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The structure of the model has been built from a physiological base, considering some of the mechanisms associated to the cardiovascular system. Thus, the aim of the model is the prediction, heartbeat by heartbeat, of some hemodynamic variables from the cardiovascular system, in different pathophysiological cardiac situations. A modular approach to development of the model has been considered in order to include new knowledge that could force the model's hemodynamic. The model has been validated comparing the results obtained with hemodynamic values published by other authors. The results show the usefulness and applicability of the model developed. Thus, different simulations of some cardiac pathologies and physical exercise situations are presented, together with the dynamic behaviors of the different variables considered in the model.<\/p>","DOI":"10.4018\/ijsda.2014040106","type":"journal-article","created":{"date-parts":[[2014,9,15]],"date-time":"2014-09-15T12:28:58Z","timestamp":1410784138000},"page":"81-98","source":"Crossref","is-referenced-by-count":1,"title":["Computational Hemodynamic Modeling of the Cardiovascular System"],"prefix":"10.4018","volume":"3","author":[{"given":"Alejandro","family":"Talaminos","sequence":"first","affiliation":[{"name":"University of Seville, Seville, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laura M.","family":"Roa","sequence":"additional","affiliation":[{"name":"CIBER-BBN, University of Seville, Seville, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antonio","family":"\u00c1lvarez","sequence":"additional","affiliation":[{"name":"University of Seville, Seville, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Javier","family":"Reina","sequence":"additional","affiliation":[{"name":"CIBER-BBN, University of Seville, Seville, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2432","reference":[{"key":"ijsda.2014040106-0","doi-asserted-by":"publisher","DOI":"10.1186\/1532-429X-15-89"},{"key":"ijsda.2014040106-1","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1145\/2037509.2037525","article-title":"Toward real-time simulation of cardiac dynamics.","author":"E.Bartocci","year":"2011","journal-title":"Proceedings of the 9th International Conference on Computational Methods in Systems Biology"},{"key":"ijsda.2014040106-2","first-page":"773","article-title":"Fuzzy-logic based automatic control of hemodynamics.","volume":"2003","author":"R.Bauernschmitt","year":"2003","journal-title":"Computers in Cardiology"},{"key":"ijsda.2014040106-3","doi-asserted-by":"publisher","DOI":"10.1093\/ejechocard\/jen303"},{"key":"ijsda.2014040106-4","doi-asserted-by":"publisher","DOI":"10.1109\/ISABEL.2008.4712624"},{"key":"ijsda.2014040106-5","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.104.532498"},{"issue":"4","key":"ijsda.2014040106-6","doi-asserted-by":"crossref","DOI":"10.70252\/CTWV5704","article-title":"Age-related differences in systolic blood pressure recovery after a maximal-effort exercise test in non-athletic adults.","volume":"1","author":"U.Dimkpa","year":"2008","journal-title":"International Journal of Exercise Science"},{"key":"ijsda.2014040106-7","doi-asserted-by":"publisher","DOI":"10.1016\/j.irbm.2013.01.001"},{"key":"ijsda.2014040106-8","unstructured":"El-Brawany, M. 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