"10.1016\/s0895-7061(01)02303-2"}],"container-title":["Journal of Preventive Medicine and Public Health"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/jpmph.org\/upload\/pdf\/jpmph-23-289.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/jpmph.org\/journal\/view.php?doi=10.3961\/jpmph.23.289","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/jpmph.org\/upload\/pdf\/jpmph-23-289.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,12,5]],"date-time":"2023-12-05T07:53:17Z","timestamp":1701762797000},"score":1,"resource":{"primary":{"URL":"http:\/\/jpmph.org\/journal\/view.php?doi=10.3961\/jpmph.23.289"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,11,30]]},"references-count":40,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2023,11]]}},"URL":"https:\/\/doi.org\/10.3961\/jpmph.23.289","relation":{},"ISSN":["1975-8375","2233-4521"],"issn-type":[{"type":"print","value":"1975-8375"},{"type":"electronic","value":"2233-4521"}],"subject":[],"published":{"date-parts":[[2023,11,30]]},"assertion":[{"value":"2023-06-21","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-10-16","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-10-30","order":2,"name":"published","label":"Published online","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-11-30","order":3,"name":"published","label":"Print publication","group":{"name":"publication_history","label":"Publication History"}}]}}