{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T16:48:01Z","timestamp":1789145281286,"version":"build-2803163510"},"reference-count":20,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[1995,4,1]],"date-time":"1995-04-01T00:00:00Z","timestamp":796694400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Mayo Clinic Proceedings"],"published-print":{"date-parts":[[1995,4]]},"DOI":"10.4065\/70.4.327","type":"journal-article","created":{"date-parts":[[2009,1,23]],"date-time":"2009-01-23T20:01:56Z","timestamp":1232740916000},"page":"327-330","source":"Crossref","is-referenced-by-count":74,"title":["Severe Hypercapnia After Low-Flow Oxygen Therapy in Patients With Neuromuscular Disease and Diaphragmatic Dysfunction"],"prefix":"10.4065","volume":"70","author":[{"given":"Peter C.","family":"Gay","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lee C.","family":"Edmonds","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.4065\/70.4.327_bib1","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1164\/arrd.1980.121.3.587","article-title":"Determinants of hypoventilation during wakefulness and sleep in diaphragmatic paralysis","volume":"121","author":"Skatrud","year":"1980","journal-title":"Am Rev Respir Dis"},{"key":"10.4065\/70.4.327_bib2","doi-asserted-by":"crossref","first-page":"907","DOI":"10.1164\/arrd.1987.135.4.907","article-title":"Hyperoxic-induced hypercapnia in stable chronic obstructive pulmonary disease","volume":"135","author":"Sassoon","year":"1987","journal-title":"Am Rev Respir Dis"},{"key":"10.4065\/70.4.327_bib3","doi-asserted-by":"crossref","first-page":"874","DOI":"10.1056\/NEJM198404053101402","article-title":"Effect of carbon dioxide on diaphragmatic function in human beings","volume":"310","author":"Juan","year":"1984","journal-title":"N Engl J Med"},{"key":"10.4065\/70.4.327_bib4","doi-asserted-by":"crossref","first-page":"616","DOI":"10.1136\/thx.38.8.616","article-title":"Respiratory muscle and pulmonary function in polymyositis and other proximal myopathies","volume":"38","author":"Braun","year":"1983","journal-title":"Thorax"},{"key":"10.4065\/70.4.327_bib5","first-page":"641","article-title":"Maximal static respiratory pressures in generalized neuromuscular disease","volume":"103","author":"Black","year":"1971","journal-title":"Am Rev Respir Dis"},{"key":"10.4065\/70.4.327_bib6","doi-asserted-by":"crossref","first-page":"686","DOI":"10.1016\/S0025-6196(12)62080-1","article-title":"The effects of alteration in pulmonary function and sleep parameters on survival in patients with amyotrophic lateral sclerosis","volume":"66","author":"Gay","year":"1991","journal-title":"Mayo Clin Proc"},{"key":"10.4065\/70.4.327_bib7","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1378\/chest.88.2.211","article-title":"Electro-physiologic evaluation of phrenic nerves in severe respiratory insufficiency requiring mechanical ventilation","volume":"88","author":"Moorthy","year":"1985","journal-title":"Chest"},{"key":"10.4065\/70.4.327_bib8","first-page":"589","article-title":"Mean and instantaneous expiratory flows, FVC and FEV1,: prediction equations from a probability sample of Michigan, a large industrial state","volume":"22","author":"Miller","year":"1986","journal-title":"Bull Eur Physiopathol Respir"},{"key":"10.4065\/70.4.327_bib9","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1164\/ajrccm\/141.1.43","article-title":"Oxygen desaturation during sleep as a function of the underlying respiratory disease","volume":"141","author":"Midgren","year":"1990","journal-title":"Am Rev Respir Dis"},{"key":"10.4065\/70.4.327_bib10","doi-asserted-by":"crossref","first-page":"811","DOI":"10.1378\/chest.94.4.811","article-title":"Noninvasive ventilatory support during sleep improves respiratory failure in kyphoscoliosis","volume":"94","author":"Ellis","year":"1988","journal-title":"Chest"},{"key":"10.4065\/70.4.327_bib11","first-page":"758","article-title":"Hypercapnic ventilatory response in sleeping adults","volume":"126","author":"Douglas","year":"1982","journal-title":"Am Rev Respir Dis"},{"key":"10.4065\/70.4.327_bib12","doi-asserted-by":"crossref","first-page":"1125","DOI":"10.1212\/WNL.27.12.1125","article-title":"Ventilatory response in myotonic dystrophy","volume":"27","author":"Carroll","year":"1977","journal-title":"Neurology"},{"key":"10.4065\/70.4.327_bib13","first-page":"87","article-title":"Diaphragm function and alveolar hypoventilation","volume":"45","author":"Davis","year":"1976","journal-title":"QJMed"},{"key":"10.4065\/70.4.327_bib14","doi-asserted-by":"crossref","first-page":"874","DOI":"10.1164\/ajrccm\/138.4.874","article-title":"Breathing pattern and eye movement density during REM sleep in humans","volume":"138","author":"Gould","year":"1988","journal-title":"Am Rev Respir Dis"},{"key":"10.4065\/70.4.327_bib15","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1016\/0002-9343(77)90286-8","article-title":"Blunted respiratory drive in congenital myopathy","volume":"63","author":"Riley","year":"1977","journal-title":"Am J Med"},{"key":"10.4065\/70.4.327_bib16","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1378\/chest.97.1.91","article-title":"Long-term follow-up of nocturnal ventilatory assistance in patients with respiratory failure due to Duchenne-type muscular dystrophy","volume":"97","author":"Mohr","year":"1990","journal-title":"Chest"},{"key":"10.4065\/70.4.327_bib17","first-page":"A322","article-title":"Nasal positive pressure ventilation can be used successfully at home to control nocturnal hypoventilation in COPD [abstract]","volume":"141","author":"Elliott","year":"1990","journal-title":"Am Rev Respir Dis"},{"key":"10.4065\/70.4.327_bib18","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1164\/ajrccm\/136.1.188","article-title":"Treatment of alveolar hypoventilation in a six-year-old girl with intermittent positive pressure ventilation through a nose mask","volume":"136","author":"Ellis","year":"1987","journal-title":"Am Rev Respir Dis"},{"key":"10.4065\/70.4.327_bib19","first-page":"240","article-title":"Nighttime ventilation improves respiratory failure in secondary kyphoscoliosis","volume":"129","author":"Hoeppner","year":"1984","journal-title":"Am Rev Respir Dis"},{"key":"10.4065\/70.4.327_bib20","doi-asserted-by":"crossref","first-page":"695","DOI":"10.1016\/S0025-6196(12)62081-3","article-title":"Nocturnal nasal ventilation for treatment of patients with hypercapnic respiratory failure","volume":"66","author":"Gay","year":"1991","journal-title":"Mayo Clin Proc"}],"container-title":["Mayo Clinic Proceedings"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0025619611634101?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0025619611634101?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,12,22]],"date-time":"2018-12-22T03:54:31Z","timestamp":1545450871000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0025619611634101"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1995,4]]},"references-count":20,"journal-issue":{"issue":"4","published-print":{"date-parts":[[1995,4]]}},"alternative-id":["S0025619611634101"],"URL":"https:\/\/doi.org\/10.4065\/70.4.327","relation":{},"ISSN":["0025-6196"],"issn-type":[{"value":"0025-6196","type":"print"}],"subject":[],"published":{"date-parts":[[1995,4]]}}}