{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T23:29:27Z","timestamp":1790724567911,"version":"4.1.0"},"reference-count":33,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[1999,5,1]],"date-time":"1999-05-01T00:00:00Z","timestamp":925516800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Mayo Clinic Proceedings"],"published-print":{"date-parts":[[1999,5]]},"DOI":"10.4065\/74.5.481","type":"journal-article","created":{"date-parts":[[2009,1,24]],"date-time":"2009-01-24T01:16:10Z","timestamp":1232759770000},"page":"481-484","source":"Crossref","is-referenced-by-count":9,"title":["Scleromyxedema: A Complete Response to Prednisone"],"prefix":"10.4065","volume":"74","author":[{"given":"Daniel","family":"Rayson","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John A.","family":"Lust","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alan","family":"Duncan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"W.P. Daniel","family":"Su","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.4065\/74.5.481_bib1","doi-asserted-by":"crossref","first-page":"1974","DOI":"10.1001\/archinte.1984.04400010082016","article-title":"The acquired cutaneous mucinoses","volume":"144","author":"Matsuoka","year":"1984","journal-title":"Arch Intern Med"},{"key":"10.4065\/74.5.481_bib2","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1038\/jid.1953.25","article-title":"Lichen myxedematosus {differentiation from cutaneous myxedemas or mucoid statesl","volume":"20","author":"Montgomery","year":"1953","journal-title":"Invest Dermatot"},{"key":"10.4065\/74.5.481_bib3","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0190-9622(86)70001-7","article-title":"The cutaneous mucinoses","volume":"14","author":"Truhani","year":"1986","journal-title":"J Am Acad Dermatol"},{"key":"10.4065\/74.5.481_bib4","first-page":"549","article-title":"Scleromyxedema","volume":"24","author":"Chanda","year":"1979","journal-title":"Cutis"},{"key":"10.4065\/74.5.481_bib5","first-page":"201","article-title":"The dermal mucinoses","volume":"8","author":"Stephens","year":"1993","journal-title":"Adv Dermatol"},{"key":"10.4065\/74.5.481_bib6","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1111\/j.1365-4362.1989.tb02437.x","article-title":"Scleromyxedema","volume":"28","author":"Harris","year":"1989","journal-title":"Int J Dermatol"},{"key":"10.4065\/74.5.481_bib7","doi-asserted-by":"crossref","first-page":"779 782","DOI":"10.1093\/rheumatology\/31.11.779","article-title":"Papular mucinosis {scleromyxoedema) complicating diffuse systemic sclerosis: clinical features and electron microscope observations","volume":"31","author":"Varga","year":"1992","journal-title":"Br J Rheumatol"},{"key":"10.4065\/74.5.481_bib8","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1097\/00005792-198801000-00004","article-title":"Scleromyxedema: a scleroderma-like disorder with systemic manifestations","volume":"67","author":"Gabriel","year":"1988","journal-title":"Medicine"},{"key":"10.4065\/74.5.481_bib9","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1111\/j.1365-4362.1989.tb02436.x","article-title":"Scleromyxedema and severe myositis","volume":"28","author":"Rothe","year":"1989","journal-title":"Int J Dermatol"},{"key":"10.4065\/74.5.481_bib10","first-page":"545","article-title":"Scleromyxedema associated with arthritis and myopathy: a case report","volume":"11","author":"Espinosa","year":"1993","journal-title":"Clin Exp Rheumatol"},{"key":"10.4065\/74.5.481_bib11","doi-asserted-by":"crossref","first-page":"446","DOI":"10.1093\/ajcp\/69.4.446","article-title":"Scleromyxedema myopathy: histochemical and electron microscopic observations","volume":"69","author":"Verity","year":"1978","journal-title":"Am J Clin Pathol"},{"key":"10.4065\/74.5.481_bib12","first-page":"471","article-title":"Acute cerebral symptomatology, a rare presentation of scleromyxedema","volume":"39","author":"Ochitill","year":"1978","journal-title":"J Clin Psychiatry"},{"key":"10.4065\/74.5.481_bib13","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/0190-9622(93)70021-K","article-title":"The association of poten tially lethal neurologic syndromes with scleromyxedema (papular mucinosis)","volume":"28","author":"Webster","year":"1993","journal-title":"J Am Acad Dermatol"},{"key":"10.4065\/74.5.481_bib14","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1001\/archderm.1956.01550090033007","article-title":"Autopsy findings in lichen myx-edematosus","volume":"74","author":"McCulstion","year":"1956","journal-title":"Arch Dermatol"},{"key":"10.4065\/74.5.481_bib15","doi-asserted-by":"crossref","first-page":"446","DOI":"10.1001\/archderm.1964.01590270132030","article-title":"An abnormal serum globulin in lichen myxedematosus","volume":"89","author":"McCarthy","year":"1964","journal-title":"Arch Dermatol"},{"key":"10.4065\/74.5.481_bib16","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1001\/archderm.1976.01630250031009","article-title":"Successful management of lichen myxedematosus: report of a case","volume":"112","author":"Hill","year":"1976","journal-title":"Arch Dermatol"},{"key":"10.4065\/74.5.481_bib17","doi-asserted-by":"crossref","first-page":"3743","DOI":"10.1016\/0190-9622(95)90007-1","article-title":"Scleromyxedema","volume":"33","author":"Dinneen","year":"1995","journal-title":"J Am Acad Dermatol"},{"key":"10.4065\/74.5.481_bib18","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1016\/S0025-7125(16)30974-9","article-title":"Myeloma, paraproteinemias, and the skin","volume":"70","author":"Plette","year":"1986","journal-title":"Med Clin North Am"},{"key":"10.4065\/74.5.481_bib19","first-page":"189","article-title":"Scleromyxedema associated with IgG lambda multiple myeloma","volume":"50","author":"Mutdrow","year":"1983","journal-title":"CleveClmQ"},{"key":"10.4065\/74.5.481_bib20","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1126\/science.622555","article-title":"Lichen myxedematosus serum stimulates human skin fibroblast proliferation","volume":"199","author":"Harper","year":"1978","journal-title":"Science"},{"key":"10.4065\/74.5.481_bib21","first-page":"171","article-title":"Lichen myxedematosus (scleromyxedema) serum stimulates hyaluronic acid and prostaglandin E production by human fibroblasts","volume":"12","author":"Yaron","year":"1985","journal-title":"J Rheumatol"},{"key":"10.4065\/74.5.481_bib22","first-page":"837","article-title":"Scleromyxedema serum increases proliferation but not the glycosami-noglycan synthesis of derma I fibroblasts","volume":"16","author":"Ferrarinl","year":"1989","journal-title":"J Rheumatol"},{"key":"10.4065\/74.5.481_bib23","doi-asserted-by":"crossref","first-page":"1733","DOI":"10.1001\/archderm.1991.01680100137029","article-title":"Regression of scleromyxedema with topical betamethasone and dimethyl sulfoxide: a 30 month fDllowup [letter]","volume":"127","author":"Bonnetbianc","year":"1991","journal-title":"Arch Dermatol"},{"key":"10.4065\/74.5.481_bib24","doi-asserted-by":"crossref","first-page":"724","DOI":"10.1016\/S0190-9622(08)80676-7","article-title":"Extracorporeal photochemotherapy: a potentially useful treatment for scleromyxedema","volume":"25","author":"Berkson","year":"1991","journal-title":"J Am Acad Dermatol"},{"key":"10.4065\/74.5.481_bib25","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1111\/j.1365-2133.1984.tb04642.x","article-title":"PUVA treatment of scleromyxoedema","volume":"110","author":"Farr","year":"1984","journal-title":"Er i Dermatol"},{"key":"10.4065\/74.5.481_bib26","doi-asserted-by":"crossref","first-page":"854","DOI":"10.1016\/0190-9622(91)70132-L","article-title":"Improvement of scleromyxedema associated with isotretinoin therapy","volume":"24","author":"Hlsler","year":"1991","journal-title":"J Am Acad Dermatol"},{"key":"10.4065\/74.5.481_bib27","doi-asserted-by":"crossref","first-page":"651","DOI":"10.1111\/j.1365-2133.1987.tb07499.x","article-title":"Sclero myxoadema-successful treatment with plasma exchange and immu-nosuppression","volume":"117","author":"Macfarlane","year":"1987","journal-title":"Br J Dermatol"},{"key":"10.4065\/74.5.481_bib28","doi-asserted-by":"crossref","first-page":"842","DOI":"10.1016\/S0190-9622(08)81176-0","article-title":"Successful treatment of scleromyxedema with plasmapheresis and immunosuppression","volume":"22","author":"Keong","year":"1990","journal-title":"J Am Acad Dermatol"},{"key":"10.4065\/74.5.481_bib29","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1111\/j.1524-4725.1993.tb00375.x","article-title":"Lichen myxedematosus treated with chiorambucil","volume":"19","author":"Wieder","year":"1993","journal-title":"J Dermatol Surg Oncol"},{"key":"10.4065\/74.5.481_bib30","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1016\/S0190-9622(96)90650-7","article-title":"Treatment of scleromyxedema with 2-chlorodeoxyadenosine","volume":"35","author":"Davis","year":"1996","journal-title":"J Am Acad Dermatol"},{"key":"10.4065\/74.5.481_bib31","doi-asserted-by":"crossref","first-page":"727","DOI":"10.1111\/j.1365-2133.1979.tb08080.x","article-title":"Spontaneous resolution of lichen myxoedematosus","volume":"100","author":"Hardie","year":"1979","journal-title":"Br J Dermatol"},{"key":"10.4065\/74.5.481_bib32","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1001\/archderm.1969.01610190057010","article-title":"Scleromyxedema: a dramatic response to melphalan","volume":"99","author":"Feldman","year":"1969","journal-title":"Arch Dermatol"},{"key":"10.4065\/74.5.481_bib33","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1001\/archderm.1979.04010030003002","article-title":"Treatment of scleromyxedema with melphalan","volume":"115","author":"Harr","year":"1979","journal-title":"Arch Dermatol"}],"container-title":["Mayo Clinic Proceedings"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0025619611651288?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0025619611651288?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,12,22]],"date-time":"2018-12-22T08:51:28Z","timestamp":1545468688000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0025619611651288"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1999,5]]},"references-count":33,"journal-issue":{"issue":"5","published-print":{"date-parts":[[1999,5]]}},"alternative-id":["S0025619611651288"],"URL":"https:\/\/doi.org\/10.4065\/74.5.481","relation":{},"ISSN":["0025-6196"],"issn-type":[{"value":"0025-6196","type":"print"}],"subject":[],"published":{"date-parts":[[1999,5]]}}}