{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,20]],"date-time":"2026-05-20T02:18:15Z","timestamp":1779243495686,"version":"3.51.4"},"reference-count":28,"publisher":"Korean College of Rheumatology","issue":"1","license":[{"start":{"date-parts":[[2025,7,22]],"date-time":"2025-07-22T00:00:00Z","timestamp":1753142400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0"}],"funder":[{"DOI":"10.13039\/501100002386","name":"Cairo University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002386","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["www.jrd.or.kr"],"crossmark-restriction":true},"short-container-title":["J Rheum Dis"],"published-print":{"date-parts":[[2026,1,1]]},"DOI":"10.4078\/jrd.2025.0074","type":"journal-article","created":{"date-parts":[[2025,7,22]],"date-time":"2025-07-22T04:59:12Z","timestamp":1753160352000},"page":"55-64","update-policy":"https:\/\/doi.org\/10.4078\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Genetic and epigenetic insights into systemic lupus erythematosus: linking long non-coding RNA growth arrest-specific transcript 5 and interferon signature"],"prefix":"10.4078","volume":"33","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6013-2038","authenticated-orcid":false,"given":"Gehad Gamal","family":"Maghraby","sequence":"first","affiliation":[{"name":"Rheumatology and Clinical Immunology Unit, Department of Internal Medicine, Cairo University, Cairo, Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9859-2352","authenticated-orcid":false,"given":"Manal Abdel-Moneim","family":"El-Menyawi","sequence":"additional","affiliation":[{"name":"Rheumatology and Clinical Immunology Unit, Department of Internal Medicine, Cairo University, Cairo, Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-9300-8221","authenticated-orcid":false,"given":"Hanan A. Abdel","family":"Rehiem","sequence":"additional","affiliation":[{"name":"Rheumatology and Clinical Immunology Unit, Department of Internal Medicine, Cairo University, Cairo, Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3031-3599","authenticated-orcid":false,"given":"Olfat Gamil","family":"Shaker","sequence":"additional","affiliation":[{"name":"Medical Biochemistry and Molecular Biology, Cairo University, Cairo, Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9371-7446","authenticated-orcid":false,"given":"Mina M.","family":"Habib","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Faculty of Medicine Kasr Alainy, Cairo University, Cairo, Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4002-1485","authenticated-orcid":false,"given":"Rasmia","family":"Elgohary","sequence":"additional","affiliation":[{"name":"Rheumatology and Clinical Immunology Unit, Department of Internal Medicine, Cairo University, Cairo, Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2544","published-online":{"date-parts":[[2025,7,22]]},"reference":[{"key":"ref1","unstructured":"Maidhof W, Hilas O. Lupus: an overview of the disease and management options. P T 2012;37:240-9."},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1002\/art.20254"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2249.1999.00772.x"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.171.6.3296"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1016\/j.trsl.2021.07.006"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1002\/wrna.1376"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.18632\/oncotarget.15569"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.3390\/biom9060206"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.3892\/etm.2017.5429"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0098561"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0185406"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.3892\/mmr.2019.9883"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1002\/cam4.1524"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1002\/art.34473"},{"key":"ref15","unstructured":"Gladman DD, Iba\u00f1ez D, Urowitz MB. Systemic lupus erythematosus disease activity index 2000. J Rheumatol 2002;29:288-91."},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1002\/art.1780390303"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1002\/art.22044"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1186\/s13075-021-02414-0"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1186\/s13075-019-2034-4"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1136\/lupus-2014-000080"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1177\/0961203309105529"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1136\/ard.2008.093146"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1016\/j.prp.2022.153856"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.1186\/s12920-018-0468-1"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.1038\/s42003-019-0382-x"},{"key":"ref26","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/kem112"},{"key":"ref27","doi-asserted-by":"publisher","DOI":"10.3899\/jrheum.210391"},{"key":"ref28","doi-asserted-by":"publisher","DOI":"10.1002\/art.21031"}],"container-title":["Journal of Rheumatic Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pdf.medrang.co.kr\/JRD\/2026\/033\/JRD033-01-55.pdf","content-type":"unspecified","content-version":"tdm","intended-application":"text-mining"},{"URL":"https:\/\/pdf.medrang.co.kr\/JRD\/2026\/033\/JRD033-01-55.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,24]],"date-time":"2025-12-24T05:54:23Z","timestamp":1766555663000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.jrd.or.kr\/journal\/view.html?doi=10.4078\/jrd.2025.0074"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,7,22]]},"references-count":28,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,1,1]]}},"alternative-id":["10.4078\/jrd.2025.0074"],"URL":"https:\/\/doi.org\/10.4078\/jrd.2025.0074","relation":{},"ISSN":["2093-940X","2233-4718"],"issn-type":[{"value":"2093-940X","type":"print"},{"value":"2233-4718","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,7,22]]},"assertion":[{"value":"http:\/\/www.jrd.or.kr\/journal\/view.html?doi=10.4078\/jrd.2025.0074","URL":"http:\/\/www.jrd.or.kr\/journal\/view.html?doi=10.4078\/jrd.2025.0074","name":"the_journal","label":"J Rheum Dis","group":{"name":"multiple_resolution","label":"Full text available at:"}},{"value":"2025-05-19","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-06-24","order":1,"name":"revised","label":"Revised","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-06-26","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-07-22","order":3,"name":"published","label":"Online First","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-01-01","order":4,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}},{"value":"\u00a9 2026 The Korean College of Rheumatology","name":"copyright","label":"Copyright","group":{"name":"Copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http:\/\/creativecommons.org\/licenses\/by-nc\/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.","name":"license","label":"License","explanation":{"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0"},"group":{"name":"Copyright_and_licensing","label":"Copyright and Licensing"}}]}}