{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T02:32:45Z","timestamp":1790389965404,"version":"4.1.0"},"reference-count":44,"publisher":"The Korean Society of Applied Pharmacology","issue":"3","license":[{"start":{"date-parts":[[2021,5,1]],"date-time":"2021-05-01T00:00:00Z","timestamp":1619827200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"name":"Administration of International Cooperation and Knowledge Exchange (ICKEA), King Faisal University","award":["Project No. IC-01-20"],"award-info":[{"award-number":["Project No. IC-01-20"]}]},{"DOI":"10.13039\/501100001691","name":"Japanese Society for the Promotion of Science","doi-asserted-by":"crossref","award":["16H06575"],"award-info":[{"award-number":["16H06575"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100001691","name":"Japanese Society for the Promotion of Science","doi-asserted-by":"crossref","award":["20K07610"],"award-info":[{"award-number":["20K07610"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Japan Initiative for Global Research Network on Infectious Diseases","award":["JP20wm0125002"],"award-info":[{"award-number":["JP20wm0125002"]}]}],"content-domain":{"domain":["www.biomolther.org"],"crossmark-restriction":true},"short-container-title":["Biomol Ther (Seoul)"],"published-print":{"date-parts":[[2021,5,1]]},"DOI":"10.4062\/biomolther.2020.201","type":"journal-article","created":{"date-parts":[[2021,1,11]],"date-time":"2021-01-11T04:58:19Z","timestamp":1610341099000},"page":"282-289","update-policy":"https:\/\/doi.org\/10.4062\/crossmark_policy","source":"Crossref","is-referenced-by-count":36,"title":["Discovery of New Fusion Inhibitor Peptides against SARS-CoV-2 by Targeting the Spike S2 Subunit"],"prefix":"10.4062","volume":"29","author":[{"given":"Mahmoud","family":"Kandeel","sequence":"first","affiliation":[{"name":"Department of Biomedical Sciences, College of Veterinary Medicine, King Faisal University, Al-Ahsa 31982, Saudi Arabia"},{"name":"Department of Pharmacology, Faculty of Veterinary Medicine, Kafrelsheikh University, Kafrelsheikh 33516, Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mizuki","family":"Yamamoto","sequence":"additional","affiliation":[{"name":"Research Center for Asian Infectious Diseases, Institute of Medical Science, The University of Tokyo, Tokyo 108-8639, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hideki","family":"Tani","sequence":"additional","affiliation":[{"name":"Department of Virology, Toyama Institute of Health, Toyama 939-0363, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ayako","family":"Kobayashi","sequence":"additional","affiliation":[{"name":"Research Center for Asian Infectious Diseases, Institute of Medical Science, The University of Tokyo, Tokyo 108-8639, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jin","family":"Gohda","sequence":"additional","affiliation":[{"name":"Research Center for Asian Infectious Diseases, Institute of Medical Science, The University of Tokyo, Tokyo 108-8639, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasushi","family":"Kawaguchi","sequence":"additional","affiliation":[{"name":"Research Center for Asian Infectious Diseases, Institute of Medical Science, The University of Tokyo, Tokyo 108-8639, Japan"},{"name":"Division of Molecular Virology, Department of Microbiology and Immunology, The Institute of Medical Science, The University of Tokyo, Tokyo 108-8639, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Byoung Kwon","family":"Park","sequence":"additional","affiliation":[{"name":"Department of Microbiology, Hallym University College of Medicine, Chuncheon 24252, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hyung-Joo","family":"Kwon","sequence":"additional","affiliation":[{"name":"Department of Microbiology, Hallym University College of Medicine, Chuncheon 24252, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun-ichiro","family":"Inoue","sequence":"additional","affiliation":[{"name":"Senior Professor Office, The University of Tokyo, Tokyo 108-8639, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdallah","family":"Alkattan","sequence":"additional","affiliation":[{"name":"Department of Biomedical Sciences, College of Veterinary Medicine, King Faisal University, Al-Ahsa 31982, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2506","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1007\/s40005-016-0253-0"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.77.16.8801-8811.2003"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pcbi.1004494"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejmech.2016.05.027"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1002\/jcb.21790"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1155\/2014\/825039"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkt450"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.02433-13"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1711837115"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1099\/jgv.0.000991"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2020.02.052"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.00827-09"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.01815-18"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1038\/s41563-018-0194-2"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1126\/science.aan0516"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1080\/07391102.2020.1784291"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1016\/j.lfs.2020.117627"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1016\/j.compbiolchem.2018.05.020"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.4062\/biomolther.2019.202"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1038\/nature17200"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1016\/j.antiviral.2008.10.001"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(04)15788-7"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms4067"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.1016\/j.vetmic.2008.10.009"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2006.12.022"},{"key":"ref26","doi-asserted-by":"publisher","DOI":"10.1093\/ije\/dyaa033"},{"key":"ref27","doi-asserted-by":"publisher","DOI":"10.1002\/jmv.20095"},{"key":"ref28","doi-asserted-by":"publisher","DOI":"10.1016\/j.virusres.2006.03.001"},{"key":"ref29","doi-asserted-by":"publisher","DOI":"10.1002\/jcp.30032"},{"key":"ref30","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jctc.8b01123"},{"key":"ref31","doi-asserted-by":"publisher","DOI":"10.1016\/j.ultrasmedbio.2018.10.003"},{"key":"ref32","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1007236"},{"key":"ref33","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0139652"},{"key":"ref34","doi-asserted-by":"publisher","DOI":"10.1038\/s41591-020-0868-6"},{"key":"ref35","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.02499-09"},{"key":"ref36","doi-asserted-by":"publisher","DOI":"10.1002\/jcc.20291"},{"key":"ref37","doi-asserted-by":"crossref","unstructured":"Vhora, I., Patil, S., Bhatt, P. and Misra, A. (2015) Chapter one - proteinand peptide-drug conjugates: an emerging drug delivery technology. In: Advances in Protein Chemistry and Structural Biology (R. Donev, Ed.), pp. 1-55. Academic Press.","DOI":"10.1016\/bs.apcsb.2014.11.001"},{"key":"ref38","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0096790"},{"key":"ref39","doi-asserted-by":"publisher","DOI":"10.1016\/j.virusres.2014.10.007"},{"key":"ref40","doi-asserted-by":"publisher","DOI":"10.1126\/sciadv.aav4580"},{"key":"ref41","doi-asserted-by":"publisher","DOI":"10.3390\/v12060629"},{"key":"ref42","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M111.317883"},{"key":"ref43","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.00635-20"},{"key":"ref44","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2020.04.035"}],"container-title":["Biomolecules &amp; Therapeutics"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/pdf.medrang.co.kr\/BT2\/2021\/029\/BT2029-03-282.pdf","content-type":"unspecified","content-version":"tdm","intended-application":"text-mining"},{"URL":"http:\/\/pdf.medrang.co.kr\/BT2\/2021\/029\/BT2029-03-282.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,4,29]],"date-time":"2021-04-29T06:38:55Z","timestamp":1619678335000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.biomolther.org\/journal\/view.html?doi=10.4062\/biomolther.2020.201"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,5,1]]},"references-count":44,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2021,5,1]]}},"alternative-id":["10.4062\/biomolther.2020.201"],"URL":"https:\/\/doi.org\/10.4062\/biomolther.2020.201","relation":{},"ISSN":["1976-9148","2005-4483"],"issn-type":[{"value":"1976-9148","type":"print"},{"value":"2005-4483","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,5,1]]},"assertion":[{"value":"http:\/\/www.biomolther.org\/journal\/view.html?doi=10.4062\/biomolther.2020.201","URL":"http:\/\/www.biomolther.org\/journal\/view.html?doi=10.4062\/biomolther.2020.201","name":"the_journal","label":"Biomolecules & Therapeutics","group":{"name":"multiple_resolution","label":"Full text available at:"}},{"value":"2020-11-06","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-12-08","order":1,"name":"revised","label":"Revised","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-12-10","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-01-11","order":3,"name":"published","label":"Online First","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-05-01","order":4,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}},{"value":"\u00a9 2021 The Korean Society of Applied Pharmacology","name":"copyright","label":"Copyright","group":{"name":"Copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.","name":"license","label":"License","explanation":{"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},"group":{"name":"Copyright_and_licensing","label":"Copyright and Licensing"}}]}}