{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T10:30:41Z","timestamp":1722508241724},"reference-count":14,"publisher":"Hindawi Limited","license":[{"start":{"date-parts":[[2010,7,27]],"date-time":"2010-07-27T00:00:00Z","timestamp":1280188800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pathology Research International"],"published-print":{"date-parts":[[2010,7,27]]},"abstract":"<jats:p>Unexpected child death investigation is a difficult area of forensic practice in view of the wide range of possible genetic, congenital, and acquired natural and nonnatural causes. Idiopathic infantile arterial calcification (IIAC) is a rare autosomic recessive disease usually diagnosed postmortem. Inactivating mutations of the ENPP1 gene were described in 80% of the cases with IIAC. We report a case of a 5-year-old girl submitted to a forensic autopsy due to sudden death and possible medical negligence\/parents child abuse. Major alterations found (intimal proliferation and deposition of calcium hydroxyapatite around the internal elastic lamina and media of arteries; acute myocardial infarct, stenotic and calcified coronary artery; perivascular and interstitial myocardial fibrosis; and subendocardial fibroelastosis) were diagnostic of IIAC. We reviewed IIAC cases published in the English literature and highlight the importance of adequate autopsy evaluation in cases of sudden child death.<\/jats:p>","DOI":"10.4061\/2010\/185314","type":"journal-article","created":{"date-parts":[[2010,7,27]],"date-time":"2010-07-27T14:37:41Z","timestamp":1280241461000},"page":"1-5","source":"Crossref","is-referenced-by-count":7,"title":["Idiopathic Infantile Arterial Calcification: A Rare Cause of Sudden Unexpected Death in Childhood"],"prefix":"10.1155","volume":"2010","author":[{"given":"Susana","family":"Guimar\u00e3es","sequence":"first","affiliation":[{"name":"Institute of Molecular Pathology and  Immunology, University of Porto (IPATIMUP), Porto, Portugal"},{"name":"Department of Pathology, Hospital de S\u00e3o Jo\u00e3o, Porto, Portugal"}]},{"given":"Jos\u00e9 Manuel","family":"Lopes","sequence":"additional","affiliation":[{"name":"Institute of Molecular Pathology and  Immunology, University of Porto (IPATIMUP), Porto, Portugal"},{"name":"Department of Pathology, Hospital de S\u00e3o Jo\u00e3o, Porto, Portugal"},{"name":"Medical Faculty, University of Porto, Porto, Portugal"}]},{"given":"Jos\u00e9 Bessa","family":"Oliveira","sequence":"additional","affiliation":[{"name":"Legal Medicine Institute, North Delegation, Porto, Portugal"},{"name":"Abel Salazar Institute of Medical Sciences (ICBAS), University of Porto, Porto, Portugal"}]},{"given":"Agostinho","family":"Santos","sequence":"additional","affiliation":[{"name":"Medical Faculty, University of Porto, Porto, Portugal"},{"name":"Legal Medicine Institute, North Delegation, Porto, Portugal"}]}],"member":"98","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-3046.2005.00414.x"},{"issue":"3","key":"8","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1016\/0002-8703(94)90683-1","volume":"127","year":"1994","journal-title":"American Heart Journal"},{"issue":"10","key":"9","doi-asserted-by":"crossref","first-page":"1265","DOI":"10.1111\/j.1651-2227.2000.tb00747.x","volume":"89","year":"2000","journal-title":"Acta Paediatrica"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.1007\/s10024-001-0256-2"},{"issue":"8","key":"11","first-page":"652","volume":"34","year":"2004","journal-title":"Pediatric Radiology"},{"key":"12","doi-asserted-by":"publisher","DOI":"10.1007\/s00431-006-0146-8"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cdip.2006.03.008"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1007\/s10024-005-1155-8"},{"issue":"4","key":"4","doi-asserted-by":"crossref","first-page":"426","DOI":"10.1136\/heart.88.4.426","volume":"88","year":"2002","journal-title":"Heart"},{"key":"5","first-page":"17","volume":"55","year":"1901","journal-title":"Guys.Hospital Reports"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1002\/uog.7438"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.a.30800"},{"key":"13","doi-asserted-by":"publisher","DOI":"10.1007\/s00774-005-0645-0"},{"key":"14","doi-asserted-by":"publisher","DOI":"10.1017\/S1047951108003168"}],"container-title":["Pathology Research International"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/archive\/2010\/185314.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/archive\/2010\/185314.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/archive\/2010\/185314.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,12,9]],"date-time":"2020-12-09T03:54:55Z","timestamp":1607486095000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.hindawi.com\/journals\/pri\/2010\/185314\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,7,27]]},"references-count":14,"alternative-id":["185314","185314"],"URL":"https:\/\/doi.org\/10.4061\/2010\/185314","relation":{},"ISSN":["2042-003X"],"issn-type":[{"value":"2042-003X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,7,27]]}}}