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The longer-term financial consequences of such interventions, however, are more uncertain. This study offers a System Dynamics simulation framework that identifies and models the critical relationships associated with health outcomes and longer-term financial consequences. This framework is demonstrated through a comparison between groups with a similar generic chronic condition, but one group is subjected to a management intervention and the other group is not. The framework provides constructive insights into how the initial intervention cost estimates, the resulting savings, and the health status may change depending on uncertainties, feedback effects, and cost structures.<\/p>","DOI":"10.4018\/ijisss.2014100103","type":"journal-article","created":{"date-parts":[[2014,12,22]],"date-time":"2014-12-22T12:59:38Z","timestamp":1419253178000},"page":"40-59","source":"Crossref","is-referenced-by-count":1,"title":["A Simulation Framework for Evaluating the Effectiveness of Chronic Disease Management Interventions"],"prefix":"10.4018","volume":"6","author":[{"given":"Rafael","family":"Diaz","sequence":"first","affiliation":[{"name":"Virginia Modeling, Analysis, and Simulation Center, Old Dominion University, Suffolk, VA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joshua G.","family":"Behr","sequence":"additional","affiliation":[{"name":"Virginia Modeling, Analysis, and Simulation Center, Old Dominion University, Suffolk, VA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2432","reference":[{"key":"ijisss.2014100103-0","doi-asserted-by":"publisher","DOI":"10.1002\/hec.1095"},{"key":"ijisss.2014100103-1","doi-asserted-by":"publisher","DOI":"10.1016\/j.phr.2004.04.005"},{"key":"ijisss.2014100103-2","doi-asserted-by":"publisher","DOI":"10.1177\/1077558706293637"},{"key":"ijisss.2014100103-3","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.160.12.2080"},{"key":"ijisss.2014100103-4","doi-asserted-by":"publisher","DOI":"10.1071\/PY03022"},{"key":"ijisss.2014100103-5","doi-asserted-by":"publisher","DOI":"10.1001\/jama.288.19.2469"},{"key":"ijisss.2014100103-6","unstructured":"Chen, H.-Y., & Rice, D. 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