{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,2]],"date-time":"2026-06-02T01:36:43Z","timestamp":1780364203864,"version":"3.54.1"},"reference-count":23,"publisher":"PAGEPress Publications","issue":"1","license":[{"start":{"date-parts":[[2022,3,29]],"date-time":"2022-03-29T00:00:00Z","timestamp":1648512000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arch Ital Urol Androl"],"abstract":"<jats:p>Objective: Plaque incision and grafting is indicated for patients with Peyronie\u2019s Disease [PD] and severe curvature, complex deformities or for patients with significant penile shortening. To date, no graft studied has been considered ideal. The aim of this study is to conduct a descriptive analysis about functional results with the use of a bioabsorbable graft for PD treatment. Materials and methods: A single-center, retrospective evaluation of a cohort of patients who were treated by plaque incision and grafting with a polyglycolic acid polymer graft (Gore\u00ae Bio-A\u00ae) between 2018 and 2021 was conducted. Correction of penile curvature was the main outcome. Loss of penile sensitivity, de novo erectile dysfunction and any other adverse event were the secondary endpoints. Results: 14 patients were included in this study (mean age 59.5 \u00b1 7.2 years). The median follow-up time was 12 months (range 3-12). The curvature correction rate was 78.5%. Glans hypoesthesia was present in one of 14 patients (7.1%) and refractory erectile dysfunction was reported in 64.2%. None of the patients presented any major adverse event based on Clavien-Dindo classification. Conclusions: Curvature correction and changes in penile sensitivity rates were similar to those found in the literature. No major surgical complications, such as graft rejection, infection, and extrusion, occurred in this sample. Although a population with a higher prevalence of erectile dysfunction was included in this sample, higher rates of refractory erectile dysfunction were observed and these findings should be confirmed in further studies.<\/jats:p>","DOI":"10.4081\/aiua.2022.1.87","type":"journal-article","created":{"date-parts":[[2022,3,29]],"date-time":"2022-03-29T13:58:11Z","timestamp":1648562291000},"page":"87-90","source":"Crossref","is-referenced-by-count":3,"title":["The use of a polyglycolic acid polymer graft in Peyronie\u2019s disease - preliminary outcomes"],"prefix":"10.4081","volume":"94","author":[{"given":"Pedro Caetano","family":"Edler Zandon\u00e1","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nivio Pascoal","family":"Teixeira","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Henrique Eduardo","family":"Oliveira","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jorge Hamilton","family":"Soares Garcia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2549","published-online":{"date-parts":[[2022,3,29]]},"reference":[{"key":"49908","doi-asserted-by":"crossref","unstructured":"Devine Jr CJ, Somers KD, Jordan SG, Schlossberg, SM. Proposal: trauma as the cause of the Peyronie\u2019s lesion. J Urol. 1997; 157: 285.","DOI":"10.1016\/S0022-5347(01)65361-8"},{"key":"49909","doi-asserted-by":"crossref","unstructured":"Kadioglu A, Tefekli A, Erol B, et al. A retrospective review of 307 men with Peyronie\u2019s disease. J Urol. 2002; 168:1075.","DOI":"10.1016\/S0022-5347(05)64578-8"},{"key":"49910","doi-asserted-by":"crossref","unstructured":"Rhoden EL, Riedner CE, Fuchs SC, et al. A cross-sectional study for the analysis of clinical, sexual and laboratory conditions associated to Peyronie\u2019s disease. J Sex Med. 2010; 7:1529.","DOI":"10.1111\/j.1743-6109.2009.01584.x"},{"key":"49911","doi-asserted-by":"crossref","unstructured":"Ralph D, Gonzalez-Cadavid N, Mirone V, et al. The management of Peyronie\u2019s disease: evidence-based 2010 guidelines. J Sex Med, 2010. 7:2359.","DOI":"10.1111\/j.1743-6109.2010.01850.x"},{"key":"49912","doi-asserted-by":"crossref","unstructured":"Chung E, Ralph D, Kagioglu A, et al. Evidence-based management guidelines on Peyronie\u2019s disease. J Sex Med. 2016; 13:905.","DOI":"10.1016\/j.jsxm.2016.04.062"},{"key":"49913","doi-asserted-by":"crossref","unstructured":"Mulhall J, Anderson M, Parker M. A surgical algorithm for men with combined Peyronie\u2019s disease and erectile dysfunction: functional and satisfaction outcomes. J Sex Med. 2005; 2:132.","DOI":"10.1111\/j.1743-6109.2005.20113.x"},{"key":"49914","doi-asserted-by":"crossref","unstructured":"Zaid UB, Alwaal A, Zhang X, Lue TF. Surgical management of Peyronie\u2019s disease. Current Urol Rep. 2014; 15:446.","DOI":"10.1007\/s11934-014-0446-x"},{"key":"49915","doi-asserted-by":"crossref","unstructured":"Garcia-Gomez B, Ralph D, Levine L, et al. Grafts for Peyronie's disease: a comprehensive review. Andrology. 2018; 6:117-126.","DOI":"10.1111\/andr.12421"},{"key":"49916","doi-asserted-by":"crossref","unstructured":"Carson CC, Levine LA. Outcomes of surgical treatment of Peyronie's disease. 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Long-term results of the surgical treatment of Peyronie\u2019s disease with Egydio\u2019s technique: a European multicentre study. Asian J Androl. 2011; 13:842.","DOI":"10.1038\/aja.2011.42"},{"key":"49925","doi-asserted-by":"crossref","unstructured":"Terrier JE, Tal R, Nelson CJ, Mulhall JP. Penile Sensory Changes After Plaque Incision and Grafting Surgery for Peyronie\u2019s Disease. J Sex Med. 2018; 15:1491.","DOI":"10.1016\/j.jsxm.2018.07.020"},{"key":"49926","doi-asserted-by":"crossref","unstructured":"Fabiani A, Servi L, Fioretti F, et al. Buccal mucosa is a promising graft in Peyronie\u2019s disease surgery. Our experience and a brief literature review on autologous grafting materials. Arch Ital Urol Androl. 2016; 88:115-21.","DOI":"10.4081\/aiua.2016.2.115"},{"key":"49927","doi-asserted-by":"crossref","unstructured":"Fabiani A, Fioretti F, Pavia MP, et al. Buccal mucosa graft in surgical management of Peyronie's disease: Ultrasound features and clinical outcomes. 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