{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:40:08Z","timestamp":1748738408983,"version":"3.41.0"},"reference-count":23,"publisher":"AACN Publishing","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,6,1]]},"abstract":"<jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>After terminal extubation, more than 30% of patients experience a period of persistent dyspnea. Practices regarding terminal extubation at the end of life vary widely, and evidence for practice superiority is lacking. Critical care nurses are often tasked with making intervention decisions.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Local Problem<\/jats:title>\n                  <jats:p>At a 368-bed acute care hospital, nurses reported a lack of training on managing end-of-life symptoms associated with terminal extubation and the need for a standardized protocol to guide assessment and interventions. The aim of this study was to examine how use of an evidence-based terminal extubation protocol affects bedside nursing practice and clinician experience.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>An interprofessional work group conducted a needs assessment, developed a terminal extubation protocol, provided education, and implemented the protocol. The protocol included the use of the Respiratory Distress Observation Scale as a new tool to evaluate patient distress and specified reassessment frequency, anticipated dose calculation, titration parameters, and steps for weaning. The work group examined the use of continuous infusion, bolus dosing, titration, and interventions before and after protocol implementation.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>Findings after protocol implementation included an increased reliance on bolus dosing and titration for evolving symptoms, greater use of evidence-based end-of-life medications, improved documentation demonstrating calculation of anticipatory doses, and an average time from start of process to extubation of approximately 21 minutes. Clinicians reported that use of the protocol improved symptom management.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>A terminal extubation protocol can provide critical care nurses with an objective tool to guide assessment and interventions. Effective protocol implementation requires strong interprofessional collaboration.<\/jats:p>\n               <\/jats:sec>","DOI":"10.4037\/ccn2025828","type":"journal-article","created":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:03:31Z","timestamp":1748736211000},"page":"47-55","source":"Crossref","is-referenced-by-count":0,"title":["Impact of Guided Interventions on Terminal Extubation: A Pilot Project"],"prefix":"10.4037","volume":"45","author":[{"given":"Rachel M.","family":"Sabolish","sequence":"first","affiliation":[{"name":"Rachel M. 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