{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,20]],"date-time":"2026-04-20T16:35:40Z","timestamp":1776702940374,"version":"3.51.2"},"reference-count":49,"publisher":"AACN Publishing","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2013,11,1]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Inadequate nutrition support is common among critically ill patients, and identification of risk factors for such inadequacy might help in improving nutrition support.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objective<\/jats:title><jats:p>To determine how often daily calorie goals are met and the factors responsible for inadequate nutrition support.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A single-center prospective cohort study. Each patient\u2019s demographic and clinical characteristics, the need for ventilatory support, the use and dosage of medications, the number of nursing staff per bed, the time elapsed from admission to the intensive care unit until the effective start of enteral feeding, and the causes for nonadministration were recorded. Achievement of daily calorie goals was determined and correlated with risk factors.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 262 daily evaluations were done in 40 patients. Daily calorie goal was achieved in only 46.2% of the evaluations (n = 121), with a mean of 74.8% of the prescribed volume of enteral nutrition infused daily. Risk factors for inadequate nutrition support were the use of midazolam (odds ratio, 1.58; 95% CI, 1.18\u20132.11) and fewer nursing professionals per bed (odds ratio, 2.56; 95% CI, 1.43\u20134.57).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Achievement of daily calorie goals was inadequate, and the main factors associated with this failure were the use and dosage of midazolam and the number of nurses available.<\/jats:p><\/jats:sec>","DOI":"10.4037\/ajcc2013610","type":"journal-article","created":{"date-parts":[[2013,11,1]],"date-time":"2013-11-01T09:00:23Z","timestamp":1383296423000},"page":"e71-e78","source":"Crossref","is-referenced-by-count":13,"title":["Nurse to Bed Ratio and Nutrition Support in Critically Ill Patients"],"prefix":"10.4037","volume":"22","author":[{"given":"Carolina Keiko Yamamoto","family":"Honda","sequence":"first","affiliation":[{"name":"Most of the authors are employed in the Anesthesiology, Pain, and Intensive Care Department, Federal University of Sao Paulo, Sao Paulo, SP, Brazil: Carolina Keiko Yamamoto Honda, Fl\u00e1vio Geraldo Rezende Freitas, and Bruno Franco Mazza are physicians, Isac Castro is a statistician, and Ana Paula Metran Nascentev, Antonio Toneti Bafi, Luciano Cesar Pontes Azevedo, and Fl\u00e1via Ribeiro Machado are physicians. Patricia Stanich is a nutritionist at Hospital Sao Paulo, Sao Paulo, SP, Brazil."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fl\u00e1vio Geraldo Rezende","family":"Freitas","sequence":"first","affiliation":[{"name":"Most of the authors are employed in the Anesthesiology, Pain, and Intensive Care Department, Federal University of Sao Paulo, Sao Paulo, SP, Brazil: Carolina Keiko Yamamoto Honda, Fl\u00e1vio Geraldo Rezende Freitas, and Bruno Franco Mazza are physicians, Isac Castro is a statistician, and Ana Paula Metran Nascentev, Antonio Toneti Bafi, Luciano Cesar Pontes Azevedo, and Fl\u00e1via Ribeiro Machado are physicians. Patricia Stanich is a nutritionist at Hospital Sao Paulo, Sao Paulo, SP, Brazil."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patricia","family":"Stanich","sequence":"first","affiliation":[{"name":"Most of the authors are employed in the Anesthesiology, Pain, and Intensive Care Department, Federal University of Sao Paulo, Sao Paulo, SP, Brazil: Carolina Keiko Yamamoto Honda, Fl\u00e1vio Geraldo Rezende Freitas, and Bruno Franco Mazza are physicians, Isac Castro is a statistician, and Ana Paula Metran Nascentev, Antonio Toneti Bafi, Luciano Cesar Pontes Azevedo, and Fl\u00e1via Ribeiro Machado are physicians. Patricia Stanich is a nutritionist at Hospital Sao Paulo, Sao Paulo, SP, Brazil."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bruno Franco","family":"Mazza","sequence":"first","affiliation":[{"name":"Most of the authors are employed in the Anesthesiology, Pain, and Intensive Care Department, Federal University of Sao Paulo, Sao Paulo, SP, Brazil: Carolina Keiko Yamamoto Honda, Fl\u00e1vio Geraldo Rezende Freitas, and Bruno Franco Mazza are physicians, Isac Castro is a statistician, and Ana Paula Metran Nascentev, Antonio Toneti Bafi, Luciano Cesar Pontes Azevedo, and Fl\u00e1via Ribeiro Machado are physicians. Patricia Stanich is a nutritionist at Hospital Sao Paulo, Sao Paulo, SP, Brazil."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Isac","family":"Castro","sequence":"first","affiliation":[{"name":"Most of the authors are employed in the Anesthesiology, Pain, and Intensive Care Department, Federal University of Sao Paulo, Sao Paulo, SP, Brazil: Carolina Keiko Yamamoto Honda, Fl\u00e1vio Geraldo Rezende Freitas, and Bruno Franco Mazza are physicians, Isac Castro is a statistician, and Ana Paula Metran Nascentev, Antonio Toneti Bafi, Luciano Cesar Pontes Azevedo, and Fl\u00e1via Ribeiro Machado are physicians. Patricia Stanich is a nutritionist at Hospital Sao Paulo, Sao Paulo, SP, Brazil."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ana Paula Metran","family":"Nascente","sequence":"first","affiliation":[{"name":"Most of the authors are employed in the Anesthesiology, Pain, and Intensive Care Department, Federal University of Sao Paulo, Sao Paulo, SP, Brazil: Carolina Keiko Yamamoto Honda, Fl\u00e1vio Geraldo Rezende Freitas, and Bruno Franco Mazza are physicians, Isac Castro is a statistician, and Ana Paula Metran Nascentev, Antonio Toneti Bafi, Luciano Cesar Pontes Azevedo, and Fl\u00e1via Ribeiro Machado are physicians. Patricia Stanich is a nutritionist at Hospital Sao Paulo, Sao Paulo, SP, Brazil."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antonio Toneti","family":"Bafi","sequence":"first","affiliation":[{"name":"Most of the authors are employed in the Anesthesiology, Pain, and Intensive Care Department, Federal University of Sao Paulo, Sao Paulo, SP, Brazil: Carolina Keiko Yamamoto Honda, Fl\u00e1vio Geraldo Rezende Freitas, and Bruno Franco Mazza are physicians, Isac Castro is a statistician, and Ana Paula Metran Nascentev, Antonio Toneti Bafi, Luciano Cesar Pontes Azevedo, and Fl\u00e1via Ribeiro Machado are physicians. Patricia Stanich is a nutritionist at Hospital Sao Paulo, Sao Paulo, SP, Brazil."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luciano Cesar Pontes","family":"Azevedo","sequence":"first","affiliation":[{"name":"Most of the authors are employed in the Anesthesiology, Pain, and Intensive Care Department, Federal University of Sao Paulo, Sao Paulo, SP, Brazil: Carolina Keiko Yamamoto Honda, Fl\u00e1vio Geraldo Rezende Freitas, and Bruno Franco Mazza are physicians, Isac Castro is a statistician, and Ana Paula Metran Nascentev, Antonio Toneti Bafi, Luciano Cesar Pontes Azevedo, and Fl\u00e1via Ribeiro Machado are physicians. Patricia Stanich is a nutritionist at Hospital Sao Paulo, Sao Paulo, SP, Brazil."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fl\u00e1via Ribeiro","family":"Machado","sequence":"first","affiliation":[{"name":"Most of the authors are employed in the Anesthesiology, Pain, and Intensive Care Department, Federal University of Sao Paulo, Sao Paulo, SP, Brazil: Carolina Keiko Yamamoto Honda, Fl\u00e1vio Geraldo Rezende Freitas, and Bruno Franco Mazza are physicians, Isac Castro is a statistician, and Ana Paula Metran Nascentev, Antonio Toneti Bafi, Luciano Cesar Pontes Azevedo, and Fl\u00e1via Ribeiro Machado are physicians. Patricia Stanich is a nutritionist at Hospital Sao Paulo, Sao Paulo, SP, Brazil."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2471","reference":[{"issue":"3","key":"2020032806034205400_b1-0220e71","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1007\/s001340050326","article-title":"A study of problems associated with the delivery of enteral feed in critically ill patients in five ICUs in the UK","volume":"23","author":"Adam","year":"1997","journal-title":"Intensive Care Med"},{"issue":"3","key":"2020032806034205400_b2-0220e71","doi-asserted-by":"crossref","first-page":"R218","DOI":"10.1186\/cc3504","article-title":"Daily enteral feeding practice on the ICU: attainment of goals and interfering factors","volume":"9","author":"Binnekade","year":"2005","journal-title":"Crit Care"},{"issue":"6","key":"2020032806034205400_b3-0220e71","doi-asserted-by":"crossref","first-page":"1055","DOI":"10.1097\/00003246-199506000-00010","article-title":"Enteral nutrition in the critically ill patient: a prospective survey","volume":"23","author":"Heyland","year":"1995","journal-title":"Crit Care Med"},{"issue":"7","key":"2020032806034205400_b4-0220e71","doi-asserted-by":"crossref","first-page":"1252","DOI":"10.1097\/00003246-199907000-00003","article-title":"Enteral tube feeding in the intensive care unit: factors impeding adequate delivery","volume":"27","author":"McClave","year":"1999","journal-title":"Crit Care Med"},{"issue":"9 suppl","key":"2020032806034205400_b5-0220e71","doi-asserted-by":"crossref","first-page":"S535","DOI":"10.1097\/01.CCM.0000279204.24648.44","article-title":"Feeding critically ill patients: what is the optimal amount of energy?","volume":"35","author":"Stapleton","year":"2007","journal-title":"Crit Care Med"},{"issue":"2","key":"2020032806034205400_b6-0220e71","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1177\/0884533610361605","article-title":"Early vs delayed enteral nutrition in critically ill medical patients","volume":"25","author":"Woo","year":"2010","journal-title":"Nutr Clin Pract"},{"issue":"24","key":"2020032806034205400_b7-0220e71","first-page":"628.e2","article-title":"Harris-Benedict equation for critically ill patients: are there differences with indirect calorimetry?","author":"Japur","year":"2009","journal-title":"J Crit Care"},{"issue":"2","key":"2020032806034205400_b8-0220e71","first-page":"129","article-title":"Energy expenditure in mechanical ventilation: is there an agreement between the Ireton-Jones equation and indirect calorimetry?","volume":"21","author":"dos Santos","year":"2009","journal-title":"Rev Bras Ter Intensiva"},{"issue":"6","key":"2020032806034205400_b9-0220e71","doi-asserted-by":"crossref","first-page":"809","DOI":"10.4065\/81.6.809","article-title":"Energy expenditure in hospitalized patients: implications for nutritional support","volume":"81","author":"Miles","year":"2006","journal-title":"Mayo Clin Proc"},{"issue":"2","key":"2020032806034205400_b10-0220e71","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1054\/clnu.2002.0526","article-title":"Measured versus estimated energy expenditure in mechanically ventilated critically ill patients","volume":"21","author":"Cheng","year":"2002","journal-title":"Clin Nutr"},{"issue":"5","key":"2020032806034205400_b11-0220e71","doi-asserted-by":"crossref","first-page":"727","DOI":"10.1016\/j.clnu.2006.03.011","article-title":"Hospitalized mechanically ventilated patients are at higher risk of enteral underfeeding than non-ventilated patients","volume":"25","author":"Kyle","year":"2006","journal-title":"Clin Nutr"},{"issue":"1","key":"2020032806034205400_b12-0220e71","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1097\/00003246-200101000-00002","article-title":"A prospective survey of nutritional support practices in intensive care unit patients: what is prescribed? what is delivered?","volume":"29","author":"De Jonghe","year":"2001","journal-title":"Crit Care Med"},{"issue":"1","key":"2020032806034205400_b13-0220e71","doi-asserted-by":"crossref","first-page":"53","DOI":"10.4037\/ajcc2008.17.1.53","article-title":"Evaluation of delivery of enteral nutrition in critically ill patients receiving mechanical ventilation","volume":"17","author":"O\u2019Meara","year":"2008","journal-title":"Am J Crit Care"},{"issue":"1","key":"2020032806034205400_b14-0220e71","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1017\/S0007114508986852","article-title":"What you think is not what they get: significant discrepancies between prescribed and administered doses of tube feeding","volume":"101","author":"van den Broek","year":"2009","journal-title":"Br J Nutr"},{"issue":"5","key":"2020032806034205400_b15-0220e71","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1177\/0148607103027005355","article-title":"Canadian clinical practice guidelines for nutrition support in mechanically ventilated, critically ill adult patients","volume":"27","author":"Heyland","year":"2003","journal-title":"J Parenter Enteral Nutr"},{"issue":"2","key":"2020032806034205400_b16-0220e71","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1054\/clnu.2002.0622","article-title":"Enteral nutrition practice in a surgical intensive care unit: what proportion of energy expenditure is delivered enterally?","volume":"22","author":"Engel","year":"2003","journal-title":"Clin Nutr"},{"issue":"10","key":"2020032806034205400_b17-0220e71","doi-asserted-by":"crossref","first-page":"1955","DOI":"10.1097\/00003246-200110000-00018","article-title":"Upper digestive intolerance during enteral nutrition in critically ill patients: frequency, risk factors, and complications","volume":"29","author":"Mentec","year":"2001","journal-title":"Crit Care Med"},{"issue":"3","key":"2020032806034205400_b18-0220e71","doi-asserted-by":"crossref","first-page":"221","DOI":"10.4037\/ajcc2004.13.3.221","article-title":"Outcomes associated with enteral tube feedings in a medical intensive care unit","volume":"13","author":"Elpern","year":"2004","journal-title":"Am J Crit Care"},{"issue":"1","key":"2020032806034205400_b19-0220e71","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/j.clnu.2005.08.013","article-title":"Enteral nutrition delivery and energy expenditure in medical intensive care patients","volume":"25","author":"Petros","year":"2006","journal-title":"Clin Nutr"},{"issue":"3","key":"2020032806034205400_b20-0220e71","doi-asserted-by":"crossref","first-page":"222","DOI":"10.4037\/ajcc2005.14.3.222","article-title":"Nutritional adequacy in patients receiving mechanical ventilation who are fed enterally","volume":"14","author":"O\u2019Leary-Kelley","year":"2005","journal-title":"Am J Crit Care"},{"issue":"4","key":"2020032806034205400_b21-0220e71","first-page":"331","article-title":"Nutrition support in intensive care unit: delivery versus requirements","volume":"18","author":"Teixeira","year":"2006","journal-title":"Rev Bras Ter Intensiva"},{"issue":"7\u20138","key":"2020032806034205400_b22-0220e71","doi-asserted-by":"crossref","first-page":"786","DOI":"10.1016\/j.nut.2004.11.014","article-title":"Variation in enteral nutrition delivery in mechanically ventilated patients","volume":"21","author":"Rice","year":"2005","journal-title":"Nutrition"},{"issue":"1","key":"2020032806034205400_b23-0220e71","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1590\/S0041-87812003000100003","article-title":"Effects of continuous versus bolus infusion of enteral nutrition in critical patients","volume":"58","author":"Serpa","year":"2003","journal-title":"Rev Hosp Clin Fac Med"},{"issue":"1","key":"2020032806034205400_b24-0220e71","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1097\/01.ta.0000249294.58703.11","article-title":"Prospective randomized control trial of intermittent versus continuous gastric feeds for critically ill trauma patients","volume":"63","author":"MacLeod","year":"2007","journal-title":"J Trauma"},{"issue":"2","key":"2020032806034205400_b25-0220e71","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1111\/j.1365-2702.2006.01262.x","article-title":"Nutrition of the critically ill patient and effects of implementing a nutritional support algorithm in ICU","volume":"15","author":"Woien","year":"2006","journal-title":"J Clin Nurs"},{"issue":"4","key":"2020032806034205400_b26-0220e71","doi-asserted-by":"crossref","first-page":"376","DOI":"10.1590\/S0103-507X2009000400007","article-title":"Enteral nutritional therapy: application of quality indicators","volume":"21","author":"Cartolano","year":"2009","journal-title":"Rev Bras Ter Intensiva"},{"issue":"3","key":"2020032806034205400_b27-0220e71","first-page":"270","article-title":"Gastrointestinal complications and protein-calorie adequacy in intensive care unit enteral nutrition patients","volume":"22","author":"de Oliveira","year":"2010","journal-title":"Rev Bras Ter Intensiva"},{"issue":"4","key":"2020032806034205400_b28-0220e71","first-page":"1","article-title":"Optimal nutrition during the period of mechanical ventilation decreases mortality in critically ill, long-term acute female patients: a prospective observational cohort study","volume":"13","author":"van Schijndel","year":"2009","journal-title":"Crit Care"},{"key":"2020032806034205400_b29-0220e71","doi-asserted-by":"publisher","DOI":"10.1016\/j.eimc.2012.11.010","article-title":"Eradication of a nosocomial outbreak of multidrug-resistant Acinetobacter baumannii infections after adjusting nursing workloads and reinforcing specific precautions","author":"Bou","year":"2013","journal-title":"Enferm Infecc Microbiol Clin"},{"issue":"2","key":"2020032806034205400_b30-0220e71","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1016\/j.jhin.2011.11.014","article-title":"Understaffing, overcrowding, inappropriate nurse:ventilated patient ratio and nosocomial infections: which parameter is the best reflection of deficits?","volume":"80","author":"Schwab","year":"2012","journal-title":"J Hosp Infect"},{"key":"2020032806034205400_b31-0220e71","doi-asserted-by":"crossref","first-page":"49","DOI":"10.2147\/JMDH.S9699","article-title":"Relationship between nursing workloads and patient safety incidents","volume":"3","author":"Nishizaki","year":"2010","journal-title":"J Multidiscip Healthc"},{"issue":"10","key":"2020032806034205400_b32-0220e71","doi-asserted-by":"crossref","first-page":"1740","DOI":"10.1007\/s00134-007-0712-1","article-title":"Gastric feed intolerance is not increased in critically ill patients with type II diabetes mellitus","volume":"33","author":"Nguyen","year":"2007","journal-title":"Intensive Care Med"},{"issue":"6","key":"2020032806034205400_b33-0220e71","doi-asserted-by":"crossref","first-page":"809","DOI":"10.4065\/81.6.809","article-title":"Energy expenditure in hospitalized patients: Implications for nutritional support","volume":"81","author":"Miles","year":"2006","journal-title":"Mayo Clin Proc"},{"issue":"12","key":"2020032806034205400_b34-0220e71","doi-asserted-by":"crossref","first-page":"2264","DOI":"10.1097\/00003246-200112000-00005","article-title":"Early enteral nutrition in acutely ill patients: a systematic review","volume":"29","author":"Marik","year":"2001","journal-title":"Crit Care Med"},{"issue":"12","key":"2020032806034205400_b35-0220e71","doi-asserted-by":"crossref","first-page":"2018","DOI":"10.1007\/s00134-009-1664-4","article-title":"Early enteral nutrition, provided within 24 h of injury or intensive care unit admission, significantly reduces mortality in critically ill patients: a meta-analysis of randomised controlled trials","volume":"35","author":"Doig","year":"2009","journal-title":"Intensive Care Med"},{"issue":"11","key":"2020032806034205400_b36-0220e71","doi-asserted-by":"crossref","first-page":"2525","DOI":"10.1097\/00003246-199911000-00033","article-title":"Prospective, randomized, controlled trial to determine the effect of early enhanced enteral nutrition on clinical outcome in mechanically ventilated patients suffering head injury","volume":"27","author":"Taylor","year":"1999","journal-title":"Crit Care Med"},{"issue":"3","key":"2020032806034205400_b37-0220e71","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1177\/0148607102026003174","article-title":"Early versus late enteral feeding of mechanically ventilated patients: results of a clinical trial","volume":"26","author":"Ibrahim","year":"2002","journal-title":"J Parenter Enteral Nutr"},{"issue":"5","key":"2020032806034205400_b38-0220e71","doi-asserted-by":"crossref","first-page":"967","DOI":"10.1097\/CCM.0b013e31820a905a","article-title":"Randomized trial of initial trophic versus full-energy enteral nutrition in mechanically ventilated patients with acute respiratory failure","volume":"39","author":"Rice","year":"2011","journal-title":"Crit Care Med"},{"key":"2020032806034205400_b39-0220e71","doi-asserted-by":"crossref","first-page":"967","DOI":"10.1097\/CCM.0b013e31820a905a","article-title":"Randomized trial of initial trophic versus full-energy enteral nutrition in mechanically ventilated patients with acute respiratory failure","volume":"39","author":"Rice","year":"2011","journal-title":"Crit Care Med"},{"issue":"23","key":"2020032806034205400_b40-0220e71","doi-asserted-by":"crossref","first-page":"2013","DOI":"10.1001\/jama.280.23.2013","article-title":"Total parenteral nutrition in the critically ill patient: a meta-analysis","volume":"280","author":"Heyland","year":"1998","journal-title":"JAMA"},{"issue":"4","key":"2020032806034205400_b41-0220e71","doi-asserted-by":"crossref","first-page":"534","DOI":"10.1093\/ajcn\/74.4.534","article-title":"Enteral compared with parenteral nutrition: a meta-analysis","volume":"74","author":"Braunschweig","year":"2001","journal-title":"Am J Clin Nutr"},{"issue":"10","key":"2020032806034205400_b42-0220e71","doi-asserted-by":"crossref","first-page":"843","DOI":"10.1016\/j.nut.2004.06.003","article-title":"Does enteral nutrition compared to parenteral nutrition result in better outcomes in critically ill adult patients? A systematic review of the literature","volume":"20","author":"Gramlich","year":"2004","journal-title":"Nutrition"},{"issue":"8","key":"2020032806034205400_b43-0220e71","doi-asserted-by":"crossref","first-page":"1666","DOI":"10.1007\/s00134-004-2345-y","article-title":"Combination enteral and parenteral nutrition in critically ill patients: harmful or beneficial? A systematic review of the evidence","volume":"30","author":"Dhaliwal","year":"2004","journal-title":"Intensive Care Med"},{"issue":"1","key":"2020032806034205400_b44-0220e71","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1097\/01.CCM.0000150960.36228.C0","article-title":"A metaanalysis of treatment outcomes of early enteral versus early parenteral nutrition in hospitalized patients","volume":"33","author":"Peter","year":"2005","journal-title":"Crit Care Med"},{"issue":"1","key":"2020032806034205400_b45-0220e71","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1007\/s00134-004-2511-2","article-title":"Parenteral vs. enteral nutrition in the critically ill patient: a meta-analysis of trials using the intention to treat principle","volume":"31","author":"Simpson","year":"2005","journal-title":"Intensive Care Med"},{"issue":"2","key":"2020032806034205400_b46-0220e71","doi-asserted-by":"crossref","first-page":"412","DOI":"10.1111\/j.1572-0241.2006.01024.x","article-title":"Does enteral nutrition affect clinical outcome? A systematic review of the randomized trials","volume":"102","author":"Koretz","year":"2007","journal-title":"Am J Gastroenterol"},{"issue":"6","key":"2020032806034205400_b47-0220e71","doi-asserted-by":"crossref","first-page":"506","DOI":"10.1056\/NEJMoa1102662","article-title":"Early versus late parenteral nutrition in critically ill adults","volume":"365","author":"Casaer","year":"2011","journal-title":"N Engl J Med"},{"issue":"2","key":"2020032806034205400_b48-0220e71","first-page":"197","article-title":"Multicentre, cluster-randomized clinical trial of algorithms for critical-care enteral and parenteral therapy (ACCEPT)","volume":"170","author":"Martin","year":"2004","journal-title":"CMAJ"},{"issue":"23","key":"2020032806034205400_b49-0220e71","doi-asserted-by":"crossref","first-page":"2731","DOI":"10.1001\/jama.2008.826","article-title":"Effect of evidence-based feeding guidelines on mortality of critically ill adults: a cluster randomized controlled trial","volume":"300","author":"Doig","year":"2008","journal-title":"JAMA"}],"container-title":["American Journal of Critical Care"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/aacnjournals.org\/ajcconline\/article-pdf\/22\/6\/e71\/92282\/e71.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"http:\/\/aacnjournals.org\/ajcconline\/article-pdf\/22\/6\/e71\/92282\/e71.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,8,7]],"date-time":"2020-08-07T07:03:54Z","timestamp":1596783834000},"score":1,"resource":{"primary":{"URL":"https:\/\/aacnjournals.org\/ajcconline\/article\/22\/6\/e71\/3933\/Nurse-to-Bed-Ratio-and-Nutrition-Support-in"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,11,1]]},"references-count":49,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2013,11,1]]}},"URL":"https:\/\/doi.org\/10.4037\/ajcc2013610","relation":{},"ISSN":["1062-3264","1937-710X"],"issn-type":[{"value":"1062-3264","type":"print"},{"value":"1937-710X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,11,1]]}}}