{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,19]],"date-time":"2026-09-19T02:16:06Z","timestamp":1789784166473,"version":"4.0.1"},"reference-count":128,"publisher":"Oxford University Press (OUP)","issue":"8","license":[{"start":{"date-parts":[[2025,1,6]],"date-time":"2025-01-06T00:00:00Z","timestamp":1736121600000},"content-version":"vor","delay-in-days":158,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,8,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Mother and child are immunologically interconnected by mechanisms that we are only beginning to understand. During pregnancy, multiple molecular and cellular factors of maternal origin are transferred across the placenta and influence the development and function of the fetal and newborn immune system. Altered maternal immune states arising from pregnancy-associated infections or immunizations have the potential to program offspring immune function in ways that may have long-term health consequences. In this study, we review current literature on the impact of prenatal infection and vaccination on the developing immune system, highlight knowledge gaps, and look to the horizon to envision maternal interventions that could benefit both the mother and her child.<\/jats:p>","DOI":"10.4049\/immunohorizons.2400032","type":"journal-article","created":{"date-parts":[[2024,8,22]],"date-time":"2024-08-22T12:40:07Z","timestamp":1724330407000},"page":"552-562","source":"Crossref","is-referenced-by-count":10,"title":["From Womb to World: Exploring the Immunological Connections between Mother and Child"],"prefix":"10.1093","volume":"8","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6602-3374","authenticated-orcid":false,"given":"Bobby J","family":"Cherayil","sequence":"first","affiliation":[{"name":"Mucosal Immunology and Biology Research Center, Mass General for Children , Charlestown, MA"},{"name":"Department of Pediatrics, Harvard Medical School , Boston, MA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nitya","family":"Jain","sequence":"additional","affiliation":[{"name":"Mucosal Immunology and Biology Research Center, Mass General for Children , Charlestown, MA"},{"name":"Department of Pediatrics, Harvard Medical School , Boston, MA"},{"name":"Center for Computational and Integrative Biology, Mass General Brigham , Boston, MA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2024,8,22]]},"reference":[{"key":"2025010608555254700_r1","doi-asserted-by":"crossref","first-page":"508","DOI":"10.1038\/nri.2017.58","article-title":"How nutrition and the maternal microbiota shape the neonatal immune system","volume":"17","author":"Macpherson","year":"2017","journal-title":"Nat. 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