{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T18:09:26Z","timestamp":1789495766419,"version":"build-2803163510"},"reference-count":22,"publisher":"PAGEPress Publications","issue":"2","license":[{"start":{"date-parts":[[2022,6,29]],"date-time":"2022-06-29T00:00:00Z","timestamp":1656460800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arch Ital Urol Androl"],"abstract":"<jats:p>Introduction: Novel laser technologies have been developed for the minimally invasive surgical management of benign prostatic hyperplasia (BPH). The objective of this study was to assess the safety and efficacy of MOSESTM technology versus the thulium fiber laser (TFL) in patients with BPH undergoing transurethral enucleation of the prostate. Methods: We conducted a retrospective review of prospectively collected data of eighty-two patients who underwent transurethral enucleation of the prostate using MOSESTM or TFL technologies from August 2020 to September 2021. Preoperative and intraoperative parameters, in addition to postoperative outcomes, were collected and analyzed. Results: Twenty patients underwent transurethral enucleation of the prostate with TFL, while 62 had MOSESTM HoLEP. No statistically significant difference in preoperative characteristics was observed between the groups. Patients in the TFL group had longer median enucleation, hemostasis, and morcellation times (p &lt; 0.001) than those in the MOSESTM cohort. The longer morcellation time of TFL is mostly related to less visibility. The postoperative outcomes IPSS, QoL, Qmax, and post void residual (PVR), were comparable between the groups at 1, 3 and 6 months. The incidence of urge urinary incontinence (p = 0.79), stress urinary incontinence (p = 0.97), and hospital readmission rates (p = 0.1) were comparable between the two groups. Conclusions: A satisfactory safety and efficacy profile with comparable postoperative outcomes was demonstrated for both techniques; though, MOSESTM technology was superior to TFL in terms of shorter overall operative time.<\/jats:p>","DOI":"10.4081\/aiua.2022.2.180","type":"journal-article","created":{"date-parts":[[2022,6,30]],"date-time":"2022-06-30T03:36:12Z","timestamp":1656560172000},"page":"180-185","source":"Crossref","is-referenced-by-count":17,"title":["Comparative analysis of MOSES&lt;sup&gt;TM&lt;\/sup&gt; technology versus novel thulium fiber laser (TFL) for transurethral enucleation of the prostate: A single-institutional study"],"prefix":"10.4081","volume":"94","author":[{"given":"Hazem","family":"Elmansy","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amr","family":"Hodhod","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahmed","family":"Elshafei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasser A.","family":"Noureldin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vahid","family":"Mehrnoush","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahmed S.","family":"Zakaria","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruba Abdul","family":"Hadi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Moustafa","family":"Fathy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Loay","family":"Abbas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahmed","family":"Kotb","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Walid","family":"Shahrour","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2549","published-online":{"date-parts":[[2022,6,29]]},"reference":[{"key":"53764","doi-asserted-by":"crossref","unstructured":"Herrmann TR. Enucleation is enucleation is enucleation is enucleation. World J Urol 2016; 34(10): 1353-5.","DOI":"10.1007\/s00345-016-1922-3"},{"key":"53765","doi-asserted-by":"crossref","unstructured":"Kuntz RM, Ahyai S, Lehrich K, Fayad A. Transurethral holmium laser enucleation of the prostate versus transurethral electrocautery resection of the prostate: a randomized prospective trial in 200 patients. J Urol 2004; 172(3): 1012-6.","DOI":"10.1097\/01.ju.0000136218.11998.9e"},{"key":"53766","doi-asserted-by":"crossref","unstructured":"Li S, Zeng XT, Ruan XL, Weng H, Liu TZ, Wang X, et al. Holmium laser enucleation versus transurethral resection in patients with benign prostate hyperplasia: an updated systematic review with meta-analysis and trial sequential analysis. PLoS One 2014; 9(7): e101615.","DOI":"10.1371\/journal.pone.0101615"},{"key":"53767","doi-asserted-by":"crossref","unstructured":"Yin L, Teng J, Huang CJ, Zhang X, Xu D. Holmium laser enucleation of the prostate versus transurethral resection of the prostate: a systematic review and meta-analysis of randomized controlled trials. J Endourol 2013; 27(5): 604-11.","DOI":"10.1089\/end.2012.0505"},{"key":"53768","doi-asserted-by":"crossref","unstructured":"Naspro R, Suardi N, Salonia A, Scattoni V, Guazzoni G, Colombo R, et al. Holmium laser enucleation of the prostate versus open prostatectomy for prostates >70 g: 24-month follow-up. Eur Urol 2006; 50(3): 563-8.","DOI":"10.1016\/j.eururo.2006.04.003"},{"key":"53769","doi-asserted-by":"crossref","unstructured":"Schiavina R, Bianchi L, Giampaoli M, Borghesi M, Dababneh H, Chessa F, et al. Holmium laser prostatectomy in a tertiary Italian center: A prospective cost analysis in comparison with bipolar TURP and open prostatectomy. Arch Ital Urol Androl 2020; 92(2).","DOI":"10.4081\/aiua.2020.2.82"},{"key":"53770","doi-asserted-by":"crossref","unstructured":"Gurlen G, Karkin K. Does Holmium laser enucleation of the prostate (HoLEP) still have a steep learning curve? Our experience of 100 consecutive cases from Turkey. Arch Ital Urol Androl 2021; 93(4): 412-7.","DOI":"10.4081\/aiua.2021.4.412"},{"key":"53771","doi-asserted-by":"crossref","unstructured":"Ibrahim A, Alharbi M, Elhilali MM, Aube M, Carrier S. 18 Years of Holmium Laser Enucleation of the Prostate: A Single Center Experience. J Urol 2019; 202(4): 795-800.","DOI":"10.1097\/JU.0000000000000280"},{"key":"53772","doi-asserted-by":"crossref","unstructured":"Large T, Nottingham C, Stoughton C, Williams J, Jr., Krambeck A. Comparative Study of Holmium Laser Enucleation of the Prostate With MOSES Enabled Pulsed Laser Modulation. Urology 2020; 136: 196-201.","DOI":"10.1016\/j.urology.2019.11.029"},{"key":"53773","doi-asserted-by":"crossref","unstructured":"Nevo A, Faraj KS, Cheney SM, Moore JP, Stern KL, Borofsky M, et al. Holmium laser enucleation of the prostate using Moses 2.0 vs non-Moses: a randomised controlled trial. BJU Int 2021; 127(5): 553-9.","DOI":"10.1111\/bju.15265"},{"key":"53774","doi-asserted-by":"crossref","unstructured":"Fried NM, Murray KE. High-power thulium fiber laser ablation of urinary tissues at 1.94 microm. J Endourol 2005; 19(1): 25-31.","DOI":"10.1089\/end.2005.19.25"},{"key":"53775","doi-asserted-by":"crossref","unstructured":"Enikeev D, Glybochko P, Rapoport L, Gahan J, Gazimiev M, Spivak L, et al. A Randomized Trial Comparing The Learning Curve of 3 Endoscopic Enucleation Techniques (HoLEP, ThuFLEP, and MEP) for BPH Using Mentoring Approach-Initial Results. Urology 2018; 121: 51-7.","DOI":"10.1016\/j.urology.2018.06.045"},{"key":"53776","doi-asserted-by":"crossref","unstructured":"Enikeev D, Netsch C, Rapoport L, Gazimiev M, Laukhtina E, Snurnitsyna O, et al. Novel thulium fiber laser for endoscopic enucleation of the prostate: A prospective comparison with conventional transurethral resection of the prostate. Int J Urol 2019; 26(12): 1138-43.","DOI":"10.1111\/iju.14115"},{"key":"53777","doi-asserted-by":"crossref","unstructured":"Enikeev D, Okhunov Z, Rapoport L, Taratkin M, Enikeev M, Snurnitsyna O, et al. Novel Thulium Fiber Laser for Enucleation of Prostate: A Retrospective Comparison with Open Simple Prostatectomy. J Endourol 2019; 33(1): 16-21.","DOI":"10.1089\/end.2018.0791"},{"key":"53778","doi-asserted-by":"crossref","unstructured":"Elmansy H, Hodhod A, Kotb A, Prowse O, Shahrour W. Top-down Holmium Laser Enucleation of the Prostate: Technical Aspects and Early Outcomes. Urology 2019; 126: 236.","DOI":"10.1016\/j.urology.2019.01.019"},{"key":"53779","doi-asserted-by":"crossref","unstructured":"Elmansy H, Shabana W, Waugh M, Ahmad A, Hadi RA, Shahrour W. Top-down thulium fiber laser enucleation of the prostate: technical aspects. Cent European J Urol 2021; 74(2): 271.","DOI":"10.5173\/ceju.2021.0010.R1"},{"key":"53780","unstructured":"Palumbo P, Tellan G, Perotti B, Pacile MA, Vietri F, Illuminati G. Modified PADSS (Post Anaesthetic Discharge Scoring System) for monitoring outpatients discharge. Ann Ital Chir 2013; 84(6): 661-5."},{"key":"53781","doi-asserted-by":"crossref","unstructured":"Abdul-Muhsin H, Critchlow W, Navaratnam A, Gnecco J, Tay K, Girardo M, et al. Feasibility of holmium laser enucleation of the prostate as a 1-day surgery. World J Urol 2020; 38(4): 1017-25.","DOI":"10.1007\/s00345-019-02831-6"},{"key":"53782","doi-asserted-by":"crossref","unstructured":"Becker B, Netsch C, Glybochko P, Rapoport L, Taratkin M, Enikeev D. A Feasibility Study Utilizing the Thulium and Holmium Laser in Patients for the Treatment of Recurrent Benign Prostatic Hyperplasia after Previous Prostatic Surgery. Urol Int 2018; 101(2): 212-8.","DOI":"10.1159\/000489858"},{"key":"53783","doi-asserted-by":"crossref","unstructured":"Nottingham CU, Large T, Agarwal DK, Rivera ME, Krambeck AE. Comparison of Newly Optimized Moses Technology vs Standard Holmium:YAG for Endoscopic Laser Enucleation of the Prostate. J Endourol 2021; 35(9): 1393-9.","DOI":"10.1089\/end.2020.0996"},{"key":"53784","doi-asserted-by":"crossref","unstructured":"Doizi S, Germain T, Panthier F, Comperat E, Traxer O, Berthe L. Comparison of Holmium:YAG and Thulium Fiber Lasers on Soft Tissue: An Ex Vivo Study. J Endourol 2022.","DOI":"10.1089\/end.2021.0263"},{"key":"53785","doi-asserted-by":"crossref","unstructured":"Slade A, Agarwal D, Large T, Sahm E, Schmidt J, Rivera ME. Expanded Criteria Same Day Catheter Removal Following Holmium Laser Enucleation of the Prostate (HoLEP). J Endourol 2022.","DOI":"10.1089\/end.2022.0007"}],"container-title":["Archivio Italiano di Urologia e Andrologia"],"original-title":[],"link":[{"URL":"https:\/\/www.pagepressjournals.org\/index.php\/aiua\/article\/download\/aiua.2022.2.180\/10195","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.pagepressjournals.org\/index.php\/aiua\/article\/download\/aiua.2022.2.180\/10195","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,6,30]],"date-time":"2022-06-30T03:37:08Z","timestamp":1656560228000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.pagepressjournals.org\/index.php\/aiua\/article\/view\/aiua.2022.2.180"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,6,29]]},"references-count":22,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2022,6,30]]}},"URL":"https:\/\/doi.org\/10.4081\/aiua.2022.2.180","relation":{},"ISSN":["2282-4197","1124-3562"],"issn-type":[{"value":"2282-4197","type":"electronic"},{"value":"1124-3562","type":"print"}],"subject":[],"published":{"date-parts":[[2022,6,29]]}}}