{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T09:07:40Z","timestamp":1785575260975,"version":"3.56.0"},"reference-count":22,"publisher":"AACN Publishing","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,11,1]]},"abstract":"<jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Weaning from venoarterial extracorporeal membrane oxygenation (VA-ECMO) support fails in 30% to 70% of patients.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Objective<\/jats:title>\n                  <jats:p>To explore the utility of echocardiographic parameters in predicting successful disconnection from VA-ECMO.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>Patients receiving VA-ECMO in a referral hospital were included. The relationships between echocardiographic parameters during the weaning trial and weaning success (survival &amp;gt; 24 hours after VA-ECMO explant and no death from cardiogenic shock, heart failure, or cardiac arrest during the hospital stay) and survival were evaluated.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>Of 85 patients included, 61% had successful weaning. Parameters significantly related to weaning success were higher left ventricular ejection fraction (LVEF; 40% in patients with weaning success vs 30% in patients with weaning failure, P = .01), left ventricular outflow tract velocity time integral (15 cm vs 11 cm, P = .01), aortic valve opening in every cycle (98% vs 91% of patients, P = .01), and normal qualitative right ventricular function (60% vs 42% of patients, P = .02). The LVEF remained as an independent predictor of weaning success (hazard ratio, 0.938; 95% CI, 0.888-0.991; P = .02). An LVEF &amp;gt;33.4% was the optimal cutoff value to discriminate patients with successful weaning (area under the curve, 0.808; sensitivity, 93%; specificity, 72%) and was related to higher survival at discharge (60% vs 20%, P &amp;lt; .001).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>Among weaning trial echocardiographic parameters, LVEF was the only independent predictor of successful VA-ECMO weaning. An LVEF &amp;gt;33.4% was the optimal cutoff value to discriminate patients with successful weaning and was related to final survival.<\/jats:p>\n               <\/jats:sec>","DOI":"10.4037\/ajcc2022588","type":"journal-article","created":{"date-parts":[[2022,11,1]],"date-time":"2022-11-01T02:07:43Z","timestamp":1667268463000},"page":"483-493","source":"Crossref","is-referenced-by-count":8,"title":["Echocardiographic Prediction of Successful Weaning From Venoarterial Extracorporeal Membrane Oxygenation"],"prefix":"10.4037","volume":"31","author":[{"given":"Marta","family":"Alonso-Fernandez-Gatta","sequence":"first","affiliation":[{"name":"Marta Alonso-Fernandez-Gatta is a cardiologist at University Hospital of Salamanca-Instituto de Investigaci\u00f3n Biom\u00e9dica de Salamanca (IBSAL), Salamanca, Spain and takes part in the Centro de Investigaci\u00f3n en Red de Enfermedades Cardio vasculares (CIBER-CV), Instituto de Salud Carlos III, Madrid, Spain."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Soraya","family":"Merchan-Gomez","sequence":"additional","affiliation":[{"name":"Soraya Merchan-Gomez is a cardiologist at University Hospital of Salamanca-IBSAL and takes part in CIBER-CV, Instituto de Salud Carlos III."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miryam","family":"Gonzalez-Cebrian","sequence":"additional","affiliation":[{"name":"Miryam Gonzalez-Cebrian is a nursing supervisor, Cardiology Department, University Hospital of Salamanca-IBSAL."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alejandro","family":"Diego-Nieto","sequence":"additional","affiliation":[{"name":"Alejandro Diego-Nieto is a cardiologist at University Hospital of Salamanca-IBSAL and takes part in CIBER-CV, Instituto de Salud Carlos III."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Javier","family":"Gonzalez-Martin","sequence":"additional","affiliation":[{"name":"Javier Gonzalez-Martin is a cardiologist, University Hospital of Salamanca-IBSAL."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ines","family":"Toranzo-Nieto","sequence":"additional","affiliation":[{"name":"Ines Toranzo-Nieto is a cardiologist at University Hospital of Salamanca-IBSAL and takes part in CIBER-CV, Instituto de Salud Carlos III."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alfredo","family":"Barrio","sequence":"additional","affiliation":[{"name":"Alfredo Barrio is a cardiologist at University Hospital of Salamanca-IBSAL and takes part in CIBER-CV, Instituto de Salud Carlos III."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francisco","family":"Martin-Herrero","sequence":"additional","affiliation":[{"name":"Francisco Martin-Herrero is a cardiologist at University Hospital of Salamanca-IBSAL and takes part in CIBER-CV, Instituto de Salud Carlos III."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pedro L.","family":"Sanchez","sequence":"additional","affiliation":[{"name":"Pedro L. 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