{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,7]],"date-time":"2026-05-07T12:43:52Z","timestamp":1778157832271,"version":"3.51.4"},"reference-count":24,"publisher":"AACN Publishing","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,11,1]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>The ABCDEF bundle improves outcomes of patients in the intensive care unit, but its adoption remains low worldwide due to multiple implementation barriers. Interprofessional simulation training may help facilitate ABCDEF bundle implementation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To evaluate the feasibility of an interprofessional simulation-based training to facilitate ABCDEF bundle implementation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A 90-minute interprofessional training program was designed and implemented. Each simulation started with a deeply sedated patient receiving mechanical ventilation, and interprofessional learners assessed sedation and delirium, conducted spontaneous awakening trials, managed delirium and agitation using multicomponent nonpharmacologic interventions, and mobilized the patient out of bed. Feasibility of the training was evaluated by using a participant survey on simulation experiences and measuring participants\u2019 attitudes toward ABCDEF bundle implementation before and after training.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Sixteen clinicians from different disciplines and with various years of intensive care unit experience participated. Most participants agreed that the simulation was realistic, relevant, important to practice, and stress provoking and would improve their clinical performance. After the training, participants reported increased comfort and willingness to perform spontaneous awakening trials, comfort in managing patients with delirium and agitation, and confidence in collaborating with other team members to mobilize patients receiving mechanical ventilation out of bed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The interprofessional simulation training was feasible and well accepted and increased positive attitudes toward ABCDEF bundle implementation.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4037\/ajcc2025955","type":"journal-article","created":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T02:03:31Z","timestamp":1761962611000},"page":"463-468","source":"Crossref","is-referenced-by-count":1,"title":["Interprofessional Simulation-Based Training to Facilitate ABCDEF Bundle Implementation"],"prefix":"10.4037","volume":"34","author":[{"given":"Mikita","family":"Fuchita","sequence":"first","affiliation":[{"name":"Mikita Fuchita is an assistant professor, Department of Anesthesiology, Division of Critical Care, University of Colorado Anschutz Medical Campus, Aurora."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lorel","family":"Huber","sequence":"additional","affiliation":[{"name":"Lorel Huber is an assistant professor, Department of Pediatric Critical Care Medicine, Children\u2019s Hospital Colorado, Aurora."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Deena","family":"Costa","sequence":"additional","affiliation":[{"name":"Deena Costa is an associate professor, Yale School of Nursing, and an associate professor, Department of Internal Medicine, Section of Pulmonary, Critical Care, and Sleep Medicine, Yale School of Medicine, New Haven, Connecticut."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anuj B.","family":"Mehta","sequence":"additional","affiliation":[{"name":"Anuj B. Mehta is an associate professor, Department of Medicine, Pulmonary Sciences and Critical Care Medicine, University of Colorado Anschutz Medical Campus, Aurora, and an associate professor, Department of Medicine, Pulmonary, and Critical Care Medicine, Denver Health and Hospital Authority, Denver."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dan","family":"Matlock","sequence":"additional","affiliation":[{"name":"Dan Matlock is a professor, Division of Geriatrics, Department of Medicine, University of Colorado School of Medicine, Aurora, and a professor, VA Eastern Colorado Geriatric Research Education and Clinical Center, Denver."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ryan","family":"Good","sequence":"additional","affiliation":[{"name":"Ryan Good is an associate professor, Department of Pediatric Critical Care Medicine, Children\u2019s Hospital Colorado, Aurora."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2471","reference":[{"issue":"8","key":"2025103122032985400_b1-0340463","doi-asserted-by":"crossref","first-page":"1227","DOI":"10.1097\/CCM.0000000000005125","article-title":"ICU survivorship\u2014the relationship of delirium, sedation, dementia, and acquired weakness","volume":"49","author":"Mart","year":"2021","journal-title":"Crit Care Med"},{"issue":"2","key":"2025103122032985400_b2-0340463","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1097\/CCM.0000000000002175","article-title":"The ABCDEF bundle: science and philosophy of how ICU Liberation serves patients and families","volume":"45","author":"Ely","year":"2017","journal-title":"Crit Care Med"},{"issue":"1","key":"2025103122032985400_b3-0340463","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1097\/CCM.0000000000003482","article-title":"Caring for critically ill patients with the ABCDEF bundle: results of the ICU Liberation Collaborative in over 15,000 adults","volume":"47","author":"Pun","year":"2019","journal-title":"Crit Care Med"},{"issue":"5","key":"2025103122032985400_b4-0340463","doi-asserted-by":"crossref","first-page":"1024","DOI":"10.1097\/CCM.0000000000000129","article-title":"Effectiveness and safety of the awakening and breathing coordination, delirium monitoring\/management, and early exercise\/mobility bundle","volume":"42","author":"Balas","year":"2014","journal-title":"Crit Care Med"},{"issue":"1","key":"2025103122032985400_b5-0340463","doi-asserted-by":"crossref","first-page":"46","DOI":"10.4037\/ccn2019927","article-title":"Common challenges to effective ABCDEF bundle implementation: the ICU Liberation Campaign Experience","volume":"39","author":"Balas","year":"2019","journal-title":"Crit Care Nurse"},{"issue":"2","key":"2025103122032985400_b6-0340463","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1016\/j.chest.2017.03.054","article-title":"Identifying barriers to delivering the awakening and breathing coordination, delirium, and early exercise\/mobility bundle to minimize adverse outcomes for mechanically ventilated patients: a systematic review","volume":"152","author":"Costa","year":"2017","journal-title":"Chest"},{"issue":"9 suppl 1","key":"2025103122032985400_b7-0340463","doi-asserted-by":"crossref","first-page":"S116","DOI":"10.1097\/CCM.0b013e3182a17064","article-title":"Implementing the awakening and breathing coordination, delirium monitoring\/management, and early exercise\/mobility bundle into everyday care: opportunities, challenges, and lessons learned for implementing the ICU pain, agitation, and delirium guidelines","volume":"41","author":"Balas","year":"2013","journal-title":"Crit Care Med"},{"issue":"1","key":"2025103122032985400_b8-0340463","doi-asserted-by":"crossref","first-page":"54","DOI":"10.4037\/ajcc2022768","article-title":"Effects of a national quality improvement collaborative on ABCDEF bundle implementation","volume":"31","author":"Balas","year":"2022","journal-title":"Am J Crit Care"},{"key":"2025103122032985400_b9-0340463","doi-asserted-by":"crossref","first-page":"735860","DOI":"10.3389\/fmed.2021.735860","article-title":"Implementation of the ABCDEF bundle for critically ill ICU patients during the COVID-19 pandemic: a multi-national 1-day point prevalence study","volume":"8","author":"Liu","year":"2021","journal-title":"Front Med (Lausanne)"},{"issue":"6","key":"2025103122032985400_b10-0340463","doi-asserted-by":"crossref","first-page":"772","DOI":"10.1111\/nicc.12740","article-title":"The impact of ABCDE bundle implementation on patient outcomes: a nationwide cohort study","volume":"27","author":"Frade-Mera","year":"2022","journal-title":"Nurs Crit Care"},{"issue":"5","key":"2025103122032985400_b11-0340463","doi-asserted-by":"crossref","first-page":"1308","DOI":"10.1097\/CCM.0000000000000184","article-title":"Why the reluctance to meaningfully mobilize ventilated patients? \u201cThe answer my friend is blowin\u2019 in the wind\u201d","volume":"42","author":"Clemmer","year":"2014","journal-title":"Crit Care Med"},{"issue":"10 suppl","key":"2025103122032985400_b12-0340463","doi-asserted-by":"crossref","first-page":"S429","DOI":"10.1097\/CCM.0b013e3181b6e227","article-title":"Culture of early mobility in mechanically ventilated patients","volume":"37","author":"Bailey","year":"2009","journal-title":"Crit Care Med"},{"issue":"6","key":"2025103122032985400_b13-0340463","doi-asserted-by":"crossref","first-page":"980","DOI":"10.1097\/CCM.0000000000003067","article-title":"Interprofessional care and teamwork in the ICU","volume":"46","author":"Donovan","year":"2018","journal-title":"Crit Care Med"},{"issue":"8","key":"2025103122032985400_b14-0340463","doi-asserted-by":"publisher","first-page":"e0169","DOI":"10.1097\/CCE.0000000000000169","article-title":"Organizational characteristics associated with ICU Liberation (ABCDEF) bundle implementation by adult ICUs in Michigan","volume":"2","author":"Barr","year":"2020","journal-title":"Crit Care Explor"},{"issue":"9 suppl 1","key":"2025103122032985400_b15-0340463","doi-asserted-by":"publisher","first-page":"S128","DOI":"10.1097\/CCM.0b013e3182a2c2b1","article-title":"Contextual issues influencing implementation and outcomes associated with an integrated approach to managing pain, agitation, and delirium in adult ICUs","volume":"41","author":"Carrothers","year":"2013","journal-title":"Crit Care Med"},{"issue":"2","key":"2025103122032985400_b16-0340463","doi-asserted-by":"publisher","first-page":"171","DOI":"10.1097\/CCM.0000000000002149","article-title":"Improving hospital survival and reducing brain dysfunction at seven California community hospitals: implementing PAD guidelines via the ABCDEF bundle in 6,064 patients","volume":"45","author":"Barnes-Daly","year":"2017","journal-title":"Crit Care Med"},{"issue":"2","key":"2025103122032985400_b17-0340463","doi-asserted-by":"publisher","first-page":"157","DOI":"10.1097\/CNQ.0000000000000448","article-title":"A multidisciplinary approach to increase compliance with spontaneous awakening trials and spontaneous breathing trials in the medical intensive care unit","volume":"46","author":"Jones","year":"2023","journal-title":"Crit Care Nurs Q"},{"issue":"25","key":"2025103122032985400_b18-0340463","doi-asserted-by":"publisher","first-page":"e29503","DOI":"10.1097\/MD.0000000000029503","article-title":"A review on the evolution of simulation-based training to help build a safer future","volume":"101","author":"Bienstock","year":"2022","journal-title":"Medicine (Baltimore)"},{"key":"2025103122032985400_b19-0340463","doi-asserted-by":"crossref","first-page":"355","DOI":"10.2147\/JMDH.S500890","article-title":"Improving critical care teamwork: simulation-based interprofessional training for enhanced communication and safety","volume":"18","author":"Sung","year":"2025","journal-title":"J Multidiscip Healthc"},{"key":"2025103122032985400_b20-0340463","doi-asserted-by":"crossref","first-page":"S5","DOI":"10.1016\/j.ecns.2016.09.005","article-title":"INACSL Standards of Best Practice: SimulationSM simulation design","volume":"12","author":"INACSL Standards Committee","year":"2016","journal-title":"Clin Simul Nurs"},{"issue":"7","key":"2025103122032985400_b21-0340463","doi-asserted-by":"crossref","first-page":"1370","DOI":"10.1097\/00003246-200107000-00012","article-title":"Evaluation of delirium in critically ill patients: validation of the Confusion Assessment Method for the intensive care unit (CAM-ICU)","volume":"29","author":"Ely","year":"2001","journal-title":"Crit Care Med"},{"issue":"9607","key":"2025103122032985400_b22-0340463","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1016\/S0140-6736(08)60105-1","article-title":"Efficacy and safety of a paired sedation and ventilator weaning protocol for mechanically ventilated patients in intensive care (awakening and breathing controlled trial): a randomised controlled trial","volume":"371","author":"Girard","year":"2008","journal-title":"Lancet"},{"issue":"9","key":"2025103122032985400_b23-0340463","doi-asserted-by":"publisher","first-page":"e825","DOI":"10.1097\/CCM.0000000000003299","article-title":"Clinical practice guidelines for the prevention and management of pain, agitation\/sedation, delirium, immobility, and sleep disruption in adult patients in the ICU","volume":"46","author":"Devlin","year":"2018","journal-title":"Crit Care Med"},{"issue":"7","key":"2025103122032985400_b24-0340463","doi-asserted-by":"crossref","first-page":"945","DOI":"10.1016\/j.resuscitation.2014.02.025","article-title":"Pediatric resident resuscitation skills improve after \u201crapid cycle deliberate practice\u201d training","volume":"85","author":"Hunt","year":"2014","journal-title":"Resuscitation"}],"container-title":["American Journal of Critical Care"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/aacnjournals.org\/ajcconline\/article-pdf\/34\/6\/463\/166860\/463.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/aacnjournals.org\/ajcconline\/article-pdf\/34\/6\/463\/166860\/463.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T02:03:33Z","timestamp":1761962613000},"score":1,"resource":{"primary":{"URL":"https:\/\/aacnjournals.org\/ajcconline\/article\/34\/6\/463\/32875\/Interprofessional-Simulation-Based-Training-to"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,11,1]]},"references-count":24,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2025,11,1]]}},"URL":"https:\/\/doi.org\/10.4037\/ajcc2025955","relation":{},"ISSN":["1062-3264","1937-710X"],"issn-type":[{"value":"1062-3264","type":"print"},{"value":"1937-710X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,11,1]]}}}