{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,29]],"date-time":"2026-10-29T03:01:44Z","timestamp":1793242904360,"version":"4.5.0"},"reference-count":47,"publisher":"XMLink","issue":"5","license":[{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0"}],"funder":[{"DOI":"10.13039\/501100003725","name":"National Research Foundation of Korea","doi-asserted-by":"publisher","award":["NRF-2022R1A2C1012522"],"award-info":[{"award-number":["NRF-2022R1A2C1012522"]}],"id":[{"id":"10.13039\/501100003725","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003710","name":"Korea Health Industry Development Institute","doi-asserted-by":"publisher","award":["HI21C1659"],"award-info":[{"award-number":["HI21C1659"]}],"id":[{"id":"10.13039\/501100003710","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100008005","name":"Yonsei University College of Medicine","doi-asserted-by":"publisher","award":["6-2021-0007"],"award-info":[{"award-number":["6-2021-0007"]}],"id":[{"id":"10.13039\/501100008005","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["thejcn.com"],"crossmark-restriction":false},"short-container-title":["J Clin Neurol"],"published-print":{"date-parts":[[2024]]},"DOI":"10.3988\/jcn.2023.0500","type":"journal-article","created":{"date-parts":[[2024,6,12]],"date-time":"2024-06-12T00:36:18Z","timestamp":1718152578000},"page":"519","update-policy":"https:\/\/doi.org\/10.3988\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Genetic Diagnosis in Neonatal Encephalopathy With Hypoxic Brain Damage Using Targeted Gene Panel Sequencing"],"prefix":"10.3988","volume":"20","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1148-7320","authenticated-orcid":false,"given":"Sangbo","family":"Lee","sequence":"first","affiliation":[{"name":"Division of Pediatric Neurology, Epilepsy Research Institute, Severance Hospital, Department of Pediatrics, Yonsei University College of Medicine, Seoul, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7773-1942","authenticated-orcid":false,"given":"Se Hee","family":"Kim","sequence":"additional","affiliation":[{"name":"Division of Pediatric Neurology, Epilepsy Research Institute, Severance Hospital, Department of Pediatrics, Yonsei University College of Medicine, Seoul, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8031-7336","authenticated-orcid":false,"given":"Heung Dong","family":"Kim","sequence":"additional","affiliation":[{"name":"Division of Pediatric Neurology, Epilepsy Research Institute, Severance Hospital, Department of Pediatrics, Yonsei University College of Medicine, Seoul, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9036-9343","authenticated-orcid":false,"given":"Joon Soo","family":"Lee","sequence":"additional","affiliation":[{"name":"Division of Pediatric Neurology, Epilepsy Research Institute, Severance Hospital, Department of Pediatrics, Yonsei University College of Medicine, Seoul, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3008-8432","authenticated-orcid":false,"given":"Ara","family":"Ko","sequence":"additional","affiliation":[{"name":"Division of Pediatric Neurology, Epilepsy Research Institute, Severance Hospital, Department of Pediatrics, Yonsei University College of Medicine, Seoul, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3659-8847","authenticated-orcid":false,"given":"Hoon-Chul","family":"Kang","sequence":"additional","affiliation":[{"name":"Division of Pediatric Neurology, Epilepsy Research Institute, Severance Hospital, Department of Pediatrics, Yonsei University College of Medicine, Seoul, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"18617","reference":[{"key":"10.3988\/jcn.2023.0500_ref1","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/0887-8994(92)90026-U","volume":"8","author":"Leviton","year":"1992","journal-title":"Pediatr Neurol"},{"key":"10.3988\/jcn.2023.0500_ref2","doi-asserted-by":"crossref","first-page":"1985","DOI":"10.1056\/NEJMra041996","volume":"351","author":"Ferriero","year":"2004","journal-title":"N Engl J Med"},{"key":"10.3988\/jcn.2023.0500_ref3","doi-asserted-by":"crossref","first-page":"567","DOI":"10.1111\/j.1469-8749.1974.tb04176.x","volume":"16","author":"Brown","year":"1974","journal-title":"Dev Med Child Neurol"},{"key":"10.3988\/jcn.2023.0500_ref4","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/0378-3782(85)90115-X","volume":"11","author":"Levene","year":"1985","journal-title":"Early Hum Dev"},{"key":"10.3988\/jcn.2023.0500_ref5","first-page":"25","volume-title":"Neurology of the newborn","author":"Volpe","year":"2001","edition":"4"},{"key":"10.3988\/jcn.2023.0500_ref6","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1016\/j.earlhumdev.2010.05.010","volume":"86","author":"Kurinczuk","year":"2010","journal-title":"Early Hum Dev"},{"key":"10.3988\/jcn.2023.0500_ref7","doi-asserted-by":"crossref","first-page":"1554","DOI":"10.1136\/bmj.317.7172.1554","volume":"317","author":"Badawi","year":"1998","journal-title":"BMJ"},{"key":"10.3988\/jcn.2023.0500_ref8","doi-asserted-by":"crossref","first-page":"1549","DOI":"10.1136\/bmj.317.7172.1549","volume":"317","author":"Badawi","year":"1998","journal-title":"BMJ"},{"key":"10.3988\/jcn.2023.0500_ref9","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1111\/j.1469-8749.2007.02007.x","volume":"50","author":"Blume","year":"2008","journal-title":"Dev Med Child Neurol"},{"key":"10.3988\/jcn.2023.0500_ref10","doi-asserted-by":"crossref","first-page":"878","DOI":"10.1542\/peds.2012-0714","volume":"130","author":"Nelson","year":"2012","journal-title":"Pediatrics"},{"key":"10.3988\/jcn.2023.0500_ref11","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1002\/ana.23647","volume":"72","author":"Volpe","year":"2012","journal-title":"Ann Neurol"},{"key":"10.3988\/jcn.2023.0500_ref12","doi-asserted-by":"crossref","first-page":"142","DOI":"10.3389\/fped.2019.00142","volume":"7","author":"Aslam","year":"2019","journal-title":"Front Pediatr"},{"key":"10.3988\/jcn.2023.0500_ref13","doi-asserted-by":"crossref","first-page":"101272","DOI":"10.1016\/j.siny.2021.101272","volume":"26","author":"Sandoval Karamian","year":"2021","journal-title":"Semin Fetal Neonatal Med"},{"key":"10.3988\/jcn.2023.0500_ref14","doi-asserted-by":"crossref","first-page":"486","DOI":"10.1038\/gim.2017.129","volume":"20","author":"Bruun","year":"2018","journal-title":"Genet Med"},{"key":"10.3988\/jcn.2023.0500_ref15","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1111\/cge.13818","volume":"98","author":"Yang","year":"2020","journal-title":"Clin Genet"},{"key":"10.3988\/jcn.2023.0500_ref16","first-page":"280","volume":"59","author":"Xiao","year":"2021","journal-title":"Zhonghua Er Ke Za Zhi"},{"key":"10.3988\/jcn.2023.0500_ref17","doi-asserted-by":"crossref","first-page":"113533","DOI":"10.1016\/j.jpeds.2023.113533","volume":"260","author":"Lenahan","year":"2023","journal-title":"J Pediatr"},{"key":"10.3988\/jcn.2023.0500_ref18","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1177\/08830738221147805","volume":"38","author":"Woodward","year":"2023","journal-title":"J Child Neurol"},{"key":"10.3988\/jcn.2023.0500_ref19","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1111\/j.1469-8749.1997.tb07414.x","volume":"39","author":"Palisano","year":"1997","journal-title":"Dev Med Child Neurol"},{"key":"10.3988\/jcn.2023.0500_ref20","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1001\/jamapediatrics.2014.3269","volume":"169","author":"Douglas-Escobar","year":"2015","journal-title":"JAMA Pediatr"},{"key":"10.3988\/jcn.2023.0500_ref21","doi-asserted-by":"crossref","first-page":"1491","DOI":"10.1007\/s00247-017-3893-y","volume":"47","author":"Trivedi","year":"2017","journal-title":"Pediatr Radiol"},{"key":"10.3988\/jcn.2023.0500_ref22","doi-asserted-by":"crossref","first-page":"101304","DOI":"10.1016\/j.siny.2021.101304","volume":"26","author":"Wisnowski","year":"2021","journal-title":"Semin Fetal Neonatal Med"},{"key":"10.3988\/jcn.2023.0500_ref23","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1038\/gim.2015.30","volume":"17","author":"Richards","year":"2015","journal-title":"Genet Med"},{"key":"10.3988\/jcn.2023.0500_ref24","doi-asserted-by":"crossref","first-page":"67","DOI":"10.5409\/wjcp.v5.i1.67","volume":"5","author":"Ahearne","year":"2016","journal-title":"World J Clin Pediatr"},{"key":"10.3988\/jcn.2023.0500_ref25","doi-asserted-by":"crossref","first-page":"2133","DOI":"10.2147\/NDT.S144225","volume":"13","author":"Alkholy","year":"2017","journal-title":"Neuropsychiatr Dis Treat"},{"key":"10.3988\/jcn.2023.0500_ref26","doi-asserted-by":"crossref","first-page":"169","DOI":"10.3345\/cep.2020.01459","volume":"64","author":"Shim","year":"2021","journal-title":"Clin Exp Pediatr"},{"key":"10.3988\/jcn.2023.0500_ref27","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1007\/s00408-013-9475-3","volume":"191","author":"Sun","year":"2013","journal-title":"Lung"},{"key":"10.3988\/jcn.2023.0500_ref28","doi-asserted-by":"crossref","first-page":"392","DOI":"10.1016\/j.arcped.2021.03.010","volume":"28","author":"Debillon","year":"2021","journal-title":"Arch Pediatr"},{"key":"10.3988\/jcn.2023.0500_ref29","doi-asserted-by":"crossref","first-page":"628066","DOI":"10.3389\/fneur.2021.628066","volume":"12","author":"Smyrni","year":"2021","journal-title":"Front Neurol"},{"key":"10.3988\/jcn.2023.0500_ref30","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1038\/nature12439","volume":"501","author":"Allen","year":"2013","journal-title":"Nature"},{"key":"10.3988\/jcn.2023.0500_ref31","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1016\/j.eplepsyres.2018.02.003","volume":"141","author":"Ko","year":"2018","journal-title":"Epilepsy Res"},{"key":"10.3988\/jcn.2023.0500_ref32","doi-asserted-by":"crossref","first-page":"106323","DOI":"10.1016\/j.eplepsyres.2020.106323","volume":"163","author":"Lee","year":"2020","journal-title":"Epilepsy Res"},{"key":"10.3988\/jcn.2023.0500_ref33","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1016\/j.braindev.2017.08.006","volume":"40","author":"Hayashida","year":"2018","journal-title":"Brain Dev"},{"key":"10.3988\/jcn.2023.0500_ref34","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1212\/WNL.0000000000000060","volume":"82","author":"Numis","year":"2014","journal-title":"Neurology"},{"key":"10.3988\/jcn.2023.0500_ref35","doi-asserted-by":"crossref","first-page":"958","DOI":"10.1212\/WNL.0000000000001926","volume":"85","author":"Howell","year":"2015","journal-title":"Neurology"},{"key":"10.3988\/jcn.2023.0500_ref36","doi-asserted-by":"crossref","first-page":"e1112","DOI":"10.1212\/WNL.0000000000006199","volume":"91","author":"Gardella","year":"2018","journal-title":"Neurology"},{"key":"10.3988\/jcn.2023.0500_ref37","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/j.ejpn.2021.05.010","volume":"33","author":"Le Roux","year":"2021","journal-title":"Eur J Paediatr Neurol"},{"key":"10.3988\/jcn.2023.0500_ref38","doi-asserted-by":"crossref","first-page":"e879","DOI":"10.1212\/WNL.0000000000207550","volume":"101","author":"Thalwitzer","year":"2023","journal-title":"Neurology"},{"key":"10.3988\/jcn.2023.0500_ref39","unstructured":"GeneReviews\u00ae [Internet]. Seattle. University of Washington, Seattle. 2022. cited 2023 Oct 23. Available from: https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK1479\/"},{"key":"10.3988\/jcn.2023.0500_ref40","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1055\/s-0042-1756447","volume":"22","author":"Singh","year":"2024","journal-title":"J Pediatr Neurol"},{"key":"10.3988\/jcn.2023.0500_ref41","first-page":"1111","volume":"10","author":"Lu","year":"2023","journal-title":"Children (Basel)"},{"key":"10.3988\/jcn.2023.0500_ref42","doi-asserted-by":"crossref","first-page":"1091","DOI":"10.1002\/ajmg.a.38684","volume":"176","author":"Alby","year":"2018","journal-title":"Am J Med Genet A"},{"key":"10.3988\/jcn.2023.0500_ref43","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1002\/ajmg.a.61024","volume":"179","author":"Cleaver","year":"2019","journal-title":"Am J Med Genet A"},{"key":"10.3988\/jcn.2023.0500_ref44","unstructured":"GeneReviews\u00ae [Internet]. Seattle. University of Washington, Seattle. 2017. cited 2023 Oct 23. Available from: https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK426063\/"},{"key":"10.3988\/jcn.2023.0500_ref45","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1097\/MCD.0000000000000360","volume":"30","author":"Mishra","year":"2021","journal-title":"Clin Dysmorphol"},{"key":"10.3988\/jcn.2023.0500_ref46","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1016\/j.stem.2015.07.002","volume":"17","author":"Llorens-Bobadilla","year":"2015","journal-title":"Cell Stem Cell"},{"key":"10.3988\/jcn.2023.0500_ref47","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1002\/ibra.12025","volume":"8","author":"Zhou","year":"2022","journal-title":"Ibrain"}],"container-title":["Journal of Clinical Neurology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/thejcn.com\/pdf\/10.3988\/jcn.2023.0500","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/thejcn.com\/DOIx.php?id=10.3988\/jcn.2023.0500","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/thejcn.com\/DOIx.php?id=10.3988\/jcn.2023.0500","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,8,30]],"date-time":"2024-08-30T00:48:56Z","timestamp":1724978936000},"score":1,"resource":{"primary":{"URL":"https:\/\/thejcn.com\/DOIx.php?id=10.3988\/jcn.2023.0500"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024]]},"references-count":47,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2024]]}},"URL":"https:\/\/doi.org\/10.3988\/jcn.2023.0500","relation":{},"ISSN":["1738-6586","2005-5013"],"issn-type":[{"value":"1738-6586","type":"print"},{"value":"2005-5013","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024]]},"assertion":[{"value":"2023-12-11","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-02-28","name":"revised","label":"Revised","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-03-26","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-06-05","name":"published_online","label":"Published online","group":{"name":"publication_history","label":"Publication History"}},{"value":"Copyright \u00a9 2024 Korean Neurological Association","name":"copyright","label":"Copyright","group":{"name":"Copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (https:\/\/creativecommons.org\/licenses\/by-nc\/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.","name":"license","label":"License","explanation":{"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0"},"group":{"name":"Copyright_and_licensing","label":"Copyright and Licensing"}}]}}