{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T10:47:39Z","timestamp":1790938059525,"version":"4.1.0"},"reference-count":69,"publisher":"XMLink","issue":"7","license":[{"start":{"date-parts":[[2019,1,1]],"date-time":"2019-01-01T00:00:00Z","timestamp":1546300800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0"}],"content-domain":{"domain":["synapse.koreamed.org"],"crossmark-restriction":false},"short-container-title":["Korean Circ J"],"DOI":"10.4070\/kcj.2019.0161","type":"journal-article","created":{"date-parts":[[2019,6,21]],"date-time":"2019-06-21T02:39:15Z","timestamp":1561084755000},"page":"568","update-policy":"https:\/\/doi.org\/10.4070\/crossmark_policy","source":"Crossref","is-referenced-by-count":55,"title":["Left Ventricular Assist Devices (LVADS): History, Clinical Application and Complications"],"prefix":"10.4070","volume":"49","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1149-4344","authenticated-orcid":false,"given":"Howard J.","family":"Eisen","sequence":"first","affiliation":[{"name":"Heart and Vascular Institute, Pennsylvania State University, Milton S. Hershey Medical Center, Hershey, PA, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"18617","published-online":{"date-parts":[[2019]]},"reference":[{"key":"10.4070\/kcj.2019.0161_ref1","unstructured":"Centers for Disease Control and Prevention. Heart failure fact sheet [Internet]. Atlanta. Centers for Disease Control and Prevention. 2019. cited 2019 April 30. Available from https:\/\/www.cdc.gov\/dhdsp\/data_statistics\/fact_sheets\/fs_heart_failure.htm"},{"key":"10.4070\/kcj.2019.0161_ref2","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1016\/j.pcad.2011.06.002","volume":"54","author":"Patel","year":"2011","journal-title":"Prog Cardiovasc Dis"},{"key":"10.4070\/kcj.2019.0161_ref3","doi-asserted-by":"crossref","first-page":"1304","DOI":"10.1161\/CIRCULATIONAHA.111.060830","volume":"125","author":"Stewart","year":"2012","journal-title":"Circulation"},{"key":"10.4070\/kcj.2019.0161_ref4","first-page":"171","volume":"37","author":"Gibbon","year":"1954","journal-title":"Minn Med"},{"key":"10.4070\/kcj.2019.0161_ref5","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1053\/stcs.2000.18455","volume":"12","author":"Frazier","year":"2000","journal-title":"Semin Thorac Cardiovasc Surg"},{"key":"10.4070\/kcj.2019.0161_ref6","volume-title":"The artificial heart: prototypes, policies, and patients","author":"Hogness","year":"1991"},{"key":"10.4070\/kcj.2019.0161_ref7","doi-asserted-by":"crossref","first-page":"S1","DOI":"10.1016\/j.hfc.2013.08.003","volume":"10","author":"Stewart","year":"2014","journal-title":"Heart Fail Clin"},{"key":"10.4070\/kcj.2019.0161_ref8","first-page":"11","volume":"2018","author":"Cooper","year":"2018","journal-title":"Glob Cardiol Sci Pract"},{"key":"10.4070\/kcj.2019.0161_ref9","doi-asserted-by":"crossref","first-page":"1435","DOI":"10.1056\/NEJMoa012175","volume":"345","author":"Rose","year":"2001","journal-title":"N Engl J Med"},{"key":"10.4070\/kcj.2019.0161_ref10","doi-asserted-by":"crossref","first-page":"885","DOI":"10.1056\/NEJMoa067758","volume":"357","author":"Miller","year":"2007","journal-title":"N Engl J Med"},{"key":"10.4070\/kcj.2019.0161_ref11","doi-asserted-by":"crossref","first-page":"400","DOI":"10.1093\/ejcts\/ezt589","volume":"45","author":"Lok","year":"2014","journal-title":"Eur J Cardiothorac Surg"},{"key":"10.4070\/kcj.2019.0161_ref12","doi-asserted-by":"crossref","first-page":"2241","DOI":"10.1056\/NEJMoa0909938","volume":"361","author":"Slaughter","year":"2009","journal-title":"N Engl J Med"},{"key":"10.4070\/kcj.2019.0161_ref13","doi-asserted-by":"crossref","first-page":"S9","DOI":"10.1016\/j.healun.2015.01.012","volume":"34","author":"Pagani","year":"2015","journal-title":"J Heart Lung Transplant"},{"key":"10.4070\/kcj.2019.0161_ref14","first-page":"e240","volume":"128","author":"WRITING COMMITTEE MEMBERS","year":"2013","journal-title":"Circulation"},{"key":"10.4070\/kcj.2019.0161_ref15","doi-asserted-by":"crossref","first-page":"1209","DOI":"10.1016\/j.jacc.2012.08.1029","volume":"61","author":"Miller","year":"2013","journal-title":"J Am Coll Cardiol"},{"key":"10.4070\/kcj.2019.0161_ref16","doi-asserted-by":"crossref","first-page":"1065","DOI":"10.1016\/j.healun.2008.07.021","volume":"27","author":"Kirklin","year":"2008","journal-title":"J Heart Lung Transplant"},{"key":"10.4070\/kcj.2019.0161_ref17","doi-asserted-by":"crossref","first-page":"3020","DOI":"10.1111\/ajt.14403","volume":"17","author":"Cai","year":"2017","journal-title":"Am J Transplant"},{"key":"10.4070\/kcj.2019.0161_ref18","doi-asserted-by":"crossref","first-page":"1873","DOI":"10.1056\/NEJMoa053063","volume":"355","author":"Birks","year":"2006","journal-title":"N Engl J Med"},{"key":"10.4070\/kcj.2019.0161_ref19","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1161\/CIRCULATIONAHA.111.040261","volume":"126","author":"Drakos","year":"2012","journal-title":"Circulation"},{"key":"10.4070\/kcj.2019.0161_ref20","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1016\/j.healun.2016.01.001","volume":"35","author":"Drakos","year":"2016","journal-title":"J Heart Lung Transplant"},{"key":"10.4070\/kcj.2019.0161_ref21","doi-asserted-by":"crossref","first-page":"1495","DOI":"10.1016\/j.healun.2015.10.003","volume":"34","author":"Kirklin","year":"2015","journal-title":"J Heart Lung Transplant"},{"key":"10.4070\/kcj.2019.0161_ref22","doi-asserted-by":"crossref","first-page":"722","DOI":"10.1016\/j.healun.2016.01.014","volume":"35","author":"Ambardekar","year":"2016","journal-title":"J Heart Lung Transplant"},{"key":"10.4070\/kcj.2019.0161_ref23","doi-asserted-by":"crossref","first-page":"1747","DOI":"10.1016\/j.jacc.2015.07.075","volume":"66","author":"Estep","year":"2015","journal-title":"J Am Coll Cardiol"},{"key":"10.4070\/kcj.2019.0161_ref24","doi-asserted-by":"crossref","first-page":"518","DOI":"10.1016\/j.jchf.2017.02.016","volume":"5","author":"Starling","year":"2017","journal-title":"JACC Heart Fail"},{"key":"10.4070\/kcj.2019.0161_ref25","first-page":"379","volume":"7","author":"Hayek","year":"2014"},{"key":"10.4070\/kcj.2019.0161_ref26","doi-asserted-by":"crossref","first-page":"478","DOI":"10.1253\/circj.CJ-15-0093","volume":"79","author":"Holman","year":"2015","journal-title":"Circ J"},{"key":"10.4070\/kcj.2019.0161_ref27","doi-asserted-by":"crossref","first-page":"926","DOI":"10.1002\/ejhf.733","volume":"19","author":"Bellavia","year":"2017","journal-title":"Eur J Heart Fail"},{"key":"10.4070\/kcj.2019.0161_ref28","doi-asserted-by":"crossref","first-page":"701","DOI":"10.1016\/j.healun.2017.03.014","volume":"36","author":"Houston","year":"2017","journal-title":"J Heart Lung Transplant"},{"key":"10.4070\/kcj.2019.0161_ref29","first-page":"300","volume":"108","author":"Aissaoui","year":"2015"},{"key":"10.4070\/kcj.2019.0161_ref30","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1111\/j.1751-7133.2011.00236.x","volume":"17","author":"Khazanie","year":"2011","journal-title":"Congest Heart Fail"},{"key":"10.4070\/kcj.2019.0161_ref31","doi-asserted-by":"crossref","first-page":"1534","DOI":"10.1016\/j.athoracsur.2012.02.035","volume":"93","author":"Aggarwal","year":"2012","journal-title":"Ann Thorac Surg"},{"key":"10.4070\/kcj.2019.0161_ref32","doi-asserted-by":"crossref","first-page":"1859","DOI":"10.1007\/s10620-015-3538-7","volume":"60","author":"Marsano","year":"2015","journal-title":"Dig Dis Sci"},{"key":"10.4070\/kcj.2019.0161_ref33","doi-asserted-by":"crossref","first-page":"S-558","DOI":"10.1016\/S0016-5085(14)62021-7","volume":"146","author":"Draper","year":"2014","journal-title":"Gastroenterology"},{"key":"10.4070\/kcj.2019.0161_ref34","doi-asserted-by":"crossref","first-page":"1020","DOI":"10.1016\/j.transproceed.2013.02.072","volume":"45","author":"Balcioglu","year":"2013","journal-title":"Transplant Proc"},{"key":"10.4070\/kcj.2019.0161_ref35","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1016\/j.ccl.2018.06.006","volume":"36","author":"Kim","year":"2018","journal-title":"Cardiol Clin"},{"key":"10.4070\/kcj.2019.0161_ref36","doi-asserted-by":"crossref","first-page":"12171","DOI":"10.1074\/jbc.M305146200","volume":"279","author":"Pichiule","year":"2004","journal-title":"J Biol Chem"},{"key":"10.4070\/kcj.2019.0161_ref37","doi-asserted-by":"crossref","first-page":"664","DOI":"10.1161\/01.RES.0000093984.48643.D7","volume":"93","author":"Yamakawa","year":"2003","journal-title":"Circ Res"},{"key":"10.4070\/kcj.2019.0161_ref38","doi-asserted-by":"crossref","first-page":"703","DOI":"10.1111\/j.1525-1594.2010.01084.x","volume":"34","author":"Hayes","year":"2010","journal-title":"Artif Organs"},{"key":"10.4070\/kcj.2019.0161_ref39","doi-asserted-by":"crossref","first-page":"636","DOI":"10.5301\/ijao.5000620","volume":"40","author":"Seng","year":"2017","journal-title":"Int J Artif Organs"},{"key":"10.4070\/kcj.2019.0161_ref40","doi-asserted-by":"crossref","first-page":"e004899","DOI":"10.1161\/CIRCHEARTFAILURE.118.004899","volume":"11","author":"Vukelic","year":"2018","journal-title":"Circ Heart Fail"},{"key":"10.4070\/kcj.2019.0161_ref41","doi-asserted-by":"crossref","first-page":"1207","DOI":"10.1016\/j.jacc.2010.05.016","volume":"56","author":"Uriel","year":"2010","journal-title":"J Am Coll Cardiol"},{"key":"10.4070\/kcj.2019.0161_ref42","doi-asserted-by":"crossref","first-page":"1003","DOI":"10.1161\/CIRCHEARTFAILURE.114.001391","volume":"7","author":"McIlvennan","year":"2014","journal-title":"Circ Heart Fail"},{"key":"10.4070\/kcj.2019.0161_ref43","doi-asserted-by":"crossref","first-page":"792","DOI":"10.4330\/wjc.v7.i11.792","volume":"7","author":"Tsiouris","year":"2015","journal-title":"World J Cardiol"},{"key":"10.4070\/kcj.2019.0161_ref44","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1016\/j.athoracsur.2015.02.094","volume":"100","author":"Harvey","year":"2015","journal-title":"Ann Thorac Surg"},{"key":"10.4070\/kcj.2019.0161_ref45","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1016\/j.jjcc.2014.06.007","volume":"65","author":"Kimura","year":"2015","journal-title":"J Cardiol"},{"key":"10.4070\/kcj.2019.0161_ref46","unstructured":"INTERMACS. Initial analyses of suspected pump thrombosis [Internet]. Birmingham. University of Alabama at Birmingham (UAB) School of Medicine. 2013. cited 2016 February 1. Available from  https:\/\/www.uab.edu\/medicine\/intermacs\/images\/INTERMACS_PI_and_Website_Notice_9-6-2013_2.pdf"},{"key":"10.4070\/kcj.2019.0161_ref47","doi-asserted-by":"crossref","first-page":"1463","DOI":"10.1056\/NEJMc1401768","volume":"370","author":"Schmitto","year":"2014","journal-title":"N Engl J Med"},{"key":"10.4070\/kcj.2019.0161_ref48","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.healun.2016.10.001","volume":"36","author":"Maltais","year":"2017","journal-title":"J Heart Lung Transplant"},{"key":"10.4070\/kcj.2019.0161_ref49","doi-asserted-by":"crossref","first-page":"775","DOI":"10.1111\/jocs.12607","volume":"30","author":"Klodell","year":"2015","journal-title":"J Card Surg"},{"key":"10.4070\/kcj.2019.0161_ref50","doi-asserted-by":"crossref","first-page":"472","DOI":"10.1007\/s11908-013-0366-9","volume":"15","author":"Martin","year":"2013","journal-title":"Curr Infect Dis Rep"},{"key":"10.4070\/kcj.2019.0161_ref51","doi-asserted-by":"crossref","first-page":"360","DOI":"10.1097\/HCO.0b013e32835fb7dc","volume":"28","author":"Pedrotty","year":"2013","journal-title":"Curr Opin Cardiol"},{"key":"10.4070\/kcj.2019.0161_ref52","first-page":"2125","volume":"7","author":"Bennett","year":"2015","journal-title":"J Thorac Dis"},{"key":"10.4070\/kcj.2019.0161_ref53","doi-asserted-by":"crossref","first-page":"1764","DOI":"10.1016\/j.jacc.2012.07.052","volume":"60","author":"Uriel","year":"2012","journal-title":"J Am Coll Cardiol"},{"key":"10.4070\/kcj.2019.0161_ref54","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1016\/j.ccl.2018.06.013","volume":"36","author":"Narang","year":"2018","journal-title":"Cardiol Clin"},{"key":"10.4070\/kcj.2019.0161_ref55","doi-asserted-by":"crossref","first-page":"e010232","DOI":"10.1161\/JAHA.118.010232","volume":"8","author":"Rosenbaum","year":"2019","journal-title":"J Am Heart Assoc"},{"key":"10.4070\/kcj.2019.0161_ref56","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1016\/j.jchf.2015.10.001","volume":"4","author":"Uriel","year":"2016","journal-title":"JACC Heart Fail"},{"key":"10.4070\/kcj.2019.0161_ref57","doi-asserted-by":"crossref","first-page":"440","DOI":"10.1056\/NEJMoa1610426","volume":"376","author":"Mehra","year":"2017","journal-title":"N Engl J Med"},{"key":"10.4070\/kcj.2019.0161_ref58","doi-asserted-by":"crossref","first-page":"1386","DOI":"10.1056\/NEJMoa1800866","volume":"378","author":"Mehra","year":"2018","journal-title":"N Engl J Med"},{"key":"10.4070\/kcj.2019.0161_ref59","doi-asserted-by":"crossref","first-page":"1618","DOI":"10.1056\/NEJMoa1900486","volume":"380","author":"Mehra","year":"2019","journal-title":"N Engl J Med"},{"key":"10.4070\/kcj.2019.0161_ref60","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1097\/00002480-200009000-00014","volume":"46","author":"Dowling","year":"2000","journal-title":"ASAIO J"},{"key":"10.4070\/kcj.2019.0161_ref61","doi-asserted-by":"crossref","first-page":"e31","DOI":"10.1097\/01.mat.0000249019.38139.4b","volume":"52","author":"Mehta","year":"2006","journal-title":"ASAIO J"},{"key":"10.4070\/kcj.2019.0161_ref62","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1016\/j.healun.2006.12.007","volume":"26","author":"Pae","year":"2007","journal-title":"J Heart Lung Transplant"},{"key":"10.4070\/kcj.2019.0161_ref63","volume-title":"CEO Leviticus Cardio, Personal communication","author":"Michael Zilbershlag"},{"key":"10.4070\/kcj.2019.0161_ref64","doi-asserted-by":"crossref","first-page":"1027","DOI":"10.1016\/j.healun.2017.07.024","volume":"36","author":"Kransdorf","year":"2017","journal-title":"J Heart Lung Transplant"},{"key":"10.4070\/kcj.2019.0161_ref65","doi-asserted-by":"crossref","first-page":"1009","DOI":"10.1016\/j.healun.2014.08.004","volume":"33","author":"Yusen","year":"2014","journal-title":"J Heart Lung Transplant"},{"key":"10.4070\/kcj.2019.0161_ref66","doi-asserted-by":"crossref","first-page":"1052","DOI":"10.1016\/j.healun.2012.08.002","volume":"31","author":"Stehlik","year":"2012","journal-title":"J Heart Lung Transplant"},{"key":"10.4070\/kcj.2019.0161_ref67","doi-asserted-by":"crossref","first-page":"847","DOI":"10.1056\/NEJMoa022171","volume":"349","author":"Eisen","year":"2003","journal-title":"N Engl J Med"},{"key":"10.4070\/kcj.2019.0161_ref68","doi-asserted-by":"crossref","first-page":"651","DOI":"10.1016\/j.jacc.2017.12.033","volume":"71","author":"Eisen","year":"2018","journal-title":"J Am Coll Cardiol"},{"key":"10.4070\/kcj.2019.0161_ref69","doi-asserted-by":"crossref","first-page":"883","DOI":"10.1097\/01.TP.0000184006.43152.8D","volume":"80","author":"Kauffman","year":"2005","journal-title":"Transplantation"}],"container-title":["Korean Circulation Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/synapse.koreamed.org\/pdf\/10.4070\/kcj.2019.0161","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/synapse.koreamed.org\/DOIx.php?id=10.4070\/kcj.2019.0161","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/e-kcj.org\/DOIx.php?id=10.4070\/kcj.2019.0161","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,5,15]],"date-time":"2020-05-15T07:19:43Z","timestamp":1589527183000},"score":1,"resource":{"primary":{"URL":"https:\/\/e-kcj.org\/DOIx.php?id=10.4070\/kcj.2019.0161"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019]]},"references-count":69,"journal-issue":{"issue":"7","published-online":{"date-parts":[[2019]]}},"URL":"https:\/\/doi.org\/10.4070\/kcj.2019.0161","relation":{},"ISSN":["1738-5520","1738-5555"],"issn-type":[{"value":"1738-5520","type":"print"},{"value":"1738-5555","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019]]},"assertion":[{"value":"https:\/\/synapse.koreamed.org\/DOIx.php?id=10.4070\/kcj.2019.0161","URL":"https:\/\/synapse.koreamed.org\/DOIx.php?id=10.4070\/kcj.2019.0161","name":"synapse","label":"Synapse","group":{"name":"multiple_resolution","label":"Full text available at:"}},{"value":"https:\/\/e-kcj.org\/DOIx.php?id=10.4070\/kcj.2019.0161","URL":"https:\/\/e-kcj.org\/DOIx.php?id=10.4070\/kcj.2019.0161","name":"the_journal","label":"the Journal","group":{"name":"multiple_resolution","label":"Full text available at:"}},{"value":"2019-05-30","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-06-03","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-06-20","name":"published_online","label":"Published online","group":{"name":"publication_history","label":"Publication History"}},{"value":"Copyright \u00a9 2019. The Korean Society of Cardiology","name":"copyright","label":"Copyright","group":{"name":"Copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (https:\/\/creativecommons.org\/licenses\/by-nc\/4.0) which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original work is properly cited.","name":"license","label":"License","explanation":{"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0"},"group":{"name":"Copyright_and_licensing","label":"Copyright and Licensing"}}]}}