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However, such an approach may not be a robust solution to this problem because it ignores the fact that some genes are more informative than others in species inference. This paper presents a self-organizing map (SOM) based phylogeny inference method to overcome its weakness. The author\u2019s proposed algorithm not only demonstrates its superiority to the original gene concatenation method by using same datasets, but also shows its advantages in generalization. This paper illustrates that data missing may not play a negative role in phylogeny inferring. This study presents a method to cluster multispecies genes, estimate multispecies gene entropy and visualize the species patterns through the self-organizing map mining.<\/p>","DOI":"10.4018\/jkdb.2010040103","type":"journal-article","created":{"date-parts":[[2010,7,1]],"date-time":"2010-07-01T00:57:02Z","timestamp":1277945822000},"page":"29-49","source":"Crossref","is-referenced-by-count":0,"title":["Infer Species Phylogenies Using Self-Organizing Maps"],"prefix":"10.4018","volume":"1","author":[{"given":"Xiaoxu","family":"Han","sequence":"first","affiliation":[{"name":"Eastern Michigan University, USA"}]}],"member":"2432","reference":[{"key":"jkdb.2010040103-0","doi-asserted-by":"publisher","DOI":"10.1145\/1183907.1183909"},{"key":"jkdb.2010040103-1","doi-asserted-by":"publisher","DOI":"10.1038\/nrg1603"},{"key":"jkdb.2010040103-2","doi-asserted-by":"crossref","DOI":"10.1201\/9780203486078","author":"S.Draghici","year":"2003","journal-title":"Data Analysis Tools for DNA Microarrays"},{"journal-title":"Probabilistic models of proteins and nucleic acids","year":"1998","author":"R.Durbin","key":"jkdb.2010040103-3"},{"journal-title":"Inferring Phylogenies","year":"2004","author":"J.Felsentein","key":"jkdb.2010040103-4"},{"key":"jkdb.2010040103-5","doi-asserted-by":"publisher","DOI":"10.1016\/S0168-9525(00)02005-9"},{"key":"jkdb.2010040103-6","doi-asserted-by":"publisher","DOI":"10.1186\/gb-2007-8-7-r141"},{"key":"jkdb.2010040103-7","doi-asserted-by":"crossref","DOI":"10.1007\/978-0-387-84858-7","author":"T.Hastie","year":"2009","journal-title":"The elements of statistical learning: data mining, inference and prediction"},{"journal-title":"Neural Networks: A Comprehensive Foundation","year":"1999","author":"S.Haykin","key":"jkdb.2010040103-8"},{"key":"jkdb.2010040103-9","first-page":"5061","article-title":"Entropies of biosequences: the role of repeats.","volume":"50","author":"H.Herzel","year":"1994","journal-title":"Physical Review"},{"key":"jkdb.2010040103-10","first-page":"843","article-title":"The robustness of two phylogenetic methods: Four-taxon simulations reveal a slight superiority of maximum likelihood over neighbor joining.","volume":"12","author":"J.Huelsenbeck","year":"1995","journal-title":"Molecular Biology and Evolution"},{"key":"jkdb.2010040103-11","doi-asserted-by":"publisher","DOI":"10.1080\/10635150290102366"},{"key":"jkdb.2010040103-12","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/17.8.754"},{"key":"jkdb.2010040103-13","doi-asserted-by":"crossref","DOI":"10.1007\/978-3-642-56927-2","author":"T.Kohonen","year":"2001","journal-title":"Self-Organizing Maps"},{"key":"jkdb.2010040103-14","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.genet.39.073003.114725"},{"key":"jkdb.2010040103-15","doi-asserted-by":"publisher","DOI":"10.1111\/j.1558-5646.2008.00414.x"},{"key":"jkdb.2010040103-16","doi-asserted-by":"publisher","DOI":"10.1137\/S0097539798343362"},{"key":"jkdb.2010040103-17","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1093\/oso\/9780198566106.003.0012","article-title":"Reconstructing phylogenies from gene-content and gene-order data","author":"B.Moret","year":"2005","journal-title":"Mathematics of Evolution and Phylogeny"},{"key":"jkdb.2010040103-18","doi-asserted-by":"crossref","DOI":"10.1093\/oso\/9780195135848.001.0001","author":"M.Nei","year":"2000","journal-title":"Molecular Evolution and Phylogenetics"},{"key":"jkdb.2010040103-19","doi-asserted-by":"publisher","DOI":"10.1016\/S0893-6080(02)00070-9"},{"key":"jkdb.2010040103-20","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btn556"},{"key":"jkdb.2010040103-21","doi-asserted-by":"publisher","DOI":"10.1101\/gr.7105007"},{"journal-title":"Self-organizing feature maps: Kohnnen maps. 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