{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T14:50:27Z","timestamp":1787928627525,"version":"build-2784847793"},"reference-count":58,"publisher":"AACN Publishing","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2020,3,1]]},"abstract":"<jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Physical restraints are frequently used for intensive care patients and are associated with substantial morbidity. The effects of common evidence-based critical care interventions on use of physical restraints remain unclear.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Objective<\/jats:title>\n                  <jats:p>To identify independent predictors of new-onset use of physical restraints in critically ill adults.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>Secondary analysis of a prospective cohort study involving 5 adult intensive care units in a tertiary care medical center in the United States. Use of physical restraints was determined via daily in-person assessments and medical record review. Mixed-effects logistic regression analysis was used to examine factors associated with new-onset use of physical restraints, adjusting for covariates and within-subject correlation among intensive care unit days.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>Of 145 patients who were free of physical restraints within 48 hours of intensive care unit admission, 24 (16.6%) had restraints newly applied during their stay. In adjusted models, delirium (odds ratio [OR], 5.09; 95% CI, 1.83-14.14), endotracheal tube presence (OR, 3.47; 95% CI, 1.22-9.86), and benzodiazepine administration (OR, 3.17; 95% CI, 1.28-7.81) significantly increased the odds of next-day use of physical restraints. Tracheostomy was associated with significantly lowered odds of next-day restraint use (OR, 0.13; 95% CI, 0.02-0.73). Compared with patients with a target sedation level, patients who were in a coma (OR, 2.56; 95% CI, 0.80-8.18) or deeply sedated (OR, 2.53; 95% CI, 0.91-7.08) had higher odds of next-day use of physical restraints, and agitated patients (OR, 0.08; 95% CI, 0.00-2.07) were less likely to experience restraint use.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>Several potentially modifiable risk factors are associated with next-day use of physical restraints.<\/jats:p>\n               <\/jats:sec>","DOI":"10.4037\/ajcc2020361","type":"journal-article","created":{"date-parts":[[2020,5,7]],"date-time":"2020-05-07T22:02:07Z","timestamp":1588888927000},"page":"92-102","source":"Crossref","is-referenced-by-count":23,"title":["Predictors of New-Onset Physical Restraint Use in Critically Ill Adults"],"prefix":"10.4037","volume":"29","author":[{"given":"Thomas N.","family":"Lawson","sequence":"first","affiliation":[{"name":"Thomas N. Lawson is a doctoral student at The Ohio State University College of Nursing and an acute care nurse practitioner at The Ohio State University Wexner Medical Center, Columbus, Ohio."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alai","family":"Tan","sequence":"first","affiliation":[{"name":"Alai Tan is a research associate professor, The Ohio State University College of Nursing."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susan E.","family":"Thrane","sequence":"first","affiliation":[{"name":"Susan E. Thrane is an assistant professor, The Ohio State University College of Nursing."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mary Beth","family":"Happ","sequence":"first","affiliation":[{"name":"Mary Beth Happ is a professor and Associate Dean for Research and Innovation, The Ohio State University College of Nursing."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lorraine C.","family":"Mion","sequence":"first","affiliation":[{"name":"Lorraine C. Mion is a professor, The Ohio State University College of Nursing and a nurse scientist, The Ohio State University Wexner Medical Center."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Judith","family":"Tate","sequence":"first","affiliation":[{"name":"Judith Tate is an assistant professor, The Ohio State University College of Nursing and a nurse scientist, The Ohio State University Wexner Medical Center."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michele C.","family":"Balas","sequence":"first","affiliation":[{"name":"Michele C. 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