{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,8]],"date-time":"2026-07-08T00:41:52Z","timestamp":1783471312893,"version":"3.55.0"},"reference-count":110,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2003,5,1]],"date-time":"2003-05-01T00:00:00Z","timestamp":1051747200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Mayo Clinic Proceedings"],"published-print":{"date-parts":[[2003,5]]},"DOI":"10.4065\/78.5.589","type":"journal-article","created":{"date-parts":[[2009,1,24]],"date-time":"2009-01-24T01:20:27Z","timestamp":1232760027000},"page":"589-598","source":"Crossref","is-referenced-by-count":172,"title":["Hepatic Veno-occlusive Disease (Sinusoidal Obstruction Syndrome) After Hematopoietic Stem Cell Transplantation"],"prefix":"10.4065","volume":"78","author":[{"given":"Shaji","family":"Kumar","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laurie D.","family":"Deleve","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrick S.","family":"Kamath","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ayalew","family":"Tefferi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.4065\/78.5.589_bib1","doi-asserted-by":"crossref","first-page":"848","DOI":"10.1016\/S0140-6736(01)00020-4","article-title":"Senecio disease, or cirrhosis of the liver due to Senecio poisoning","volume":"2","author":"Willmot","year":"1920","journal-title":"Lancet"},{"key":"10.4065\/78.5.589_bib2","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1055\/s-2002-23204","article-title":"Toxic injury to hepatic sinusoids: sinusoidal obstruction syndrome (veno-occlusive disease)","volume":"22","author":"DeLeve","year":"2002","journal-title":"Semin Liver Dis"},{"key":"10.4065\/78.5.589_bib3","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1136\/pgmj.54.634.511","article-title":"Herbal medicines and veno-occlusive disease in India","volume":"54","author":"Datta","year":"1978","journal-title":"Postgrad Med J"},{"key":"10.4065\/78.5.589_bib4","doi-asserted-by":"crossref","first-page":"849","DOI":"10.1136\/gut.17.11.849","article-title":"Study of an epidemic of venoocclusive disease in India","volume":"17","author":"Tandon","year":"1976","journal-title":"Gut"},{"key":"10.4065\/78.5.589_bib5","doi-asserted-by":"crossref","first-page":"158","DOI":"10.7326\/0003-4819-90-2-158","article-title":"Veno-occlusive disease of the liver after allogeneic bone marrow transplantation: possible association with graft-versus-host disease","volume":"90","author":"Berk","year":"1979","journal-title":"Ann Intern Med"},{"key":"10.4065\/78.5.589_bib6","first-page":"5","article-title":"Fatal veno-occlusive disease of the liver after chemotherapy, whole-body irradiation and bone marrow transplantation for refractory acute leukaemia","volume":"55","author":"Jacobs","year":"1979","journal-title":"S Afr Med J"},{"key":"10.4065\/78.5.589_bib7","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1002\/hep.1840040121","article-title":"Venocclusive disease of the liver after bone marrow transplantation: diagnosis, incidence, and predisposing factors","volume":"4","author":"McDonald","year":"1984","journal-title":"Hepatology"},{"key":"10.4065\/78.5.589_bib8","doi-asserted-by":"crossref","first-page":"1178","DOI":"10.1016\/0016-5085(80)90911-7","article-title":"An analysis of hepatic venocclusive disease and centrilobular hepatic degeneration following bone marrow transplantation","volume":"79","author":"Shulman","year":"1980","journal-title":"Gastroenterology"},{"key":"10.4065\/78.5.589_bib9","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/0268-960X(93)90023-W","article-title":"Hepatic veno-occlusive disease after bone marrow transplant","volume":"7","author":"Carreras","year":"1993","journal-title":"Blood Rev"},{"key":"10.4065\/78.5.589_bib10","doi-asserted-by":"crossref","first-page":"2435","DOI":"10.1002\/(SICI)1097-0142(19970615)79:12<2435::AID-CNCR21>3.0.CO;2-R","article-title":"Venoocclusive disease of the liver after chemotherapy with vincristine, actinomycin D, and cyclophosphamide for the treatment of rhabdomyosarcoma: a report of the Intergroup Rhabdomyosarcoma Study Group","volume":"79","author":"Ortega","year":"1997","journal-title":"Cancer"},{"key":"10.4065\/78.5.589_bib11","first-page":"273","article-title":"Pathophysiological aspects of dacarbazine-induced human liver damage","volume":"32","author":"Paschke","year":"1985","journal-title":"Hepatogastroenterology"},{"key":"10.4065\/78.5.589_bib12","doi-asserted-by":"crossref","first-page":"1017","DOI":"10.1016\/S0190-9622(08)80659-7","article-title":"6-Thioguanine therapy for psoriasis causing toxic hepatic venoocclusive disease","volume":"28","author":"Kao","year":"1993","journal-title":"J Am Acad Dermatol"},{"key":"10.4065\/78.5.589_bib13","doi-asserted-by":"crossref","first-page":"651","DOI":"10.7326\/0003-4819-104-5-651","article-title":"Hepatic venoocclusive disease associated with renal transplantation and azathioprine therapy","volume":"104","author":"Read","year":"1986","journal-title":"Ann Intern Med"},{"key":"10.4065\/78.5.589_bib14","doi-asserted-by":"crossref","first-page":"406","DOI":"10.1002\/1097-0142(20010715)92:2<406::AID-CNCR1336>3.0.CO;2-U","article-title":"Mylotarg (gemtuzumab ozogamicin) therapy is associated with hepatic venoocclusive disease in patients who have not received stem cell transplantation","volume":"92","author":"Giles","year":"2001","journal-title":"Cancer"},{"key":"10.4065\/78.5.589_bib15","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1002\/(SICI)1096-911X(199710)29:4<245::AID-MPO2>3.0.CO;2-M","article-title":"Veno-occlusive disease of the liver in children treated for Wilms tumor","volume":"29","author":"Bisogno","year":"1997","journal-title":"Med Pediatr Oncol"},{"key":"10.4065\/78.5.589_bib16","doi-asserted-by":"crossref","first-page":"1144","DOI":"10.1002\/hep.510300514","article-title":"\u201cSilent\u201d presentation of veno-occlusive disease after liver transplantation as part of the process of cellular rejection with endothelial predilection","volume":"30","author":"Sebagh","year":"1999","journal-title":"Hepatology"},{"key":"10.4065\/78.5.589_bib17","doi-asserted-by":"crossref","first-page":"255","DOI":"10.7326\/0003-4819-118-4-199302150-00003","article-title":"Veno-occlusive disease of the liver and multiorgan failure after bone marrow transplantation: a cohort study of 355 patients","volume":"118","author":"McDonald","year":"1993","journal-title":"Ann Intern Med"},{"key":"10.4065\/78.5.589_bib18","first-page":"197","article-title":"Hepatic veno-occlusive disease\u2014liver toxicity syndrome after bone marrow transplantation","volume":"10","author":"Shulman","year":"1992","journal-title":"Bone Marrow Transplant"},{"key":"10.4065\/78.5.589_bib19","first-page":"3599","article-title":"Incidence and outcome of hepatic veno-occlusive disease after blood or marrow transplantation: a prospective cohort study of the European Group for Blood and Marrow Transplantation","volume":"92","author":"Carreras","year":"1998","journal-title":"Blood"},{"key":"10.4065\/78.5.589_bib20","doi-asserted-by":"crossref","first-page":"778","DOI":"10.1097\/00007890-198712000-00011","article-title":"Venoocclusive disease of the liver following bone marrow transplantation","volume":"44","author":"Jones","year":"1987","journal-title":"Transplantation"},{"key":"10.4065\/78.5.589_bib21","doi-asserted-by":"crossref","first-page":"1171","DOI":"10.1002\/hep.1840190515","article-title":"Veno-occlusive disease of the liver after marrow transplantation: histological correlates of clinical signs and symptoms","volume":"19","author":"Shulman","year":"1994","journal-title":"Hepatology"},{"key":"10.4065\/78.5.589_bib22","first-page":"549","article-title":"Hepatic veno-occlusive disease after bone marrow transplantation: immunohistochemical identification of the material within occluded central venules","volume":"127","author":"Shulman","year":"1987","journal-title":"Am J Pathol"},{"key":"10.4065\/78.5.589_bib23","doi-asserted-by":"crossref","first-page":"1779","DOI":"10.1002\/hep.510290615","article-title":"Characterization of a reproducible rat model of hepatic veno-occlusive disease","volume":"29","author":"DeLeve","year":"1999","journal-title":"Hepatology"},{"key":"10.4065\/78.5.589_bib24","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1055\/s-2007-1007333","article-title":"Hepatic microvasculature: dynamic structure and its regulation","volume":"13","author":"McCuskey","year":"1993","journal-title":"Semin Liver Dis"},{"key":"10.4065\/78.5.589_bib25","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1034\/j.1600-0676.2000.020001003.x","article-title":"Morphological mechanisms for regulating blood flow through hepatic sinusoids","volume":"20","author":"McCuskey","year":"2000","journal-title":"Liver"},{"key":"10.4065\/78.5.589_bib26","first-page":"39","article-title":"Changes in the natural anticoagulants following bone marrow transplantation","volume":"5","author":"Harper","year":"1990","journal-title":"Bone Marrow Transplant"},{"key":"10.4065\/78.5.589_bib27","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1016\/0049-3848(91)90176-W","article-title":"Liver venoocclusive disease after bone marrow transplantation changes in coagulation parameters and endothelial markers","volume":"63","author":"Scrobohaci","year":"1991","journal-title":"Thromb Res"},{"key":"10.4065\/78.5.589_bib28","first-page":"519","article-title":"Early hemostatic alterations following bone marrow transplantation: a prospective study","volume":"79","author":"Vannucchi","year":"1994","journal-title":"Haematologica"},{"key":"10.4065\/78.5.589_bib29","doi-asserted-by":"crossref","first-page":"233","DOI":"10.3109\/10428199709114163","article-title":"Venocclusive disease of the liver after bone marrow transplantation: the role of hemostasis","volume":"25","author":"Faioni","year":"1997","journal-title":"Leuk LymphomA"},{"key":"10.4065\/78.5.589_bib30","first-page":"253","article-title":"Hypercoagulability in patients undergoing autologous or allogeneic BMT for hematological malignancies","volume":"12","author":"Catani","year":"1993","journal-title":"Bone Marrow Transplant"},{"key":"10.4065\/78.5.589_bib31","first-page":"499","article-title":"von Willebrand factor as a marker of endothelial cell activation following BMT","volume":"10","author":"Collins","year":"1992","journal-title":"Bone Marrow Transplant"},{"key":"10.4065\/78.5.589_bib32","first-page":"383","article-title":"Increased plasma level of vascular endothelial glycoprotein thrombomodulin as an early indicator of endothelial damage in bone marrow transplantation","volume":"18","author":"Testa","year":"1996","journal-title":"Bone Marrow Transplant"},{"key":"10.4065\/78.5.589_bib33","first-page":"277","article-title":"Endothelium and bone marrow transplantation","volume":"17","author":"Catani","year":"1996","journal-title":"Bone Marrow Transplant"},{"key":"10.4065\/78.5.589_bib34","doi-asserted-by":"crossref","first-page":"1011","DOI":"10.1182\/blood.V75.4.1011.1011","article-title":"Increased serum levels of tumor necrosis factor alpha precede major complications of bone marrow transplantation","volume":"75","author":"Holler","year":"1990","journal-title":"Blood"},{"key":"10.4065\/78.5.589_bib35","doi-asserted-by":"crossref","first-page":"1205","DOI":"10.1182\/blood.V78.5.1205.1205","article-title":"Phase I-II trial of pentoxifylline for the prevention of transplant-related toxicities following bone marrow transplantation [published correction appears in Blood. 1992;79:3397]","volume":"78","author":"Bianco","year":"1991","journal-title":"Blood"},{"key":"10.4065\/78.5.589_bib36","doi-asserted-by":"crossref","first-page":"1014","DOI":"10.1097\/00007890-199112000-00015","article-title":"Hepatic dysfunction following T-cell-depleted allogeneic bone marrow transplantation","volume":"52","author":"Soiffer","year":"1991","journal-title":"Transplantation"},{"key":"10.4065\/78.5.589_bib37","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1046\/j.1365-2559.1999.00569.x","article-title":"Hepatic stellate cells (Ito cells) in veno-occlusive disease of the liver after allogeneic bone marrow transplantation","volume":"34","author":"Sato","year":"1999","journal-title":"Histopathology"},{"key":"10.4065\/78.5.589_bib38","doi-asserted-by":"crossref","first-page":"1699","DOI":"10.1200\/JCO.1990.8.10.1699","article-title":"Hepatic venoocclusive disease in autologous bone marrow transplantation of solid tumors and lymphomas","volume":"8","author":"Ayash","year":"1990","journal-title":"J Clin Oncol"},{"key":"10.4065\/78.5.589_bib39","doi-asserted-by":"crossref","first-page":"1998","DOI":"10.1182\/blood.V83.7.1998.1998","article-title":"Hepatitis C virus infection is a risk factor for liver failure from veno-occlusive disease after bone marrow transplantation","volume":"83","author":"Frickhofen","year":"1994","journal-title":"Blood"},{"key":"10.4065\/78.5.589_bib40","doi-asserted-by":"crossref","first-page":"1486","DOI":"10.1097\/00007890-199911270-00010","article-title":"The role of hepatitis C and B virus infections as risk factors for severe liver complications following allogeneic BMT: a prospective study by the Infectious Disease Working Party of the European Blood and Marrow Transplantation Group","volume":"68","author":"Locasciulli","year":"1999","journal-title":"Transplantation"},{"key":"10.4065\/78.5.589_bib41","doi-asserted-by":"crossref","first-page":"1893","DOI":"10.1002\/hep.510290609","article-title":"Hepatitis C virus infection and bone marrow transplantation: a cohort study with 10-year follow-up","volume":"29","author":"Strasser","year":"1999","journal-title":"Hepatology"},{"key":"10.4065\/78.5.589_bib42","doi-asserted-by":"crossref","first-page":"3458","DOI":"10.1182\/blood.V81.12.3458.3458","article-title":"Naturally occurring anticoagulants and bone marrow transplantation: plasma protein C predicts the development of venocclusive disease of the liver","volume":"81","author":"Faioni","year":"1993","journal-title":"Blood"},{"key":"10.4065\/78.5.589_bib43","doi-asserted-by":"crossref","first-page":"1110","DOI":"10.1038\/sj.bmt.1702390","article-title":"Factor V Leiden mutation as a predisposing factor for veno-occlusive disease following BMT [letter]","volume":"25","author":"Ertem","year":"2000","journal-title":"Bone Marrow Transplant"},{"key":"10.4065\/78.5.589_bib44","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1038\/sj.bmt.1701952","article-title":"The prothrombin gene variant G20210A but not factor V Leiden may be associated with veno-occlusive disease following BMT [letter]","volume":"24","author":"Duggan","year":"1999","journal-title":"Bone Marrow Transplant"},{"key":"10.4065\/78.5.589_bib45","doi-asserted-by":"crossref","first-page":"4568","DOI":"10.1182\/blood.V92.12.4568","article-title":"Norethisterone treatment, a major risk-factor for veno-occlusive disease in the liver after allogeneic bone marrow transplantation","volume":"92","author":"H\u00e4gglund","year":"1998","journal-title":"Blood"},{"key":"10.4065\/78.5.589_bib46","first-page":"151","article-title":"Marrow transplantation for acute nonlymphoblastic leukemia in first remission: toxicity and long-term follow-up of patients conditioned with single dose or fractionated total body irradiation","volume":"1","author":"Deeg","year":"1986","journal-title":"Bone Marrow Transplant"},{"key":"10.4065\/78.5.589_bib47","doi-asserted-by":"crossref","first-page":"2723","DOI":"10.1182\/blood.V83.9.2723.2723","article-title":"A randomized trial comparing busulfan with total body irradiation as conditioning in allogeneic marrow transplant recipients with leukemia: a report from the Nordic Bone Marrow Transplantation Group","volume":"83","author":"Ringden","year":"1994","journal-title":"Blood"},{"key":"10.4065\/78.5.589_bib48","first-page":"1","article-title":"Role of PGE1 to prevent veno-occlusive disease of the liver after bone marrow transplantation","volume":"32","author":"Gluckman","year":"1990","journal-title":"Nouv Rev Fr Hematol"},{"key":"10.4065\/78.5.589_bib49","doi-asserted-by":"crossref","first-page":"830","DOI":"10.1002\/hep.510240414","article-title":"Cellular target of cyclophosphamide toxicity in the murine liver: role of glutathione and site of metabolic activation","volume":"24","author":"DeLeve","year":"1996","journal-title":"Hepatology"},{"key":"10.4065\/78.5.589_bib50","doi-asserted-by":"crossref","first-page":"1275","DOI":"10.1002\/1097-0142(19881001)62:7<1275::AID-CNCR2820620705>3.0.CO;2-I","article-title":"Glutathione monoethyl ester can selectively protect liver from high dose BCNU or cyclophosphamide","volume":"62","author":"Teicher","year":"1988","journal-title":"Cancer"},{"key":"10.4065\/78.5.589_bib51","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1055\/s-2008-1040481","article-title":"Importance and regulation of hepatic glutathione","volume":"10","author":"DeLeve","year":"1990","journal-title":"Semin Liver Dis"},{"key":"10.4065\/78.5.589_bib52","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1055\/s-2007-1007173","article-title":"Glutathione defense in non-parenchymal cells","volume":"18","author":"DeLeve","year":"1998","journal-title":"Semin Liver Dis"},{"key":"10.4065\/78.5.589_bib53","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1159\/000028359","article-title":"Role of oxidative stress and glutathione in busulfan toxicity in cultured murine hepatocytes","volume":"60","author":"DeLeve","year":"2000","journal-title":"Pharmacology"},{"key":"10.4065\/78.5.589_bib54","doi-asserted-by":"crossref","first-page":"428","DOI":"10.1002\/hep.510310224","article-title":"Support of sinusoidal endothelial cell glutathione prevents hepatic veno-occlusive disease in the rat","volume":"31","author":"Wang","year":"2000","journal-title":"Hepatology"},{"key":"10.4065\/78.5.589_bib55","first-page":"135","article-title":"Risk factors for hepatic veno-occlusive disease after high-dose busulfan-containing regimens followed by autologous bone marrow transplantation: a study in 136 children","volume":"10","author":"Meresse","year":"1992","journal-title":"Bone Marrow Transplant"},{"key":"10.4065\/78.5.589_bib56","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1007\/BF00694339","article-title":"Pharmacokinetics of busulfan: correlation with veno-occlusive disease in patients undergoing bone marrow transplantation","volume":"25","author":"Grochow","year":"1989","journal-title":"Cancer Chemother Pharmacol"},{"issue":"4, suppl 4","key":"10.4065\/78.5.589_bib57","first-page":"18","article-title":"Busulfan disposition: the role of therapeutic monitoring in bone marrow transplantation induction regimens","volume":"20","author":"Grochow","year":"1993","journal-title":"Semin Oncol"},{"key":"10.4065\/78.5.589_bib58","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1034\/j.1600-0609.2000.9r200.x","article-title":"Veno-occlusive disease of the liver after hemopoietic cell transplantation","volume":"64","author":"Carreras","year":"2000","journal-title":"Eur J Haematol"},{"key":"10.4065\/78.5.589_bib59","first-page":"75","article-title":"Risk factors for hepatic veno-occlusive disease following HLA-identical sibling bone marrow transplants for leukemia","volume":"17","author":"Rozman","year":"1996","journal-title":"Bone Marrow Transplant"},{"key":"10.4065\/78.5.589_bib60","doi-asserted-by":"crossref","first-page":"2784","DOI":"10.1182\/blood.V79.10.2784.2784","article-title":"Marked increase in veno-occlusive disease of the liver associated with methotrexate use for graft-versus-host disease prophylaxis in patients receiving busulfan\/cyclophosphamide","volume":"79","author":"Essell","year":"1992","journal-title":"Blood"},{"key":"10.4065\/78.5.589_bib61","doi-asserted-by":"crossref","first-page":"3005","DOI":"10.1182\/blood.V85.11.3005.bloodjournal85113005","article-title":"The syndrome of hepatic veno-occlusive disease after marrow transplantation","volume":"85","author":"Bearman","year":"1995","journal-title":"Blood"},{"key":"10.4065\/78.5.589_bib62","doi-asserted-by":"crossref","first-page":"891","DOI":"10.1038\/sj.bmt.1701994","article-title":"Late onset veno-occlusive disease following high-dose chemotherapy and stem cell transplantation","volume":"24","author":"Toh","year":"1999","journal-title":"Bone Marrow Transplant"},{"key":"10.4065\/78.5.589_bib63","doi-asserted-by":"crossref","first-page":"1729","DOI":"10.1200\/JCO.1993.11.9.1729","article-title":"Venoocclusive disease of the liver: development of a model for predicting fatal outcome after marrow transplantation","volume":"11","author":"Bearman","year":"1993","journal-title":"J Clin Oncol"},{"key":"10.4065\/78.5.589_bib64","doi-asserted-by":"crossref","first-page":"1773","DOI":"10.1182\/blood.V67.6.1773.1773","article-title":"Thrombocytopenia in venocclusive disease after bone marrow transplantation or chemotherapy","volume":"67","author":"Rio","year":"1986","journal-title":"Blood"},{"key":"10.4065\/78.5.589_bib65","doi-asserted-by":"crossref","first-page":"1125","DOI":"10.1038\/sj.bmt.1701225","article-title":"Association of pulmonary function testing abnormalities and severe veno-occlusive disease of the liver after marrow transplantation","volume":"21","author":"Matute-Bello","year":"1998","journal-title":"Bone Marrow Transplant"},{"key":"10.4065\/78.5.589_bib66","first-page":"685","article-title":"Association of hepatic veno-occlusive disease with interstitial pneumonitis in bone marrow transplant recipients","volume":"4","author":"Wingard","year":"1989","journal-title":"Bone Marrow Transplant"},{"key":"10.4065\/78.5.589_bib67","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1007\/BF01695888","article-title":"On the reliability of clinical criteria for the diagnosis of hepatic veno-occlusive disease","volume":"66","author":"Carreras","year":"1993","journal-title":"Ann Hematol"},{"key":"10.4065\/78.5.589_bib68","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1148\/radiology.204.2.9240551","article-title":"Hepatic veno-occlusive disease after myeloablative treatment and bone marrow transplantation: value of gray-scale and Doppler US in 100 patients","volume":"204","author":"Lassau","year":"1997","journal-title":"Radiology"},{"key":"10.4065\/78.5.589_bib69","doi-asserted-by":"crossref","first-page":"1290","DOI":"10.1007\/s003300000330","article-title":"MR imaging findings in two patients with hepatic veno-occlusive disease following bone marrow transplantation","volume":"10","author":"van den Bosch","year":"2000","journal-title":"Eur Radiol"},{"key":"10.4065\/78.5.589_bib70","doi-asserted-by":"crossref","first-page":"1015","DOI":"10.1097\/00007890-199504150-00017","article-title":"Utility of transvenous liver biopsies and wedged hepatic venous pressure measurements in sixty marrow transplant recipients","volume":"59","author":"Shulman","year":"1995","journal-title":"Transplantation"},{"key":"10.4065\/78.5.589_bib71","first-page":"21","article-title":"Transjugular liver biopsy in BMT","volume":"11","author":"Carreras","year":"1993","journal-title":"Bone Marrow Transplant"},{"key":"10.4065\/78.5.589_bib72","first-page":"655","article-title":"Laparoscopic liver biopsy to evaluate hepatic dysfunction in patients with hematologic malignancies: a useful tool to effect changes in management","volume":"17","author":"Iqbal","year":"1996","journal-title":"Bone Marrow Transplant"},{"key":"10.4065\/78.5.589_bib73","doi-asserted-by":"crossref","first-page":"2184","DOI":"10.1182\/blood.V89.6.2184","article-title":"Plasminogen activator inhibitor-1 confirms the diagnosis of hepatic veno-occlusive disease in patients with hyperbilirubinemia after bone marrow transplantation","volume":"89","author":"Salat","year":"1997","journal-title":"Blood"},{"key":"10.4065\/78.5.589_bib74","doi-asserted-by":"crossref","first-page":"4337","DOI":"10.1182\/blood-2002-04-1216","article-title":"Multi-institutional use of defibrotide in 88 patients after stem cell transplantation with severe veno-occlusive disease and multisystem organ failure: response without significant toxicity in a high-risk population and factors predictive of outcome","volume":"100","author":"Richardson","year":"2002","journal-title":"Blood"},{"key":"10.4065\/78.5.589_bib75","first-page":"372","article-title":"Increased lung uptake on technetium-99m-sulfur colloid liver-spleen scans in patients with hepatic venoocclusive disease following bone marrow transplantation","volume":"31","author":"Jacobson","year":"1990","journal-title":"J Nucl Med"},{"key":"10.4065\/78.5.589_bib76","first-page":"471","article-title":"N-terminal peptide of type III procollagen: a marker for the development of hepatic venoocclusive disease after BMT and a basis for determining the timing of prophylactic heparin","volume":"11","author":"Rio","year":"1993","journal-title":"Bone Marrow Transplant"},{"key":"10.4065\/78.5.589_bib77","first-page":"439","article-title":"Veno-occlusive disease of the liver complicating ABMT successfully treated with recombinant tissue plasminogen activator (rt-PA)","volume":"5","author":"Baglin","year":"1990","journal-title":"Bone Marrow Transplant"},{"key":"10.4065\/78.5.589_bib78","doi-asserted-by":"crossref","first-page":"2458","DOI":"10.1182\/blood.V80.10.2458.2458","article-title":"Recombinant human tissue plasminogen activator for the treatment of established severe venocclusive disease of the liver after bone marrow transplantation","volume":"80","author":"Bearman","year":"1992","journal-title":"Blood"},{"key":"10.4065\/78.5.589_bib79","first-page":"635","article-title":"Successful treatment of veno-occlusive disease with recombinant tissue plasminogen activator in a patient requiring peritoneal dialysis","volume":"14","author":"Simpson","year":"1994","journal-title":"Bone Marrow Transplant"},{"key":"10.4065\/78.5.589_bib80","first-page":"1101","article-title":"Recombinant human tissue plasminogen activator for the treatment of severe hepatic veno-occlusive disease in pediatric bone marrow transplant patients","volume":"17","author":"Leahey","year":"1996","journal-title":"Bone Marrow Transplant"},{"key":"10.4065\/78.5.589_bib81","doi-asserted-by":"crossref","first-page":"1501","DOI":"10.1182\/blood.V89.5.1501","article-title":"Treatment of hepatic venocclusive disease with recombinant human tissue plasminogen activator and heparin in 42 marrow transplant patients","volume":"89","author":"Bearman","year":"1997","journal-title":"Blood"},{"key":"10.4065\/78.5.589_bib82","doi-asserted-by":"crossref","first-page":"1311","DOI":"10.1038\/sj.bmt.1702069","article-title":"Tissue plasminogen activator (tPA) as therapy for hepatotoxicity following bone marrow transplantation","volume":"24","author":"Schriber","year":"1999","journal-title":"Bone Marrow Transplant"},{"key":"10.4065\/78.5.589_bib83","first-page":"760","article-title":"Successful treatment of veno-occlusive disease of the liver with urokinase in a patient with non-Hodgkin's lymphoma","volume":"7","author":"Fogteloo","year":"1993","journal-title":"LeukemiA"},{"key":"10.4065\/78.5.589_bib84","first-page":"737","article-title":"Treatment of severe veno-occlusive disease with defibrotide: compassionate use results in response without significant toxicity in a high-risk population","volume":"92","author":"Richardson","year":"1998","journal-title":"Blood"},{"key":"10.4065\/78.5.589_bib85","doi-asserted-by":"crossref","first-page":"1122","DOI":"10.1046\/j.1365-2141.2000.02475.x","article-title":"Defibrotide for the treatment of hepatic veno-occlusive disease: results of the European compassionate-use study","volume":"111","author":"Chopra","year":"2000","journal-title":"Br J Haematol"},{"key":"10.4065\/78.5.589_bib86","doi-asserted-by":"crossref","first-page":"993","DOI":"10.1038\/sj.bmt.1702387","article-title":"N-acetylcysteine for hepatic veno-occlusive disease after allogeneic stem cell transplantation","volume":"25","author":"Ringd\u00e9n","year":"2000","journal-title":"Bone Marrow Transplant"},{"key":"10.4065\/78.5.589_bib87","doi-asserted-by":"crossref","first-page":"737","DOI":"10.1038\/sj.bmt.1702209","article-title":"Does early treatment with high-dose methylprednisolone alter the course of hepatic regimen-related toxicity?","volume":"25","author":"Khoury","year":"2000","journal-title":"Bone Marrow Transplant"},{"key":"10.4065\/78.5.589_bib88","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1007\/s00432-001-0316-z","article-title":"Hepatic veno-occlusive disease (VOD) with complete occlusion of liver venules after tandem autologous stem cell transplantation\u2014successful treatment with high-dose methylprednisolone and defibrotide","volume":"128","author":"Sayer","year":"2002","journal-title":"J Cancer Res Clin Oncol"},{"key":"10.4065\/78.5.589_bib89","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1016\/0145-2126(95)00009-D","article-title":"Successful treatment of an infant with veno-occlusive disease developed after allogeneic bone marrow transplantation by tissue plasminogen activator, heparin and prostaglandin E1","volume":"19","author":"Higashigawa","year":"1995","journal-title":"Leuk Res"},{"key":"10.4065\/78.5.589_bib90","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1007\/s002770050358","article-title":"Hepatic veno-occlusive disease in pediatric stem cell recipients: successful treatment with continuous infusion of prostaglandin E1 and low-dose heparin","volume":"76","author":"Schlegel","year":"1998","journal-title":"Ann Hematol"},{"key":"10.4065\/78.5.589_bib91","doi-asserted-by":"crossref","first-page":"829","DOI":"10.1038\/sj.bmt.1701172","article-title":"Glutamine and vitamin E in the treatment of hepatic veno-occlusive disease following high-dose chemotherapy","volume":"21","author":"Goringe","year":"1998","journal-title":"Bone Marrow Transplant"},{"key":"10.4065\/78.5.589_bib92","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1177\/011542659501000116","article-title":"Use of vitamin E and glutamine in the successful treatment of severe veno-occlusive disease following bone marrow transplantation","volume":"10","author":"Nattakom","year":"1995","journal-title":"Nutr Clin Pract"},{"key":"10.4065\/78.5.589_bib93","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1159\/000129314","article-title":"Hemodynamics and hepatic energy metabolism in canine model of acute hepatic venous occlusion with mesocaval shunt","volume":"26","author":"Terasaki","year":"1994","journal-title":"Eur Surg Res"},{"key":"10.4065\/78.5.589_bib94","doi-asserted-by":"crossref","first-page":"987","DOI":"10.1038\/sj.bmt.1702386","article-title":"Transjugular intrahepatic portosystemic shunt (TIPS) for severe veno-occlusive disease of the liver following bone marrow transplantation","volume":"25","author":"Azoulay","year":"2000","journal-title":"Bone Marrow Transplant"},{"key":"10.4065\/78.5.589_bib95","doi-asserted-by":"crossref","first-page":"588","DOI":"10.1002\/hep.510240321","article-title":"Transjugular intrahepatic portosystemic shunt for the management of severe venoocclusive disease following bone marrow transplantation","volume":"24","author":"Fried","year":"1996","journal-title":"Hepatology"},{"key":"10.4065\/78.5.589_bib96","first-page":"421","article-title":"Orthotopic liver transplantation for life-threatening venoocclusive disease of the liver after allogeneic bone marrow transplant","volume":"8","author":"Rapoport","year":"1991","journal-title":"Bone Marrow Transplant"},{"key":"10.4065\/78.5.589_bib97","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1097\/00007890-199507150-00020","article-title":"Hepatic rejection after orthotopic liver transplantation for hepatic veno-occlusive disease or graft-versus-host disease following bone marrow transplantation","volume":"60","author":"Dowlati","year":"1995","journal-title":"Transplantation"},{"key":"10.4065\/78.5.589_bib98","doi-asserted-by":"crossref","first-page":"997","DOI":"10.1038\/sj.bmt.1703267","article-title":"Charcoal hemofiltration for hepatic veno-occlusive disease after hematopoietic stem cell transplantation","volume":"28","author":"Tefferi","year":"2001","journal-title":"Bone Marrow Transplant"},{"key":"10.4065\/78.5.589_bib99","first-page":"407","article-title":"A pilot study of continuous infusion heparin for the prevention of hepatic venoocclusive disease after bone marrow transplantation","volume":"5","author":"Bearman","year":"1990","journal-title":"Bone Marrow Transplant"},{"key":"10.4065\/78.5.589_bib100","doi-asserted-by":"crossref","first-page":"2834","DOI":"10.1182\/blood.V79.11.2834.bloodjournal79112834","article-title":"Prevention of hepatic venoocclusive disease after bone marrow transplantation by continuous infusion of low-dose heparin: a prospective, randomized trial","volume":"79","author":"Attal","year":"1992","journal-title":"Blood"},{"key":"10.4065\/78.5.589_bib101","doi-asserted-by":"crossref","first-page":"1067","DOI":"10.1097\/00007890-199604150-00014","article-title":"Low molecular weight heparin for the prevention of veno-occlusive disease of the liver in bone marrow transplantation patients","volume":"61","author":"Or","year":"1996","journal-title":"Transplantation"},{"key":"10.4065\/78.5.589_bib102","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1002\/(SICI)1096-8652(199609)53:1<46::AID-AJH11>3.0.CO;2-1","article-title":"Low molecular weight heparin stimulates megakaryocytopoiesis in bone-marrow transplantation patients","volume":"53","author":"Or","year":"1996","journal-title":"Am J Hematol"},{"issue":"12, pt 1","key":"10.4065\/78.5.589_bib103","doi-asserted-by":"crossref","first-page":"975","DOI":"10.7326\/0003-4819-128-12_Part_1-199806150-00002","article-title":"Ursodiol prophylaxis against hepatic complications of allogeneic bone marrow transplantation: a randomized, double-blind, placebo-controlled trial","volume":"128","author":"Essell","year":"1998","journal-title":"Ann Intern Med"},{"key":"10.4065\/78.5.589_bib104","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1002\/(SICI)1096-8652(200005)64:1<32::AID-AJH6>3.0.CO;2-N","article-title":"The Japanese multicenter open randomized trial of ursodeoxycholic acid prophylaxis for hepatic veno-occlusive disease after stem cell transplantation","volume":"64","author":"Ohashi","year":"2000","journal-title":"Am J Hematol"},{"key":"10.4065\/78.5.589_bib105","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1038\/sj.bmt.1703342","article-title":"A randomized trial of heparin plus ursodiol vs. heparin alone to prevent hepatic veno-occlusive disease after hematopoietic stem cell transplantation","volume":"29","author":"Park","year":"2002","journal-title":"Bone Marrow Transplant"},{"key":"10.4065\/78.5.589_bib106","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1111\/j.1365-2141.1990.tb02583.x","article-title":"Use of prostaglandin E1 for prevention of liver veno-occlusive disease in leukaemic patients treated by allogeneic bone marrow transplantation","volume":"74","author":"Gluckman","year":"1990","journal-title":"Br J Haematol"},{"key":"10.4065\/78.5.589_bib107","doi-asserted-by":"crossref","first-page":"724","DOI":"10.1111\/j.1365-2141.1993.tb03152.x","article-title":"A phase I\/II study of prostaglandin E1 for the prevention of hepatic venocclusive disease after bone marrow transplantation","volume":"84","author":"Bearman","year":"1993","journal-title":"Br J Haematol"},{"key":"10.4065\/78.5.589_bib108","doi-asserted-by":"crossref","first-page":"732","DOI":"10.1182\/blood.V82.3.732.732","article-title":"Prevention of regimen-related toxicities after bone marrow transplantation by pentoxifylline: a prospective, randomized trial","volume":"82","author":"Attal","year":"1993","journal-title":"Blood"},{"key":"10.4065\/78.5.589_bib109","doi-asserted-by":"crossref","first-page":"2025","DOI":"10.1182\/blood.V82.7.2025.2025","article-title":"A randomized controlled trial of pentoxifylline for the prevention of regimen-related toxicities in patients undergoing allogeneic marrow transplantation","volume":"82","author":"Clift","year":"1993","journal-title":"Blood"},{"key":"10.4065\/78.5.589_bib110","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1038\/sj.bmt.1701321","article-title":"Parenteral glutamine protects hepatic function during bone marrow transplantation","volume":"22","author":"Brown","year":"1998","journal-title":"Bone Marrow Transplant"}],"container-title":["Mayo Clinic Proceedings"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0025619611619290?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0025619611619290?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2020,5,15]],"date-time":"2020-05-15T01:13:57Z","timestamp":1589505237000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0025619611619290"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2003,5]]},"references-count":110,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2003,5]]}},"alternative-id":["S0025619611619290"],"URL":"https:\/\/doi.org\/10.4065\/78.5.589","relation":{},"ISSN":["0025-6196"],"issn-type":[{"value":"0025-6196","type":"print"}],"subject":[],"published":{"date-parts":[[2003,5]]}}}