{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,8]],"date-time":"2026-06-08T20:20:11Z","timestamp":1780950011514,"version":"3.54.1"},"reference-count":20,"publisher":"The Korean Academy of Tuberculosis and Respiratory Diseases","issue":"4","license":[{"start":{"date-parts":[[2021,6,24]],"date-time":"2021-06-24T00:00:00Z","timestamp":1624492800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100003725","name":"National Research Foundation of Korea","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003725","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Ministry of Science and ICT","award":["2021M3E5D1A0201526521"],"award-info":[{"award-number":["2021M3E5D1A0201526521"]}]},{"name":"Ministry of Science and ICT","award":["2021R1C1C100950811"],"award-info":[{"award-number":["2021R1C1C100950811"]}]}],"content-domain":{"domain":["e-trd.org"],"crossmark-restriction":true},"short-container-title":["Tuberc Respir Dis"],"published-print":{"date-parts":[[2021,10,1]]},"abstract":"<jats:p>Background: Radial probe endobronchial ultrasound-guided transbronchial lung biopsy (RP-EBUS-TBLB) has improved the diagnostic yield of bronchoscopic biopsy of peripheral pulmonary lesions (PPLs). The diagnostic yield and complications of RP-EBUS-TBLB for PPLs vary depending on the technique, such as using a guide sheath (GS) or fluoroscopy. In this study, we investigated the utility of RP-EBUS-TBLB using a GS without fluoroscopy for diagnosing PPLs.Methods: We retrospectively reviewed data from 607 patients who underwent RP-EBUS of PPLs from January 2019 to July 2020. TBLB was performed using RP-EBUS with a GS without fluoroscopy. The diagnostic yield and complications were assessed. Multivariable logistic regression analyses were used to identify factors affecting the diagnostic yields.Results: The overall diagnostic accuracy was 76.1% (462\/607). In multivariable analyses, the size of the lesion (\u226520 mm; odds ratio [OR], 2.06; 95% confidence interval [CI], 1.27\u20133.33; p=0.003), positive bronchus sign in chest computed tomography (OR, 2.30; 95% CI, 1.40\u20133.78; p=0.001), a solid lesion (OR, 2.40; 95% CI, 1.31\u20134.41; p=0.005), and an EBUS image with the probe within the lesion (OR, 6.98; 95% CI, 4.38\u201311.12; p&lt;0.001) were associated with diagnostic success. Pneumothorax occurred in 2.0% (12\/607) of cases and chest tube insertion was required in 0.5% (3\/607) of patients.Conclusion: RP-EBUS-TBLB using a GS without fluoroscopy is a highly accurate diagnostic method in diagnosing PPLs that does not involve radiation exposure and has acceptable complication rates.<\/jats:p>","DOI":"10.4046\/trd.2021.0002","type":"journal-article","created":{"date-parts":[[2021,6,24]],"date-time":"2021-06-24T08:31:27Z","timestamp":1624523487000},"page":"282-290","update-policy":"https:\/\/doi.org\/10.4046\/crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["Radial Probe Endobronchial Ultrasound Using Guide Sheath-Guided Transbronchial Lung Biopsy in Peripheral Pulmonary Lesions without Fluoroscopy"],"prefix":"10.4046","volume":"84","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2931-6861","authenticated-orcid":true,"given":"Kyung 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Soo","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Min Hye","family":"Jang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7104-8325","authenticated-orcid":true,"given":"June Hong","family":"Ahn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2481","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.12701\/yujm.2020.00584"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1111\/resp.12980"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1016\/j.chest.2019.10.042"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.00075310"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1378\/chest.126.3.959"},{"key":"ref6","first-page":"1469","volume-title":"Radiation dose to patients and clinicians during fluoroscopically-guided biopsy 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diagnostic performances among bronchoscopic sampling techniques in the diagnosis of peripheral pulmonary lesions","author":"Boonsarngsuk","year":"2015"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1513\/annalsats.201311-384oc"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1159\/000431383"}],"container-title":["Tuberculosis and Respiratory Diseases"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/e-trd.org\/upload\/pdf\/trd-2021-0002.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/e-trd.org\/journal\/view.php?doi=10.4046\/trd.2021.0002","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/e-trd.org\/upload\/pdf\/trd-2021-0002.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,10,5]],"date-time":"2021-10-05T02:15:24Z","timestamp":1633400124000},"score":1,"resource":{"primary":{"URL":"http:\/\/e-trd.org\/journal\/view.php?doi=10.4046\/trd.2021.0002"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,10,1]]},"references-count":20,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2021,10]]}},"URL":"https:\/\/doi.org\/10.4046\/trd.2021.0002","relation":{},"ISSN":["1738-3536","2005-6184"],"issn-type":[{"value":"1738-3536","type":"print"},{"value":"2005-6184","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,10,1]]},"assertion":[{"value":"2021-01-02","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication 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