{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T23:55:03Z","timestamp":1790294103270,"version":"4.1.0"},"reference-count":17,"publisher":"Wiley","license":[{"start":{"date-parts":[[2011,1,1]],"date-time":"2011-01-01T00:00:00Z","timestamp":1293840000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Thyroid Research"],"published-print":{"date-parts":[[2011]]},"abstract":"<jats:p><jats:italic>Background<\/jats:italic>. Vitiligo is a common skin disorder characterized by macular depigmentation of the skin. The etiopathogenesis of the disease is still unclear, but there is evidence that autoimmunity and endocrine disfunction may be involved.<jats:italic>Objective<\/jats:italic>. The aim of this study was to determine whether vitiligo is statistically associated with thyroid autoimmunity.<jats:italic>Method<\/jats:italic>. In a prospective case-control study, we compared the frequency of thyroid autoantibodies (thyroglobulin antibody, anti-Tg and thyroid peroxidase antibody, and anti-TPO) in 33 patients with vitiligo and in 33 healthy volunteers. Thyroid autoantibodies and thyroid hormones (thyroxine (T4), triiodothyronine (T3), and thyroid stimulating hormone (TSH) were measured in all subjects.<jats:italic>Results<\/jats:italic>. Thyroid functional abnormalities were found in 6 (18.18%) patients. Anti-Tg and anti-TPO were positive in 9 (27.27%) and 8 (24.24%) patients, respectively. In control group, only one subject (3.03%) had abnormalities in thyroid hormonal status, and two subjects had positive thyroid autoantibodies. Compared with the control group, the frequency of both anti-Tg and anti-TPO was significantly higher in those with vitiligo ().<jats:italic>Conclusion<\/jats:italic>. This study shows a significant association between vitiligo and thyroid autoimmunity, and that tests to detect thyroid autoantibodies are relevant in patients with vitiligo.<\/jats:p>","DOI":"10.4061\/2011\/938257","type":"journal-article","created":{"date-parts":[[2011,5,4]],"date-time":"2011-05-04T17:31:45Z","timestamp":1304530305000},"page":"1-3","source":"Crossref","is-referenced-by-count":18,"title":["Association between Vitiligo and Thyroid Autoimmunity"],"prefix":"10.4061","volume":"2011","author":[{"given":"Emina","family":"Kasumagic-Halilovic","sequence":"first","affiliation":[{"name":"Department of Dermatology and Venereology, Sarajevo University Clinical Center, Bolni\u010dka 25, 71 000 Sarajevo, Bosnia and Herzegovina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4227-6921","authenticated-orcid":true,"given":"Asja","family":"Prohic","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Venereology, Sarajevo University Clinical Center, Bolni\u010dka 25, 71 000 Sarajevo, Bosnia and Herzegovina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Begler","family":"Begovic","sequence":"additional","affiliation":[{"name":"Department of Clinical Pharmacology, Sarajevo University Clinical Center, Sarajevo, Bosnia and Herzegovina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nermina","family":"Ovcina-Kurtovic","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Venereology, Sarajevo University Clinical Center, Bolni\u010dka 25, 71 000 Sarajevo, Bosnia and Herzegovina"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","reference":[{"issue":"2","key":"1","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1016\/0738-081X(89)90063-1","volume":"7","year":"1989","journal-title":"Clinics in Dermatology"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1159\/000131485"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0749.2003.00023.x"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1097\/00000372-200404000-00004"},{"issue":"2","key":"5","doi-asserted-by":"crossref","first-page":"120","DOI":"10.2340\/0001555574124128","volume":"74","year":"1994","journal-title":"Acta Dermato-Venereologica"},{"issue":"8","key":"6","doi-asserted-by":"crossref","first-page":"628","DOI":"10.1007\/BF03343905","volume":"24","year":"2001","journal-title":"Journal of Endocrinological Investigation"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-4632.2007.03195.x"},{"issue":"1","key":"8","first-page":"12","volume":"17","year":"2008","journal-title":"Acta Dermatovenerologica Alpina"},{"key":"9","first-page":"317","volume":"84","year":"1941","journal-title":"Dermatologica"},{"issue":"2","key":"10","first-page":"128","volume":"38","year":"2006","journal-title":"Kuwait Medical Journal"},{"issue":"1","key":"11","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1111\/j.1365-4362.1996.tb01609.x","volume":"35","year":"1996","journal-title":"International Journal of Dermatology"},{"key":"12","doi-asserted-by":"publisher","DOI":"10.4103\/0019-5154.39733"},{"key":"13","doi-asserted-by":"publisher","DOI":"10.1186\/1471-5945-6-3"},{"key":"14","first-page":"68","volume":"48","year":"2003","journal-title":"Indian Journal of Dermatology"},{"key":"15","doi-asserted-by":"publisher","DOI":"10.1080\/08916930410001710857"},{"key":"16","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.153.7.862"},{"issue":"2","key":"17","first-page":"89","volume":"3","year":"1991","journal-title":"Thyroidology"}],"container-title":["Journal of Thyroid Research"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/jtr\/2011\/938257.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/jtr\/2011\/938257.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/jtr\/2011\/938257.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,4,6]],"date-time":"2024-04-06T14:22:02Z","timestamp":1712413322000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.hindawi.com\/journals\/jtr\/2011\/938257\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011]]},"references-count":17,"alternative-id":["938257","938257"],"URL":"https:\/\/doi.org\/10.4061\/2011\/938257","relation":{},"ISSN":["2042-0072"],"issn-type":[{"value":"2042-0072","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011]]}}}