{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,17]],"date-time":"2026-06-17T17:53:42Z","timestamp":1781718822434,"version":"3.54.5"},"reference-count":24,"publisher":"Norwegian Medical Association","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Tidsskr Nor Legeforen","Tidsskriftet"],"DOI":"10.4045\/tidsskr.25.0404","type":"journal-article","created":{"date-parts":[[2026,3,12]],"date-time":"2026-03-12T10:45:19Z","timestamp":1773312319000},"source":"Crossref","is-referenced-by-count":0,"title":["En kvinne i 60-\u00e5rene med alvorlig trombocytopeni etter elektiv kirurgi"],"prefix":"10.4045","volume":"146","author":[{"ORCID":"https:\/\/orcid.org\/0009-0001-0569-2929","authenticated-orcid":false,"given":"Morten Yung","family":"Isaksen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Siw Leiknes","family":"Ernstsen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5439-8411","authenticated-orcid":false,"given":"H\u00e5kon","family":"Reikvam","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6379-4018","authenticated-orcid":false,"given":"Ingvild J.","family":"L\u00e6greid","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elin Opheim","family":"Netland","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nessar Ahmad","family":"Azrakhsh","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria Therese","family":"Ahlen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Svein Tore","family":"Baksaas","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Torgeir","family":"Folkestad","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ingvild H.","family":"S\u00f8rvoll","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2479","published-online":{"date-parts":[[2026,3,12]]},"reference":[{"key":"ref=1","doi-asserted-by":"crossref","unstructured":"Bruserud\u00a0\u00d8, Mosevoll\u00a0KA, Kristoffersen\u00a0E et al. Trombocytopeni hos kritisk syke pasienter. Tidsskr Nor Legeforen 2021; 141. doi: 10.4045\/tidsskr.20.0458. PubMed: http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=33433088&dopt=Abstract, Crossref: http:\/\/dx.doi.org\/10.4045%2Ftidsskr.20.0458","DOI":"10.4045\/tidsskr.20.0458"},{"key":"ref=2","doi-asserted-by":"crossref","unstructured":"Skeith\u00a0L, Baumann Kreuziger\u00a0L, Crowther\u00a0MA et al. A practical approach to evaluating postoperative thrombocytopenia. Blood Adv 2020; 4: 776\u201383. PubMed: http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=32097460&dopt=Abstract, Crossref: http:\/\/dx.doi.org\/10.1182%2Fbloodadvances.2019001414","DOI":"10.1182\/bloodadvances.2019001414"},{"key":"ref=3","unstructured":"Universitetssykehuset Nord-Norge. Nasjonal behandlingstjeneste for avansert trombocyttimmunologi. https:\/\/www.unn.no\/fag-og-forskning\/nasjonal-behandlingstjeneste-for-avansert-trombocyttimmunologi\/ Lest 25.5.2025."},{"key":"ref=4","doi-asserted-by":"crossref","unstructured":"Shulman\u00a0NR, Aster\u00a0RH, Leitner\u00a0A et al. Immunoreactions involving platelets. V. Post-transfusion purpura due to a complement-fixing antibody against a genetically controlled platelet antigen. A proposed mechanism for thrombocytopenia and its relevance in \"autoimmunity\". J Clin Invest 1961; 40: 1597\u2013620. PubMed: http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16695867&dopt=Abstract, Crossref: http:\/\/dx.doi.org\/10.1172%2FJCI104383","DOI":"10.1172\/JCI104383"},{"key":"ref=5","doi-asserted-by":"crossref","unstructured":"Lynce\u00a0F, Yin\u00a0F, Alcorn\u00a0K et al. Post-transfusion purpura in an African-American man due to human platelet antigen-5b alloantibody: a case report. J Med Case Rep 2012; 6: 420. PubMed: http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=23234542&dopt=Abstract, Crossref: http:\/\/dx.doi.org\/10.1186%2F1752-1947-6-420","DOI":"10.1186\/1752-1947-6-420"},{"key":"ref=6","doi-asserted-by":"crossref","unstructured":"Vu\u00a0K, Leavitt\u00a0AD. Posttransfusion purpura with antibodies against human platelet antigen-4a following checkpoint inhibitor therapy: a case report and review of the literature. Transfusion 2018; 58: 2265\u20139. PubMed: http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=30222869&dopt=Abstract, Crossref: http:\/\/dx.doi.org\/10.1111%2Ftrf.14824","DOI":"10.1111\/trf.14824"},{"key":"ref=7","doi-asserted-by":"crossref","unstructured":"Taaning\u00a0E, Svejgaard\u00a0A. Post-transfusion purpura: a survey of 12 Danish cases with special reference to immunoglobulin G subclasses of the platelet antibodies. Transfus Med 1994; 4: 1\u20138. PubMed: http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=8012488&dopt=Abstract, Crossref: http:\/\/dx.doi.org\/10.1111%2Fj.1365-3148.1994.tb00236.x","DOI":"10.1111\/j.1365-3148.1994.tb00236.x"},{"key":"ref=8","doi-asserted-by":"crossref","unstructured":"Lucas\u00a0GF, Pittman\u00a0SJ, Davies\u00a0S et al. Post-transfusion purpura (PTP) associated with anti-HPA-1a, anti-HPA-2b and anti-HPA-3a antibodies. Transfus Med 1997; 7: 295\u20139. PubMed: http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=9510928&dopt=Abstract, Crossref: http:\/\/dx.doi.org\/10.1046%2Fj.1365-3148.1997.d01-39.x","DOI":"10.1046\/j.1365-3148.1997.d01-39.x"},{"key":"ref=9","doi-asserted-by":"crossref","unstructured":"Hawkins\u00a0J, Aster\u00a0RH, Curtis\u00a0BR. Post-Transfusion Purpura: Current Perspectives. J Blood Med 2019; 10: 405\u201315. PubMed: http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=31849555&dopt=Abstract, Crossref: http:\/\/dx.doi.org\/10.2147%2FJBM.S189176","DOI":"10.2147\/JBM.S189176"},{"key":"ref=10","doi-asserted-by":"crossref","unstructured":"Masson\u00a0E, Vidal\u00a0C, Deschamps\u00a0M et al. Incidence and risk factors of anti-HLA immunization after pregnancy. Hum Immunol 2013; 74: 946\u201351. PubMed: http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=23628391&dopt=Abstract, Crossref: http:\/\/dx.doi.org\/10.1016%2Fj.humimm.2013.04.025","DOI":"10.1016\/j.humimm.2013.04.025"},{"key":"ref=11","unstructured":"Direktoratet for medisinske produkter. Overv\u00e5king av blod - rapporter og artikler. \u00c5rsrapporter for transfusjonskomplikasjoner. https:\/\/www.dmp.no\/blod-celler-og-vev\/blodgivning-og-transfusjonsmedisin\/overvaking-av-blod---arsrapporter Lest 14.5.2025."},{"key":"ref=12","unstructured":"Bhamra\u00a0JS, Iversen\u00a0PO, Titze\u00a0TK et al. A Case of Posttransfusion Purpura with Severe Refractory Thrombocytopenia but No Cutaneous Manifestations. Case Rep Hematol 2018; 2018: 8187659. PubMed: http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=30510818&dopt=Abstract, Crossref: http:\/\/dx.doi.org\/10.1155%2F2018%2F8187659"},{"key":"ref=13","doi-asserted-by":"crossref","unstructured":"Politis\u00a0C, Wiersum-Osselton\u00a0J, Richardson\u00a0C et al. Adverse reactions following transfusion of blood components, with a focus on some rare reactions: Reports to the International Haemovigilance Network Database (ISTARE) in 2012-2016. Transfus Clin Biol 2022; 29: 243\u20139. PubMed: http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=35476961&dopt=Abstract, Crossref: http:\/\/dx.doi.org\/10.1016%2Fj.tracli.2022.03.005","DOI":"10.1016\/j.tracli.2022.03.005"},{"key":"ref=14","unstructured":"Shtalrid\u00a0M, Shvidel\u00a0L, Vorst\u00a0E et al. Post-transfusion purpura: a challenging diagnosis. Isr Med Assoc J 2006; 8: 672\u20134. PubMed: http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17125110&dopt=Abstract"},{"key":"ref=15","doi-asserted-by":"crossref","unstructured":"Lubenow\u00a0N, Eichler\u00a0P, Albrecht\u00a0D et al. Very low platelet counts in post-transfusion purpura falsely diagnosed as heparin-induced thrombocytopenia. Report of four cases and review of literature. Thromb Res 2000; 100: 115\u201325. PubMed: http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=11108897&dopt=Abstract, Crossref: http:\/\/dx.doi.org\/10.1016%2FS0049-3848(00)00311-X","DOI":"10.1016\/S0049-3848(00)00311-X"},{"key":"ref=16","doi-asserted-by":"crossref","unstructured":"Kroll\u00a0H, Kiefel\u00a0V, Mueller-Eckhardt\u00a0C. Post-transfusion purpura: clinical and immunologic studies in 38 patients. Infusionsther Transfusionsmed 1993; 20: 198\u2013204. PubMed: http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=8305860&dopt=Abstract","DOI":"10.1159\/000222844"},{"key":"ref=17","doi-asserted-by":"crossref","unstructured":"Mueller-Eckhardt\u00a0C, Lechner\u00a0K, Heinrich\u00a0D et al. Post-transfusion thrombocytopenic purpura: immunological and clinical studies in two cases and review of the literature. Blut 1980; 40: 249\u201357. PubMed: http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=7189423&dopt=Abstract, Crossref: http:\/\/dx.doi.org\/10.1007%2FBF01080184","DOI":"10.1007\/BF01080184"},{"key":"ref=18","doi-asserted-by":"crossref","unstructured":"Vogelsang\u00a0G, Kickler\u00a0TS, Bell\u00a0WR. Post-transfusion purpura: a report of five patients and a review of the pathogenesis and management. Am J Hematol 1986; 21: 259\u201367. PubMed: http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=3946408&dopt=Abstract, Crossref: http:\/\/dx.doi.org\/10.1002%2Fajh.2830210305","DOI":"10.1002\/ajh.2830210305"},{"key":"ref=19","doi-asserted-by":"crossref","unstructured":"Mueller-Eckhardt\u00a0C, Kiefel\u00a0V, Mueller-Eckhardt\u00a0G et al. Posttransfusion purpura. A survey of 13 cases. Klin Wochenschr 1986; 64: 1198\u2013203. PubMed: http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=3807265&dopt=Abstract, Crossref: http:\/\/dx.doi.org\/10.1007%2FBF01728461","DOI":"10.1007\/BF01728461"},{"key":"ref=20","doi-asserted-by":"crossref","unstructured":"Kickler\u00a0TS, Ness\u00a0PM, Herman\u00a0JH et al. Studies on the pathophysiology of posttransfusion purpura. Blood 1986; 68: 347\u201350. PubMed: http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=3524706&dopt=Abstract, Crossref: http:\/\/dx.doi.org\/10.1182%2Fblood.V68.2.347.347","DOI":"10.1182\/blood.V68.2.347.bloodjournal682347"},{"key":"ref=21","doi-asserted-by":"crossref","unstructured":"Menis\u00a0M, Forshee\u00a0RA, Anderson\u00a0SA et al. Posttransfusion purpura occurrence and potential risk factors among the inpatient US elderly, as recorded in large Medicare databases during 2011 through 2012. Transfusion 2015; 55: 284\u201395. PubMed: http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=25065878&dopt=Abstract, Crossref: http:\/\/dx.doi.org\/10.1111%2Ftrf.12782","DOI":"10.1111\/trf.12782"},{"key":"ref=22","doi-asserted-by":"crossref","unstructured":"Slichter\u00a0SJ. Post-transfusion purpura: response to steroids and association with red blood cell and lymphocytotoxic antibodies. Br J Haematol 1982; 50: 599\u2013605. PubMed: http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=7199931&dopt=Abstract, Crossref: http:\/\/dx.doi.org\/10.1111%2Fj.1365-2141.1982.tb01960.x","DOI":"10.1111\/j.1365-2141.1982.tb01960.x"},{"key":"ref=23","doi-asserted-by":"crossref","unstructured":"Mueller-Eckhardt\u00a0C, Kiefel\u00a0V. High-dose IgG for post-transfusion purpura-revisited. Blut 1988; 57: 163\u20137. PubMed: http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=3139110&dopt=Abstract, Crossref: http:\/\/dx.doi.org\/10.1007%2FBF00319544","DOI":"10.1007\/BF00319544"},{"key":"ref=24","doi-asserted-by":"crossref","unstructured":"Abramson\u00a0N, Eisenberg\u00a0PD, Aster\u00a0RH. Post-transfusion purpura: immunologic aspects and therapy. N Engl J Med 1974; 291: 1163\u20136. PubMed: http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=4472486&dopt=Abstract, Crossref: http:\/\/dx.doi.org\/10.1056%2FNEJM197411282912205","DOI":"10.1056\/NEJM197411282912205"}],"container-title":["Tidsskrift for Den norske legeforening"],"original-title":[],"language":"no","deposited":{"date-parts":[[2026,6,17]],"date-time":"2026-06-17T17:15:58Z","timestamp":1781716558000},"score":1,"resource":{"primary":{"URL":"https:\/\/tidsskriftet.no\/2026\/03\/noe-laere-av\/en-kvinne-i-60-arene-med-alvorlig-trombocytopeni-etter-elektiv-kirurgi"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3,12]]},"references-count":24,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2026,5,12]]}},"URL":"https:\/\/doi.org\/10.4045\/tidsskr.25.0404","relation":{},"ISSN":["0029-2001","0807-7096"],"issn-type":[{"value":"0029-2001","type":"print"},{"value":"0807-7096","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,3,12]]}}}