{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,4,14]],"date-time":"2025-04-14T18:42:11Z","timestamp":1744656131668},"reference-count":23,"publisher":"IGI Global","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2011,10,1]]},"abstract":"<p>A new portable measuring device for monitoring intraocular pressure with a non invasive system using a prototype of contact lens has been developed. The contact lens is based on a new organic flexible highly piezo-resisitive film sensor that is glued to the central hole of a lens. The measuring system is wire connected to the contact lens and incorporates user interface methods and a Bluetooth link for bi-directional wireless data transfer. The key design aspects of such architecture are discussed in this paper. The system is designed with an architecture that can be integrated in the future in order to be placed in the contact lens. The discrete system is used to validate the electronic measurement operation and the contact lens sensor (CLS). The measurement instrument can calibrate the differences of the nominal value of the sensor and measure resistances variations that are related to pressure variations. The measuring system and the contact lens sensor were tested with an eye phantom and with enucleated pig eyes by applying pressure changes between 7 to 32 mmHg recording the electrical changes with the portable device.<\/p>","DOI":"10.4018\/jehmc.2011100101","type":"journal-article","created":{"date-parts":[[2011,10,19]],"date-time":"2011-10-19T16:18:04Z","timestamp":1319041084000},"page":"1-19","source":"Crossref","is-referenced-by-count":1,"title":["Discrete Portable Measuring Device for Monitoring Noninvasive Intraocular Pressure with a Nano-Structured Sensing Contact Lens Prototype"],"prefix":"10.4018","volume":"2","author":[{"given":"Ana","family":"Moya","sequence":"first","affiliation":[{"name":"CIBER-BBN and IMB-CNM (CSIC), Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anton","family":"Guimer\u00e0","sequence":"additional","affiliation":[{"name":"CIBER-BBN and IMB-CNM (CSIC), Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Irene","family":"S\u00e1nchez","sequence":"additional","affiliation":[{"name":"CIBER-BBN and IOBA, University of Valladolidad, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vladimir","family":"Laukin","sequence":"additional","affiliation":[{"name":"ICREA and ICMAB (CSIC), Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ra\u00fal","family":"Mart\u00edn","sequence":"additional","affiliation":[{"name":"CIBER-BBN, Department of Physics TAO and IOBA, University of Valladolid, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fernando","family":"Ussa","sequence":"additional","affiliation":[{"name":"CIBER-BBN and IOBA, University of Valladolid, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elena","family":"Laukhina","sequence":"additional","affiliation":[{"name":"CIBER-BBN and ICMAB (CSIC), Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Concepci\u00f3","family":"Rovira","sequence":"additional","affiliation":[{"name":"CIBER-BBN and ICMAB (CSIC), Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jaume","family":"Veciana","sequence":"additional","affiliation":[{"name":"CIBER-BBN and ICMAB (CSIC), Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jos\u00e9 Carlos","family":"Pastor","sequence":"additional","affiliation":[{"name":"CIBER-BBN, University Hospital and IOBA, University of Valladolid, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rosa","family":"Villa","sequence":"additional","affiliation":[{"name":"CIBER-BBN and IMB-CNM (CSIC), Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jordi","family":"Aguil\u00f3","sequence":"additional","affiliation":[{"name":"CIBER-BBN and IMB-CNM (CSIC), Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2432","reference":[{"key":"jehmc.2011100101-0","doi-asserted-by":"publisher","DOI":"10.1109\/TNN.2003.816357"},{"key":"jehmc.2011100101-1","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1097\/00061198-200004000-00002","article-title":"Large diurnal fluctuations in intraocular pressure are an independent risk factor in patients with glaucoma.","volume":"9","author":"S.Asrani","year":"2000","journal-title":"Journal of Glaucoma"},{"key":"jehmc.2011100101-2","doi-asserted-by":"publisher","DOI":"10.1109\/JSSC.2007.905295"},{"key":"jehmc.2011100101-3","doi-asserted-by":"publisher","DOI":"10.1109\/TCSI.2009.2015210"},{"key":"jehmc.2011100101-4","doi-asserted-by":"publisher","DOI":"10.1159\/000265179"},{"issue":"4","key":"jehmc.2011100101-5","first-page":"299","article-title":"Intraocular pressure measurement with instrumented contact lenses.","volume":"13","author":"M. 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Argentina Patent No. ES2330405-A1; WO2009147277-A1: Truncated contact lens for use in telemetry system, has truncation plane provided parallel to base of lens, and centrally placed polymer nanocomposite material joined to perimeter of truncated zone. Buenos Aries, Argentina: The Argentina Trademark System."},{"key":"jehmc.2011100101-11","unstructured":"Laukhina, E., Mas-Torrent, M., Rovira, C., Veciana, J., & Laukhin, V. (2006). Argentina Patent No. P200602887 (WO2008059095): Organic sensor device for e.g., molecular electronics, has layer of organic material having conductive salt or complex including molecule and dopant, and base substrate provided in close contact with layer of organic material. Buenos Aries, Argentina: The Argentina Trademark System."},{"key":"jehmc.2011100101-12","doi-asserted-by":"crossref","first-page":"977","DOI":"10.1002\/adma.200902639","article-title":"Ultrasensitive piezoresistive all-organic flexible thin films.","volume":"22","author":"E.Laukhina","year":"2010","journal-title":"Advanced Materials (Deerfield Beach, Fla.)"},{"key":"jehmc.2011100101-13","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.04-0015"},{"key":"jehmc.2011100101-14","doi-asserted-by":"publisher","DOI":"10.1111\/j.1755-3768.2008.01404.x"},{"key":"jehmc.2011100101-15","doi-asserted-by":"publisher","DOI":"10.1109\/JSSC.2007.914337"},{"key":"jehmc.2011100101-16","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.42.6.321"},{"key":"jehmc.2011100101-17","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.2005.074948"},{"key":"jehmc.2011100101-18","first-page":"844","article-title":"Global data on visual impairment in the year 2002.","volume":"82","author":"S.Resnikoff","year":"2004","journal-title":"Bulletin of the World Health Organization"},{"key":"jehmc.2011100101-19","doi-asserted-by":"publisher","DOI":"10.1097\/00061198-199612000-00009"},{"key":"jehmc.2011100101-20","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.2005.072751"},{"key":"jehmc.2011100101-21","doi-asserted-by":"publisher","DOI":"10.1111\/j.1755-3768.1992.tb04135.x"},{"key":"jehmc.2011100101-22","doi-asserted-by":"publisher","DOI":"10.1007\/BF00136208"}],"container-title":["International Journal of E-Health and Medical Communications"],"original-title":[],"language":"ng","link":[{"URL":"https:\/\/www.igi-global.com\/viewtitle.aspx?TitleId=60203","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,6,1]],"date-time":"2022-06-01T23:15:43Z","timestamp":1654125343000},"score":1,"resource":{"primary":{"URL":"https:\/\/services.igi-global.com\/resolvedoi\/resolve.aspx?doi=10.4018\/jehmc.2011100101"}},"subtitle":[""],"short-title":[],"issued":{"date-parts":[[2011,10,1]]},"references-count":23,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2011,10]]}},"URL":"https:\/\/doi.org\/10.4018\/jehmc.2011100101","relation":{},"ISSN":["1947-315X","1947-3168"],"issn-type":[{"value":"1947-315X","type":"print"},{"value":"1947-3168","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,10,1]]}}}