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Kato\u2019s modification for bromination of hydroxyheteroarenes with P2O5 and Bu4NBr circumvents the use of POBr3, but it was not suitable in our case because 2,4-dibromopyridine co-distilled with the solvent, 1,2-dichlorobenzene: Y. Kato, S. Okada, K. Tomimoto, and T. Mase, Tetrahedron Lett., 2001, 42, 4849; for halogenation of hydroxyheterocycles, see also: O. Sugimoto, M. Mori, and K. Tanji, Tetrahedron Lett., 1999, 40, 7477.","DOI":"10.1016\/S0040-4039(01)00864-4"},{"key":"10.3987\/COM-07-11170-11","unstructured":"11. AcCl at 130 \u00b0C was not able to reduce 4,4\u2019-dichloro-2,2\u2019-bipyridine N,N-dioxide to 4,4\u2019-dichloro-2,2\u2019-bipyridine (2b)."},{"key":"#cr-split#-10.3987\/COM-07-11170-12.1","unstructured":"12. a) Metal-catalyzed Cross-coupling Reactions, 2nd Ed., ed. by A. de Meijere and F. Diederich, Wiley, Weinheim: 2004. b) N. Zhang, L. Thomas, and B. Wu, J. Org. Chem., 2001, 66, 1500."},{"key":"#cr-split#-10.3987\/COM-07-11170-12.2","doi-asserted-by":"crossref","unstructured":"b) N. Zhang, L. Thomas, and B. Wu, J. Org. Chem., 2001, 66, 1500.","DOI":"10.1021\/jo005682n"},{"key":"#cr-split#-10.3987\/COM-07-11170-13.1","doi-asserted-by":"crossref","unstructured":"a) Y. Yamamoto, T. Tanaka, M. Yagi, and M. Inamoto, Heterocycles, 1996, 42, 189.","DOI":"10.3987\/COM-94-S4-1"},{"key":"#cr-split#-10.3987\/COM-07-11170-13.2","doi-asserted-by":"crossref","unstructured":"b) D. J. C\u00e1rdenas and J.-P. Sauvage, Synlett, 1996, 916.","DOI":"10.1055\/s-1996-5588"},{"key":"#cr-split#-10.3987\/COM-07-11170-13.3","doi-asserted-by":"crossref","unstructured":"c) U. S. Schubert, C.Eschbaumer, and C. H. Weidl, Synlett, 1999, 342.","DOI":"10.1055\/s-1999-2600"},{"key":"10.3987\/COM-07-11170-14","doi-asserted-by":"crossref","unstructured":"14. M. Benaglia, S. Toyota, C. R. Woods, and J. S. Siegel, Tetrahedron Lett., 1997, 38, 4737.","DOI":"10.1016\/S0040-4039(97)01025-3"},{"key":"10.3987\/COM-07-11170-15","unstructured":"15. D. Perrin and W. Armarego, Purification of Laboratory Chemicals; Pergamon Press: Oxford 1998."},{"key":"10.3987\/COM-07-11170-16","doi-asserted-by":"crossref","unstructured":"16. 2-Bromopyridine N-oxide was prepared as in E. Shaw, J. Bernstein, K. Losee, and W. A. Lott, J. Am. Chem. Soc., 1950, 72, 4362. 2-Bromo-4-nitropyridine N-oxide was prepared as in F. Leonard and A. Wajngurt, J. Org. Chem., 1956, 21, 1077.","DOI":"10.1021\/ja01166a008"},{"key":"10.3987\/COM-07-11170-17","unstructured":"17. Prepared as in F. Effenberger, A. Krebs, and P. Willrett, Chem. 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