{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,29]],"date-time":"2025-10-29T03:26:42Z","timestamp":1761708402188},"reference-count":16,"publisher":"AACN Publishing","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2009,9,1]]},"abstract":"<jats:p>Background Perioperative outcome data related to metabolic syndrome in coronary artery bypass graft (CABG) patients are lacking.<\/jats:p>\n               <jats:p>Objective To determine the incidence of metabolic syndrome in CABG patients and whether its presence or the patient\u2019s sex affects postoperative lengths of stay in the intensive care unit and hospital.<\/jats:p>\n               <jats:p>Methods A retrospective observational study in CABG patients. Risk factors from the Society of Thoracic Surgeons\u2019 Adult Cardiac Surgery Database were used to categorize patients as having metabolic syndrome. Perioperative outcomes were compared between patients with and without metabolic syndrome and between sexes. Outcomes were based on the operational definitions of the Society of Thoracic Surgeons. Results Among 657 patients, 333 had metabolic syndrome; 63.8% (n = 215) of women and 36.9% (n = 118) of men (P \u2264 .001). Mean postoperative stays were significantly longer in patients who had metabolic syndrome. Women had longer postoperative stays than did men. Mean postoperative stay for women was 2.7 (SD, 3.4) days in the intensive care unit and 8.2 (SD, 7.1) days in the hospital, compared with 2.0 (SD, 3.8) days in the intensive care unit (P = .01) and 6.6 (SD, 6.8) days in the hospital for men (P = .003). Women with metabolic syndrome also had higher rates of in-hospital death (P = .03).<\/jats:p>\n               <jats:p>Conclusion Both female patients and patients with metabolic syndrome undergoing CABG surgery are at higher risk for longer postoperative stays. Women with metabolic syndrome are the CABG patients at highest risk for in-hospital death.<\/jats:p>","DOI":"10.4037\/ajcc2009718","type":"journal-article","created":{"date-parts":[[2009,9,1]],"date-time":"2009-09-01T16:03:58Z","timestamp":1251821038000},"page":"468-473","source":"Crossref","is-referenced-by-count":18,"title":["Perioperative Outcomes of Coronary Artery Bypass Grafting: Effects of Metabolic Syndrome and Patient\u2019s Sex"],"prefix":"10.4037","volume":"18","author":[{"given":"Marcia L.","family":"Brackbill","sequence":"first","affiliation":[{"name":"Marcia L. Brackbill is a cardiovascular clinical pharmacy specialist and Christine S. Sytsma is the director of outcomes at Winchester Medical Center\u2019s Heart and Vascular Center in Winchester, Virginia. Brackbill is also an associate professor in the Bernard J. Dunn School of Pharmacy at Shenandoah University in Winchester, Virginia. Kristina Sykes was a student at Shenandoah University when this research was completed."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christine S.","family":"Sytsma","sequence":"first","affiliation":[{"name":"Marcia L. Brackbill is a cardiovascular clinical pharmacy specialist and Christine S. Sytsma is the director of outcomes at Winchester Medical Center\u2019s Heart and Vascular Center in Winchester, Virginia. Brackbill is also an associate professor in the Bernard J. Dunn School of Pharmacy at Shenandoah University in Winchester, Virginia. Kristina Sykes was a student at Shenandoah University when this research was completed."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kristina","family":"Sykes","sequence":"first","affiliation":[{"name":"Marcia L. Brackbill is a cardiovascular clinical pharmacy specialist and Christine S. Sytsma is the director of outcomes at Winchester Medical Center\u2019s Heart and Vascular Center in Winchester, Virginia. Brackbill is also an associate professor in the Bernard J. Dunn School of Pharmacy at Shenandoah University in Winchester, Virginia. Kristina Sykes was a student at Shenandoah University when this research was completed."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2471","reference":[{"key":"2020032809361951400_R1","doi-asserted-by":"crossref","unstructured":"National Cholesterol Education Program. 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JAMA. 2002;288(21):2709\u20132716.","DOI":"10.1001\/jama.288.21.2709"},{"key":"2020032809361951400_R4","doi-asserted-by":"crossref","unstructured":"Hunt\n            KJ\n          , Resendez RG, Williams K, Haffner SM, Stern MP; San Antonio Heart Study. National Cholesterol Education Program versus World Health Organization metabolic syndrome in relation to all-cause and cardiovascular mortality in the San Antonio Heart Study. Circulation. 2004;110(10): 1251\u20131257.","DOI":"10.1161\/01.CIR.0000140762.04598.F9"},{"key":"2020032809361951400_R5","doi-asserted-by":"crossref","unstructured":"Sundstro\u0308m\n            J\n          , Rise\u0301rus U, Byberg L, Zethelius B, Lithell H, Lind L. Clinical value of the metabolic syndrome for long term prediction of total cardiovascular mortality: prospective, population based cohort study. BMJ. 2006;332(7546):878\u2013882.","DOI":"10.1136\/bmj.38766.624097.1F"},{"key":"2020032809361951400_R6","doi-asserted-by":"crossref","unstructured":"Carson\n            JL\n          , Scholz PM, Chen AY, Peterson ED, Gold J, Schneider SH. Diabetes mellitus increases short term mortality and morbidity in patients undergoing coronary artery bypass graft surgery. J Am Coll Cardiol. 2002;40(30):424\u2013427.","DOI":"10.1016\/S0735-1097(02)01969-1"},{"key":"2020032809361951400_R7","doi-asserted-by":"crossref","unstructured":"Sprecher\n            DL\n          , Pearce GL, Park EM, Pashkow FJ, Hoogwerf BJ. Preoperative triglycerides predict post-coronary artery bypass graft survival in diabetes: a sex analysis. Diabetes Care. 2000;23(11):1648\u20131653.","DOI":"10.2337\/diacare.23.11.1648"},{"key":"2020032809361951400_R8","doi-asserted-by":"crossref","unstructured":"Yilmaz\n            MB\n          , Guray U, Guray Y, et al. Metabolic syndrome negatively impacts early patency of saphenous vein grafts. Coron Artery Dis. 2006;17(1):41\u201344.","DOI":"10.1097\/00019501-200602000-00007"},{"key":"2020032809361951400_R9","doi-asserted-by":"crossref","unstructured":"Echahidi\n            N\n          , Mohty D, Pibarot P, et al. Obesity and metabolic syndrome are independent risk factors for atrial fibrillation after coronary artery bypass graft surgery. Circulation. 2007;116(11 suppl I):213\u2013219.","DOI":"10.1161\/CIRCULATIONAHA.106.681304"},{"key":"2020032809361951400_R10","doi-asserted-by":"crossref","unstructured":"Sprecher\n            DL\n          , Pearce GL. How deadly is the \u201cdeadly quartet\u201d?: A post-CABG evaluation. J Am Coll Cardiol. 2000;36(4): 1159\u20131165.","DOI":"10.1016\/S0735-1097(00)00867-6"},{"key":"2020032809361951400_R11","doi-asserted-by":"crossref","unstructured":"McTigue\n            K\n          , Larson JC, Valoski A, et al. Mortality and cardiac and vascular outcomes in extremely obese women. JAMA. 2006;296:79\u201386.","DOI":"10.1001\/jama.296.1.79"},{"key":"2020032809361951400_R12","doi-asserted-by":"crossref","unstructured":"Rong\n            HU\n          , Chang-sheng MA, Shao-ping NIE, et al. Effect of metabolic syndrome on prognosis and clinical characteristics of revascularization in patients with coronary artery disease. Chin Med J. 2006;119(22):1871\u20131876.","DOI":"10.1097\/00029330-200611020-00005"},{"key":"2020032809361951400_R13","doi-asserted-by":"crossref","unstructured":"Puskas\n            JD\n          , Edwards FH, Pappas PA, et al. Off-pump techniques benefit men and women and narrow the disparity in mortality after coronary bypass grafting. 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Endocr J. 2002;49(5):531\u2013537.","DOI":"10.1507\/endocrj.49.531"}],"container-title":["American Journal of Critical Care"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/aacnjournals.org\/ajcconline\/article-pdf\/18\/5\/468\/93548\/468.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"http:\/\/aacnjournals.org\/ajcconline\/article-pdf\/18\/5\/468\/93548\/468.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,3,28]],"date-time":"2020-03-28T13:36:51Z","timestamp":1585402611000},"score":1,"resource":{"primary":{"URL":"https:\/\/aacnjournals.org\/ajcconline\/article\/18\/5\/468\/5760\/Perioperative-Outcomes-of-Coronary-Artery-Bypass"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,9,1]]},"references-count":16,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2009,9,1]]}},"URL":"https:\/\/doi.org\/10.4037\/ajcc2009718","relation":{},"ISSN":["1062-3264","1937-710X"],"issn-type":[{"value":"1062-3264","type":"print"},{"value":"1937-710X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,9,1]]}}}