{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,9,13]],"date-time":"2023-09-13T20:00:20Z","timestamp":1694635220058},"reference-count":12,"publisher":"Elsevier BV","issue":"8","license":[{"start":{"date-parts":[[2006,8,1]],"date-time":"2006-08-01T00:00:00Z","timestamp":1154390400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Mayo Clinic Proceedings"],"published-print":{"date-parts":[[2006,8]]},"DOI":"10.4065\/81.8.1096","type":"journal-article","created":{"date-parts":[[2009,1,24]],"date-time":"2009-01-24T01:27:47Z","timestamp":1232760467000},"page":"1096-1099","source":"Crossref","is-referenced-by-count":0,"title":["43-Year-Old Man With Ear Pain, Confusion, and Agitation"],"prefix":"10.4065","volume":"81","author":[{"given":"Nandan S.","family":"Anavekar","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas F.","family":"Mangan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.4065\/81.8.1096_bib1","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1055\/s-2002-30100","article-title":"Biochemical and cellular mechanisms of toxic liver injury","volume":"22","author":"Kaplowitz","year":"2002","journal-title":"Semin Liver Dis"},{"key":"10.4065\/81.8.1096_bib2","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1080\/20014091111677","article-title":"Paracetamol (acetaminophen)-induced toxicity: molecular and biochemical mechanisms, analogues and protective approaches","volume":"31","author":"Bessems","year":"2001","journal-title":"Crit Rev Toxicol"},{"key":"10.4065\/81.8.1096_bib3","doi-asserted-by":"crossref","first-page":"1052","DOI":"10.1592\/phco.23.8.1052.32884","article-title":"Acetaminophen intoxication and length of treatment: how long is long enough?","volume":"23","author":"Kociancic","year":"2003","journal-title":"Pharmacotherapy"},{"key":"10.4065\/81.8.1096_bib4","series-title":"Goldfrank's Toxicologic Emergencies","first-page":"541","article-title":"Acetaminophen","author":"Smilkstein","year":"1998"},{"key":"10.4065\/81.8.1096_bib5","doi-asserted-by":"crossref","first-page":"2053","DOI":"10.1016\/0006-2952(83)90426-4","article-title":"Acetaminophen hepatotoxicity: an alternative mechanism","volume":"32","author":"Rosen","year":"1983","journal-title":"Biochem Pharmacol"},{"key":"10.4065\/81.8.1096_bib6","doi-asserted-by":"crossref","first-page":"13035","DOI":"10.1016\/S0021-9258(17)38834-8","article-title":"The toxicity of acetaminophen and N-acetyl-p-benzoquinone imine in isolated hepatocytes is associated with thiol depletion and increased cytosolic Ca2+","volume":"260","author":"Moore","year":"1985","journal-title":"J Biol Chem"},{"key":"10.4065\/81.8.1096_bib7","doi-asserted-by":"crossref","first-page":"767","DOI":"10.1002\/hep.1840220312","article-title":"Acetaminophen (Paracetamol) hepatotoxicity with regular intake of alcohol: analysis of instances of therapeutic misadventure","volume":"22","author":"Zimmerman","year":"1995","journal-title":"Hepatology"},{"key":"10.4065\/81.8.1096_bib8","doi-asserted-by":"crossref","first-page":"2247","DOI":"10.1001\/archinte.161.18.2247","article-title":"Effect of maximal daily doses of acetaminophen on the liver of alcoholic patients: a randomized, double blind, placebo controlled trial","volume":"161","author":"Kuffner","year":"2001","journal-title":"Arch Intern Med"},{"key":"10.4065\/81.8.1096_bib9","doi-asserted-by":"crossref","first-page":"410","DOI":"10.3122\/15572625-11-5-410","article-title":"Acute renal failure in an alcoholic patient taking therapeutic doses of acetaminophen","volume":"11","author":"Maze","year":"1998","journal-title":"J Am Board Fam Pract"},{"issue":"1, suppl 1","key":"10.4065\/81.8.1096_bib10","doi-asserted-by":"crossref","first-page":"S3","DOI":"10.1016\/S0272-6386(96)90561-2","article-title":"Acetaminophen: acute and chronic effects on renal function","volume":"28","author":"Blantz","year":"1996","journal-title":"Am J Kidney Dis"},{"key":"10.4065\/81.8.1096_bib11","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1016\/0016-5085(89)90081-4","article-title":"Early indicators of prognosis in fulminant hepatic failure","volume":"97","author":"O'Grady","year":"1989","journal-title":"Gastroenterology"},{"key":"10.4065\/81.8.1096_bib12","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1097\/00003246-200301000-00048","article-title":"Fulminant hepatic failure secondary to acetaminophen poisoning: a systematic review and meta-analysis of prognostic criteria determining the need for liver transplantation","volume":"31","author":"Bailey","year":"2003","journal-title":"Crit Care Med"}],"container-title":["Mayo Clinic Proceedings"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0025619611612111?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0025619611612111?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2021,9,30]],"date-time":"2021-09-30T14:02:43Z","timestamp":1633010563000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0025619611612111"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,8]]},"references-count":12,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2006,8]]}},"alternative-id":["S0025619611612111"],"URL":"https:\/\/doi.org\/10.4065\/81.8.1096","relation":{},"ISSN":["0025-6196"],"issn-type":[{"value":"0025-6196","type":"print"}],"subject":[],"published":{"date-parts":[[2006,8]]}}}