{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,14]],"date-time":"2026-05-14T06:18:51Z","timestamp":1778739531644,"version":"3.51.4"},"reference-count":32,"publisher":"The Korean Society of Applied Pharmacology","issue":"3","license":[{"start":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T00:00:00Z","timestamp":1777507200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100003725","name":"National Research Foundation of Korea","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003725","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100014188","name":"Korean government","doi-asserted-by":"publisher","award":["NRF-2020R1A5A2019210"],"award-info":[{"award-number":["NRF-2020R1A5A2019210"]}],"id":[{"id":"10.13039\/501100014188","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100014188","name":"Korean government","doi-asserted-by":"publisher","award":["NRF- 2022R1I1A1A01062818"],"award-info":[{"award-number":["NRF- 2022R1I1A1A01062818"]}],"id":[{"id":"10.13039\/501100014188","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002701","name":"Ministry of Education","doi-asserted-by":"publisher","award":["RS-2023-00270936"],"award-info":[{"award-number":["RS-2023-00270936"]}],"id":[{"id":"10.13039\/501100002701","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["www.biomolther.org"],"crossmark-restriction":true},"short-container-title":["Biomol Ther (Seoul)"],"published-print":{"date-parts":[[2026,5,1]]},"DOI":"10.4062\/biomolther.2025.208","type":"journal-article","created":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T08:40:20Z","timestamp":1777538420000},"page":"565-577","update-policy":"https:\/\/doi.org\/10.4062\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["The RIPK3 Inhibitor GSK872 Attenuates Inflammation and Necroptosis via Modulation of the JNK Signaling Pathway in LPS-Stimulated Microglia"],"prefix":"10.4062","volume":"34","author":[{"given":"Jin-Sun","family":"Park","sequence":"first","affiliation":[{"name":"Department of Molecular Medicine, Inflammation-Cancer Microenvironment Research Center, School of Medicine, Ewha Womans University, Seoul 07804, Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Do-Yeon","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Molecular Medicine, Inflammation-Cancer Microenvironment Research Center, School of Medicine, Ewha Womans University, Seoul 07804, Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Seong-Eun","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Molecular Medicine, Inflammation-Cancer Microenvironment Research Center, School of Medicine, Ewha Womans University, Seoul 07804, Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jin-Won","family":"Hyun","sequence":"additional","affiliation":[{"name":"Department of Biochemistry, College of Medicine, and Jeju Research Center for Natural Medicine, Jeju National University, Jeju 63243, Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hee-Sun","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Molecular Medicine, Inflammation-Cancer Microenvironment Research Center, School of Medicine, Ewha Womans University, Seoul 07804, Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2506","published-online":{"date-parts":[[2026,4,30]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1111\/acel.13814"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1038\/nn.4608"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1038\/s41419-018-1189-2"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1186\/s12967-018-1606-4"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopha.2018.08.056"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1016\/bs.ircmb.2019.12.006"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1186\/s12876-022-02208-x"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1038\/s41392-023-01588-0"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1038\/cdd.2017.65"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1016\/j.expneurol.2020.113374"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1016\/j.jstrokecerebrovasdis.2021.106213"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1186\/s12974-022-02406-0"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1016\/j.celrep.2018.01.089"},{"key":"ref14","unstructured":"Institute and for Laboratory Animal Research (2011) Guide for the Care and Use of Laboratory Animals, 8th ed. National Academies Press, Washington (DC)."},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1016\/j.molcel.2017.02.024"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1038\/srep39914"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1016\/j.molcel.2014.10.021"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1038\/s12276-022-00868-z"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1016\/bs.ircmb.2016.08.007"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1016\/j.immuni.2016.06.007"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1186\/s13024-025-00867-4"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1016\/j.celrep.2015.02.051"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1038\/s41418-019-0408-4"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuint.2024.105896"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.1016\/j.jneuroim.2009.01.020"},{"key":"ref26","doi-asserted-by":"publisher","DOI":"10.3390\/cells9020383"},{"key":"ref27","doi-asserted-by":"publisher","DOI":"10.1038\/cddis.2013.531"},{"key":"ref28","doi-asserted-by":"publisher","DOI":"10.3389\/fcell.2019.00393"},{"key":"ref29","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2025.1480027"},{"key":"ref30","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2021.701564"},{"key":"ref31","doi-asserted-by":"publisher","DOI":"10.3233\/JAD-220809"},{"key":"ref32","doi-asserted-by":"publisher","DOI":"10.1038\/cddis.2017.286"}],"container-title":["Biomolecules &amp; Therapeutics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pdf.medrang.co.kr\/BT2\/2026\/034\/BT034-03-565.pdf","content-type":"unspecified","content-version":"tdm","intended-application":"text-mining"},{"URL":"https:\/\/pdf.medrang.co.kr\/BT2\/2026\/034\/BT034-03-565.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,14]],"date-time":"2026-05-14T06:06:32Z","timestamp":1778738792000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.biomolther.org\/journal\/view.html?doi=10.4062\/biomolther.2025.208"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4,30]]},"references-count":32,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2026,5,1]]}},"alternative-id":["10.4062\/biomolther.2025.208"],"URL":"https:\/\/doi.org\/10.4062\/biomolther.2025.208","relation":{},"ISSN":["1976-9148","2005-4483"],"issn-type":[{"value":"1976-9148","type":"print"},{"value":"2005-4483","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,4,30]]},"assertion":[{"value":"http:\/\/www.biomolther.org\/journal\/view.html?doi=10.4062\/biomolther.2025.208","URL":"http:\/\/www.biomolther.org\/journal\/view.html?doi=10.4062\/biomolther.2025.208","name":"the_journal","label":"Biomolecules & Therapeutics","group":{"name":"multiple_resolution","label":"Full text available at:"}},{"value":"2025-10-22","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-01-12","order":1,"name":"revised","label":"Revised","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-01-28","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-04-30","order":3,"name":"published","label":"Online First","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-05-01","order":4,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}},{"value":"\u00a9 2026 The Korean Society of Applied Pharmacology","name":"copyright","label":"Copyright","group":{"name":"Copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.","name":"license","label":"License","explanation":{"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},"group":{"name":"Copyright_and_licensing","label":"Copyright and Licensing"}}]}}