{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,17]],"date-time":"2026-06-17T08:54:44Z","timestamp":1781686484893,"version":"3.54.5"},"reference-count":25,"publisher":"Norwegian Medical Association","issue":"10","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Tidsskr Nor Legeforen","Tidsskriftet"],"DOI":"10.4045\/tidsskr.20.0730","type":"journal-article","created":{"date-parts":[[2021,6,29]],"date-time":"2021-06-29T03:43:13Z","timestamp":1624938193000},"source":"Crossref","is-referenced-by-count":1,"title":["En mann i 40-\u00e5rene med rask forverring av kronisk fots\u00e5r"],"prefix":"10.4045","volume":"141","author":[{"given":"Thomas Tetens","family":"Moe","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcus","family":"G\u00fcrgen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erling","family":"Undersrud","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rune","family":"Klepp","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Harald","family":"Sola","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2479","published-online":{"date-parts":[[2021,6,28]]},"reference":[{"key":"ref=1","doi-asserted-by":"crossref","unstructured":"Sedlin\u00a0E, Flemming\u00a0J. Epidermoid carcinoma arising in chronic osteomyelitis foci. J Bone Joint Surg 1963; 45: 827\u201338. Crossref: http:\/\/dx.doi.org\/10.2106%2F00004623-196345040-00017","DOI":"10.2106\/00004623-196345040-00017"},{"key":"ref=2","doi-asserted-by":"crossref","unstructured":"Hannah\u00a0CE, Weig\u00a0EA, Collier\u00a0S et al. Verrucous carcinoma: An unexpected finding arising from a burn scar. JAAD Case Rep 2019; 5: 225\u20137. PubMed: http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=30809566&dopt=Abstract, Crossref: http:\/\/dx.doi.org\/10.1016%2Fj.jdcr.2018.12.006","DOI":"10.1016\/j.jdcr.2018.12.006"},{"key":"ref=3","unstructured":"Elder DE, Massi D, Scolyer RA et al. WHO Classification of Skin Tumours 4th Edition. IARC Publication, 2018."},{"key":"ref=4","unstructured":"Calonje E, Brenn T, Lazar AJ et al. McKee's Pathology of the Skin 5th Edition. Elsevier, 2019."},{"key":"ref=5","unstructured":"Eighth Edition of the American Joint Committee on Cancer Staging Guidelines. American Joint Committee on Cancer Staging, 1997."},{"key":"ref=6","unstructured":"Copcu\u00a0E. Marjolin's ulcer: a preventable complication of burns? Plast Reconstr Surg 2009; 124: 156e\u201364e. PubMed: http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=19568055&dopt=Abstract, Crossref: http:\/\/dx.doi.org\/10.1097%2FPRS.0b013e3181a8082e"},{"key":"ref=7","doi-asserted-by":"crossref","unstructured":"Bazali\u0144ski\u00a0D, Przybek-Mita\u00a0J, Bara\u0144ska\u00a0B et al. Marjolin's ulcer in chronic wounds - review of available literature. Contemp Oncol (Pozn) 2017; 21: 197\u2013202. PubMed: http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=29180925&dopt=Abstract, Crossref: http:\/\/dx.doi.org\/10.5114%2Fwo.2017.70109","DOI":"10.5114\/wo.2017.70109"},{"key":"ref=8","doi-asserted-by":"crossref","unstructured":"Kerr-Valentic\u00a0MA, Samimi\u00a0K, Rohlen\u00a0BH et al. Marjolin's ulcer: modern analysis of an ancient problem. Plast Reconstr Surg 2009; 123: 184\u201391. PubMed: http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=19116552&dopt=Abstract, Crossref: http:\/\/dx.doi.org\/10.1097%2FPRS.0b013e3181904d86","DOI":"10.1097\/PRS.0b013e3181904d86"},{"key":"ref=9","doi-asserted-by":"crossref","unstructured":"Baldursson\u00a0BT, Hedblad\u00a0MA, Beitner\u00a0H et al. Squamous cell carcinoma complicating chronic venous leg ulceration: a study of the histopathology, course and survival in 25 patients. Br J Dermatol 1999; 140: 1148\u201352. PubMed: http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=10354087&dopt=Abstract, Crossref: http:\/\/dx.doi.org\/10.1046%2Fj.1365-2133.1999.02879.x","DOI":"10.1046\/j.1365-2133.1999.02879.x"},{"key":"ref=10","doi-asserted-by":"crossref","unstructured":"Yon\u00a0JR, Son\u00a0JD, Fredericks\u00a0C et al. Marjolin's ulcer in chronic hidradenitis suppurativa: A rare complication of an often neglected disease. J Burn Care Res 2017; 38: 121\u20134. PubMed: http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=27380120&dopt=Abstract, Crossref: http:\/\/dx.doi.org\/10.1097%2FBCR.0000000000000399","DOI":"10.1097\/BCR.0000000000000399"},{"key":"ref=11","unstructured":"Chalya\u00a0PL, Mabula\u00a0JB, Rambau\u00a0P et al. Marjolin's ulcers at a university teaching hospital in Northwestern Tanzania: a retrospective review of 56 cases. World J Surg Oncol 2012; 10: 38. PubMed: http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=22336561&dopt=Abstract, Crossref: http:\/\/dx.doi.org\/10.1186%2F1477-7819-10-38"},{"key":"ref=12","doi-asserted-by":"crossref","unstructured":"Kowal-Vern\u00a0A, Criswell\u00a0BK. Burn scar neoplasms: a literature review and statistical analysis. Burns 2005; 31: 403\u201313. PubMed: http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=15896501&dopt=Abstract, Crossref: http:\/\/dx.doi.org\/10.1016%2Fj.burns.2005.02.015","DOI":"10.1016\/j.burns.2005.02.015"},{"key":"ref=13","doi-asserted-by":"crossref","unstructured":"Reich-Schupke\u00a0S, Doerler\u00a0M, Wollina\u00a0U et al. Plattenepithelkarzinome in chronischen ven\u00f6sen Ulcera crurum. Daten aus dem deutschen Marjolin-Register und \u00dcbersichtsdarstellung. JDDG 2015; 13: 1006\u201314. Crossref: http:\/\/dx.doi.org\/10.1111%2Fddg.40_12649","DOI":"10.1111\/ddg.40_12649"},{"key":"ref=14","doi-asserted-by":"crossref","unstructured":"Sinha\u00a0S, Su\u00a0S, Workentine\u00a0M et al. Transcriptional analysis reveals evidence of chronically impeded ECM turnover and epithelium-to-mesenchyme transition in scar tissue giving rise to Marjolin's ulcer. J Burn Care Res 2017; 38: e14\u201322. PubMed: http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=27679957&dopt=Abstract, Crossref: http:\/\/dx.doi.org\/10.1097%2FBCR.0000000000000432","DOI":"10.1097\/BCR.0000000000000432"},{"key":"ref=15","unstructured":"Yu\u00a0N, Long\u00a0X, Lujan-Hernandez\u00a0JR et al. Marjolin's ulcer: a preventable malignancy arising from scars. World J Surg Oncol 2013; 11: 313. PubMed: http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=24341890&dopt=Abstract, Crossref: http:\/\/dx.doi.org\/10.1186%2F1477-7819-11-313"},{"key":"ref=16","doi-asserted-by":"crossref","unstructured":"Senet\u00a0P, Combemale\u00a0P, Debure\u00a0C et al. Malignancy and chronic leg ulcers: the value of systematic wound biopsies: a prospective, multicenter, cross-sectional study. Arch Dermatol 2012; 148: 704\u20138. PubMed: http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=22772403&dopt=Abstract, Crossref: http:\/\/dx.doi.org\/10.1001%2Farchdermatol.2011.3362","DOI":"10.1001\/archdermatol.2011.3362"},{"key":"ref=17","unstructured":"Ames\u00a0FC, Hickey\u00a0RC. Squamous cell carcinoma of the skin of the extremities. Int Adv Surg Oncol 1980; 3: 179\u201399. PubMed: http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=6926740&dopt=Abstract"},{"key":"ref=18","doi-asserted-by":"crossref","unstructured":"Baldursson\u00a0B, Sigurgeirsson\u00a0B, Lindel\u00f6f\u00a0B. Venous leg ulcers and squamous cell carcinoma: a large-scale epidemiological study. Br J Dermatol 1995; 133: 571\u20134. PubMed: http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=7577586&dopt=Abstract, Crossref: http:\/\/dx.doi.org\/10.1111%2Fj.1365-2133.1995.tb02707.x","DOI":"10.1111\/j.1365-2133.1995.tb02707.x"},{"key":"ref=19","doi-asserted-by":"crossref","unstructured":"Ogawa\u00a0B, Chen\u00a0M, Margolis\u00a0J et al. Marjolin's ulcer arising at the elbow: a case report and literature review. Hand (N Y) 2006; 1: 89\u201393. PubMed: http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=18780031&dopt=Abstract, Crossref: http:\/\/dx.doi.org\/10.1007%2Fs11552-006-9007-1","DOI":"10.1007\/s11552-006-9007-1"},{"key":"ref=20","doi-asserted-by":"crossref","unstructured":"Chiang\u00a0KH, Chou\u00a0AS, Hsu\u00a0YH et al. Marjolin's ulcer: MR appearance. AJR Am J Roentgenol 2006; 186: 819\u201320. PubMed: http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16498113&dopt=Abstract, Crossref: http:\/\/dx.doi.org\/10.2214%2FAJR.04.1921","DOI":"10.2214\/AJR.04.1921"},{"key":"ref=21","unstructured":"NCCN Guidelines for patients. Squamous cell skin cancer. (Version 2. Plymouth Meeting, PA: The National Comprehensive Cancer Network, 2020. https:\/\/www.nccn.org\/patients\/guidelines\/content\/PDF\/squamous_cell-patient.pdf Lest 23.2.2021."},{"key":"ref=22","doi-asserted-by":"crossref","unstructured":"Schell\u00a0AE, Russell\u00a0MA, Park\u00a0SS. Suggested excisional margins for cutaneous malignant lesions based on Mohs micrographic surgery. JAMA Facial Plast Surg 2013; 15: 337\u201343. PubMed: http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=23744451&dopt=Abstract, Crossref: http:\/\/dx.doi.org\/10.1001%2Fjamafacial.2013.1011","DOI":"10.1001\/jamafacial.2013.1011"},{"key":"ref=23","unstructured":"Xiang\u00a0F, Song\u00a0HP, Huang\u00a0YS. Clinical features and treatment of 140 cases of Marjolin's ulcer at a major burn center in southwest China. Exp Ther Med 2019; 17: 3403\u201310. PubMed: http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=30988718&dopt=Abstract, Crossref: http:\/\/dx.doi.org\/10.3892%2Fetm.2019.7364"},{"key":"ref=24","doi-asserted-by":"crossref","unstructured":"Bauer\u00a0T, David\u00a0T, Rimareix\u00a0F et al. Ulc\u00e8re de Marjolin sur ost\u00e9ite chronique: diagnostic et r\u00e9sultats du traitement: 7 cas. Rev Chir Orthop Repar Appar Mot 2007; 93: 63\u201371. PubMed: http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17389826&dopt=Abstract, Crossref: http:\/\/dx.doi.org\/10.1016%2FS0035-1040(07)90205-6","DOI":"10.1016\/S0035-1040(07)90205-6"},{"key":"ref=25","doi-asserted-by":"crossref","unstructured":"Pekarek\u00a0B, Buck\u00a0S, Osher\u00a0L. A comprehensive review on Marjolin's ulcus: diagnosis and treatment. J Am Col Certif Wound Spec 2011; 3: 60\u20134. PubMed: http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=24525526&dopt=Abstract, Crossref: http:\/\/dx.doi.org\/10.1016%2Fj.jcws.2012.04.001","DOI":"10.1016\/j.jcws.2012.04.001"}],"container-title":["Tidsskrift for Den norske legeforening"],"original-title":[],"language":"no","deposited":{"date-parts":[[2026,6,17]],"date-time":"2026-06-17T08:11:08Z","timestamp":1781683868000},"score":1,"resource":{"primary":{"URL":"https:\/\/tidsskriftet.no\/2021\/06\/noe-laere-av\/en-mann-i-40-arene-med-rask-forverring-av-kronisk-fotsar"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,6,28]]},"references-count":25,"journal-issue":{"issue":"10","published-online":{"date-parts":[[2021,6,29]]}},"URL":"https:\/\/doi.org\/10.4045\/tidsskr.20.0730","relation":{},"ISSN":["0029-2001","0807-7096"],"issn-type":[{"value":"0029-2001","type":"print"},{"value":"0807-7096","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,6,28]]}}}