{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T12:54:41Z","timestamp":1782996881408,"version":"3.54.5"},"reference-count":76,"publisher":"The Korean Society of Applied Pharmacology","issue":"6","license":[{"start":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T00:00:00Z","timestamp":1761523200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100002475","name":"Duksung Women\u2019s University","doi-asserted-by":"crossref","award":["2023-3000009004"],"award-info":[{"award-number":["2023-3000009004"]}],"id":[{"id":"10.13039\/501100002475","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["www.biomolther.org"],"crossmark-restriction":true},"short-container-title":["Biomol Ther (Seoul)"],"published-print":{"date-parts":[[2025,11,1]]},"DOI":"10.4062\/biomolther.2025.153","type":"journal-article","created":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T01:53:42Z","timestamp":1761530022000},"page":"907-923","update-policy":"https:\/\/doi.org\/10.4062\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["CAR-Based Cell and Gene Therapies: Global Clinical Landscape and Emerging Therapeutic Strategies from ClinicalTrials.gov"],"prefix":"10.4062","volume":"33","author":[{"given":"Saerom","family":"Moon","sequence":"first","affiliation":[{"name":"College of Pharmacy, Duksung Women\u2019s University, Seoul 01369, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kyoung","family":"Song","sequence":"additional","affiliation":[{"name":"College of Pharmacy, Duksung Women\u2019s University, Seoul 01369, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2506","published-online":{"date-parts":[[2025,10,27]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1007\/s11864-020-0706-6"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1038\/ni929"},{"key":"ref3","unstructured":"BLOOMBERG (2019) Bristol-Myers Squibb buying Celgene in <span>$<\/span>74 billion deal. In In St. Louis Post-Dispatch, B4."},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2025.1583116"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.4062\/biomolther.2022.015"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph191912366"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1038\/s41590-023-01659-y"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1158\/2159-8290.CD-20-0556"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcyt.2014.03.009"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2025.1603757"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1186\/s13045-024-01616-8"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1186\/s13045-017-0519-7"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1038\/s41409-020-0956-8"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1097\/BS9.0000000000000118"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V128.22.5702.5702"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.3390\/ijms241411803"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.3390\/ijms251910365"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1186\/s12935-023-02923-9"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.3390\/biom12091303"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1016\/S2352-3026(22)00291-5"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2004-12-4797"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.3389\/fmed.2018.00150"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1111\/imr.12139"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.1186\/s40164-025-00633-8"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.1111\/ejh.13170"},{"key":"ref26","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0804788105"},{"key":"ref27","doi-asserted-by":"publisher","DOI":"10.1038\/35642"},{"key":"ref28","doi-asserted-by":"publisher","DOI":"10.7150\/ijbs.88539"},{"key":"ref29","doi-asserted-by":"publisher","DOI":"10.1016\/j.ymthe.2024.04.005"},{"key":"ref30","doi-asserted-by":"publisher","DOI":"10.1016\/j.stem.2018.06.002"},{"key":"ref31","doi-asserted-by":"publisher","DOI":"10.1016\/j.healthpol.2024.105153"},{"key":"ref32","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1910607"},{"key":"ref33","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(18)30864-7"},{"key":"ref34","doi-asserted-by":"publisher","DOI":"10.1001\/jamanetworkopen.2020.2072"},{"key":"ref35","doi-asserted-by":"publisher","DOI":"10.1038\/s41591-019-0564-6"},{"key":"ref36","doi-asserted-by":"publisher","DOI":"10.1186\/s12935-024-03479-y"},{"key":"ref37","doi-asserted-by":"publisher","DOI":"10.1038\/nrd.2016.80"},{"key":"ref38","doi-asserted-by":"publisher","DOI":"10.1186\/s13287-021-02462-y"},{"key":"ref39","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1407222"},{"key":"ref40","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1709866"},{"key":"ref41","doi-asserted-by":"publisher","DOI":"10.3390\/cancers12071915"},{"key":"ref42","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2023.1188049"},{"key":"ref43","doi-asserted-by":"publisher","DOI":"10.1038\/s41577-021-00547-6"},{"key":"ref44","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2025.1615760"},{"key":"ref45","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2014.15939"},{"key":"ref46","doi-asserted-by":"publisher","DOI":"10.1021\/cen-09535-notw12"},{"key":"ref47","doi-asserted-by":"publisher","DOI":"10.1038\/s12276-023-01068-z"},{"key":"ref48","doi-asserted-by":"publisher","DOI":"10.1016\/S0198-8859(99)00170-6"},{"key":"ref49","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1910160117"},{"key":"ref50","doi-asserted-by":"publisher","DOI":"10.1186\/s13046-022-02327-z"},{"key":"ref51","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2017.01124"},{"key":"ref52","doi-asserted-by":"publisher","DOI":"10.1038\/s41423-024-01207-0"},{"key":"ref53","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-019-13368-y"},{"key":"ref54","doi-asserted-by":"publisher","DOI":"10.1159\/000524392"},{"key":"ref55","doi-asserted-by":"publisher","DOI":"10.1038\/s41571-019-0297-y"},{"key":"ref56","doi-asserted-by":"publisher","DOI":"10.1016\/j.ymthe.2017.06.012"},{"key":"ref57","doi-asserted-by":"publisher","DOI":"10.1111\/cts.12586"},{"key":"ref58","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1804980"},{"key":"ref59","doi-asserted-by":"publisher","DOI":"10.1111\/j.1752-8062.2011.00275.x"},{"key":"ref60","doi-asserted-by":"publisher","DOI":"10.1038\/s41409-020-01134-4"},{"key":"ref61","doi-asserted-by":"publisher","DOI":"10.3390\/cells12121606"},{"key":"ref62","doi-asserted-by":"publisher","DOI":"10.1016\/S0161-5890(00)00076-6"},{"key":"ref63","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.1400330"},{"key":"ref64","doi-asserted-by":"publisher","DOI":"10.61173\/db2q9t74"},{"key":"ref65","doi-asserted-by":"publisher","DOI":"10.1038\/s41423-020-00555-x"},{"key":"ref66","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2022.1035276"},{"key":"ref67","doi-asserted-by":"publisher","DOI":"10.1016\/j.phrs.2020.104889"},{"key":"ref68","doi-asserted-by":"publisher","DOI":"10.1016\/j.omto.2022.10.011"},{"key":"ref69","doi-asserted-by":"publisher","DOI":"10.1186\/s13045-019-0732-7"},{"key":"ref70","unstructured":"Yang, J., Hu, S., Shangguan, J., Eresen, A., Li, Y., Pan, L., Ma, Q., Velichko, Y., Wang, J., Hu, C., Yaghmai, V. and Zhang, Z. (2019) Dendritic cell immunotherapy induces anti-tumor effect in a transgenic mouse model of pancreatic ductal adenocarcinoma. <i>Am. J. Cancer Res.<\/i> <b>9<\/b>, 2456-2468."},{"key":"ref71","doi-asserted-by":"publisher","DOI":"10.1186\/s13045-022-01354-9"},{"key":"ref72","doi-asserted-by":"publisher","DOI":"10.1186\/s40364-022-00364-6"},{"key":"ref73","doi-asserted-by":"publisher","DOI":"10.1186\/s13045-023-01492-8"},{"key":"ref74","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2022.927153"},{"key":"ref75","doi-asserted-by":"publisher","DOI":"10.1038\/s41420-024-02077-1"},{"key":"ref76","doi-asserted-by":"publisher","DOI":"10.1186\/s12943-024-02151-3"}],"container-title":["Biomolecules &amp; Therapeutics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pdf.medrang.co.kr\/BT2\/2025\/033\/BT033-06-907.pdf","content-type":"unspecified","content-version":"tdm","intended-application":"text-mining"},{"URL":"https:\/\/pdf.medrang.co.kr\/BT2\/2025\/033\/BT033-06-907.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,10]],"date-time":"2025-11-10T05:28:53Z","timestamp":1762752533000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.biomolther.org\/journal\/view.html?doi=10.4062\/biomolther.2025.153"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,10,27]]},"references-count":76,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2025,11,1]]}},"alternative-id":["10.4062\/biomolther.2025.153"],"URL":"https:\/\/doi.org\/10.4062\/biomolther.2025.153","relation":{},"ISSN":["1976-9148","2005-4483"],"issn-type":[{"value":"1976-9148","type":"print"},{"value":"2005-4483","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,10,27]]},"assertion":[{"value":"http:\/\/www.biomolther.org\/journal\/view.html?doi=10.4062\/biomolther.2025.153","URL":"http:\/\/www.biomolther.org\/journal\/view.html?doi=10.4062\/biomolther.2025.153","name":"the_journal","label":"Biomolecules & Therapeutics","group":{"name":"multiple_resolution","label":"Full text available at:"}},{"value":"2025-08-12","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-09-19","order":1,"name":"revised","label":"Revised","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-09-30","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-10-27","order":3,"name":"published","label":"Online First","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-11-01","order":4,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}},{"value":"\u00a9 2025 The Korean Society of Applied Pharmacology","name":"copyright","label":"Copyright","group":{"name":"Copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.","name":"license","label":"License","explanation":{"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},"group":{"name":"Copyright_and_licensing","label":"Copyright and Licensing"}}]}}