{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T20:41:19Z","timestamp":1777581679720,"version":"3.51.4"},"reference-count":35,"publisher":"PAGEPress Publications","issue":"3","license":[{"start":{"date-parts":[[2022,9,26]],"date-time":"2022-09-26T00:00:00Z","timestamp":1664150400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arch Ital Urol Androl"],"abstract":"<jats:p>Introduction: Several mobile health applications (MHAs) have been developed to assist and improve the quality of life of patients affected by premature ejaculation, but the scientific quality and adherence to guidelines are not yet addressed. Materials and methods: On 25 May 2022, we conducted a search in the Apple App Store and Google Play Store. We reviewed all mobile apps from Apple App Store and Google Play Store for premature ejaculation and evaluated their usage in screening, prevention, management, and adherence to EAU guidelines. Results: In total 9 MHA were reviewed. All MHAs are geared towards the patient and provide information about diagnoses and treatment of PE. The mean score were 2.87, 3.69, 2.77, 2.55, 2.86 for Engagement, Functionality, Aesthetics, Information, and Subjective quality respectively. MHAs reported low and medium adherence to EAU guidelines. Conclusions: MHAs provide different services in many medical fields, including male sexual dysfunction. Their development is constantly increasing, but the problems of scientific validation, content, and quality are not yet solved. Much future research is necessary to improve the quality of the apps and promote new user designed, and high-quality apps.<\/jats:p>","DOI":"10.4081\/aiua.2022.3.328","type":"journal-article","created":{"date-parts":[[2022,9,26]],"date-time":"2022-09-26T14:32:41Z","timestamp":1664202761000},"page":"328-333","source":"Crossref","is-referenced-by-count":9,"title":["Premature ejaculation in the era of mobile health application: A current analysis and evaluation of adherence to EAU guidelines"],"prefix":"10.4081","volume":"94","author":[{"given":"Luigi","family":"Napolitano","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luigi","family":"Cirillo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giovanni Maria","family":"Fusco","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marco","family":"Abate","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alfonso","family":"Falcone","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vincenzo","family":"Morgera","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gianluigi","family":"Cacace","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luigi","family":"De Luca","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pasquale","family":"Reccia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Claudia","family":"Mirone","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Felice","family":"Crocetto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giuseppe","family":"Celentano","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Simone","family":"Morra","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Biagio","family":"Barone","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ciro","family":"Imbimbo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicola","family":"Longo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vincenzo","family":"Mirone","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roberto","family":"La Rocca","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2549","published-online":{"date-parts":[[2022,9,26]]},"reference":[{"key":"59719","doi-asserted-by":"crossref","unstructured":"Gao J, Zhang X, Su P, Shi K, Tang D, Hao Z, et al. Prevalence and impact of premature ejaculation in outpatients complaining of ejaculating prematurely: using the instruments of intravaginal ejaculatory latency time and patient-reported outcome measures. Int J Impot Res. maggio 2014;26(3):94\u20139.","DOI":"10.1038\/ijir.2013.42"},{"key":"59720","doi-asserted-by":"crossref","unstructured":"Sj\u00f6gren Fugl-Meyer K, Fugl-Meyer AR. Sexual disabilities are not singularities. Int J Impot Res. 1 dicembre 2002;14(6):487\u201393.","DOI":"10.1038\/sj.ijir.3900914"},{"key":"59721","doi-asserted-by":"crossref","unstructured":"Mirone V, Napolitano L, D\u2019Emmanuele di Villa Bianca R, Mitidieri E, Sorrentino R, Vanelli A, et al. A new original nutraceutical formulation ameliorates the effect of Tadalafil on clinical score and cGMP accumulation. Arch Ital Urol E Androl. 28 giugno 2021;93(2):221\u20136.","DOI":"10.4081\/aiua.2021.2.221"},{"key":"59722","doi-asserted-by":"crossref","unstructured":"Romano L, Granata L, Fusco F, Napolitano L, Cerbone R, Priadko K, et al. Sexual Dysfunction in Patients With Chronic Gastrointestinal and Liver Diseases: A neglected Issue. Sex Med Rev. 2 agosto 2021;S2050-0521(21)00039-1.","DOI":"10.1016\/j.sxmr.2021.02.002"},{"key":"59723","doi-asserted-by":"crossref","unstructured":"Barone B, Napolitano L, Abate M, Cirillo L, Reccia P, Passaro F, et al. The Role of Testosterone in the Elderly: What Do We Know? Int J Mol Sci. 24 marzo 2022;23(7):3535.","DOI":"10.3390\/ijms23073535"},{"key":"59724","doi-asserted-by":"crossref","unstructured":"Romano L, Pellegrino R, Sciorio C, Barone B, Gravina AG, Santonastaso A, et al. Erectile and sexual dysfunction in male and female patients with celiac disease: A cross-sectional observational study. Andrology. 14 aprile 2022;","DOI":"10.1111\/andr.13186"},{"key":"59725","doi-asserted-by":"crossref","unstructured":"Salonia A, Bettocchi C, Boeri L, Capogrosso P, Carvalho J, Cilesiz NC, et al. European Association of Urology Guidelines on Sexual and Reproductive Health\u20142021 Update: Male Sexual Dysfunction. Eur Urol. settembre 2021;80(3):333\u201357.","DOI":"10.1016\/j.eururo.2021.06.007"},{"key":"59726","doi-asserted-by":"crossref","unstructured":"Veettil Raveendran A, Agarwal A. Premature ejaculation - current concepts in the management: A narrative review. Int J Reprod Biomed IJRM [Internet]. 25 gennaio 2021 [citato 22 giugno 2022]; Disponibile su: https:\/\/knepublishing.com\/index.php\/ijrm\/article\/view\/8176","DOI":"10.18502\/ijrm.v19i1.8176"},{"key":"59727","unstructured":"InformedHealth.org [Internet]. Cologne, Germany: Institute for Quality and Efficiency in Health Care (IQWiG); 2006-. Premature ejaculation: What can I do on my own? 2019 Sep 12. Available from: https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK547551\/."},{"key":"59728","doi-asserted-by":"crossref","unstructured":"Iribarren SJ, Akande TO, Kamp KJ, Barry D, Kader YG, Suelzer E. Effectiveness of Mobile Apps to Promote Health and Manage Disease: Systematic Review and Meta-analysis of Randomized Controlled Trials. JMIR MHealth UHealth. 11 gennaio 2021;9(1):e21563.","DOI":"10.2196\/21563"},{"key":"59729","doi-asserted-by":"crossref","unstructured":"Milne-Ives M, Lam C, De Cock C, Van Velthoven MH, Meinert E. Mobile Apps for Health Behavior Change in Physical Activity, Diet, Drug and Alcohol Use, and Mental Health: Systematic Review. JMIR MHealth UHealth. 18 marzo 2020;8(3):e17046.","DOI":"10.2196\/17046"},{"key":"59730","doi-asserted-by":"crossref","unstructured":"Levine DM, Co Z, Newmark LP, Groisser AR, Holmgren AJ, Haas JS, et al. Design and testing of a mobile health application rating tool. Npj Digit Med. dicembre 2020;3(1):74.","DOI":"10.1038\/s41746-020-0268-9"},{"key":"59731","doi-asserted-by":"crossref","unstructured":"John Leon Singh H, Couch D, Yap K. Mobile Health Apps That Help With COVID-19 Management: Scoping Review. JMIR Nurs. 6 agosto 2020;3(1):e20596.","DOI":"10.2196\/20596"},{"key":"59732","doi-asserted-by":"crossref","unstructured":"Barone B, De Luca L, Napolitano L, Reccia P, Crocetto F, Creta M, et al. Lower urinary tract symptoms and mental health during COVID-19 pandemic. Arch Ital Urol E Androl. 29 marzo 2022;94(1):46\u201350.","DOI":"10.4081\/aiua.2022.1.46"},{"key":"59733","unstructured":"Napolitano L, Barone B, Crocetto F, Capece M, La Rocca R. The COVID-19 Pandemic: Is It A Wolf Consuming Fertility? Int J Fertil Steril. luglio 2020;14(2):159\u201360."},{"key":"59734","doi-asserted-by":"crossref","unstructured":"Sujarwoto S, Augia T, Dahlan H, Sahputri RAM, Holipah H, Maharani A. COVID-19 Mobile Health Apps: An Overview of Mobile Applications in Indonesia. Front Public Health. 4 maggio 2022;10:879695.","DOI":"10.3389\/fpubh.2022.879695"},{"key":"59735","doi-asserted-by":"crossref","unstructured":"Amor-Garc\u00eda M\u00c1, Collado-Borrell R, Escudero-Vilaplana V, Melgarejo-Ortu\u00f1o A, Herranz-Alonso A, Arranz Arija J\u00c1, et al. Assessing Apps for Patients with Genitourinary Tumors Using the Mobile Application Rating Scale (MARS): Systematic Search in App Stores and Content Analysis. JMIR MHealth UHealth. 23 luglio 2020;8(7):e17609.","DOI":"10.2196\/17609"},{"key":"59736","doi-asserted-by":"crossref","unstructured":"Rajani NB, Weth D, Mastellos N, Filippidis FT. Adherence of popular smoking cessation mobile applications to evidence-based guidelines. BMC Public Health. dicembre 2019;19(1):743.","DOI":"10.1186\/s12889-019-7084-7"},{"key":"59737","doi-asserted-by":"crossref","unstructured":"Vaggers S, Puri P, Wagenlehner F, Somani BK. A Content Analysis of Mobile Phone Applications for the Diagnosis, Treatment, and Prevention of Urinary Tract Infections, and Their Compliance with European Association of Urology Guidelines on Urological Infections. Eur Urol Focus. gennaio 2021;7(1):198\u2013204.","DOI":"10.1016\/j.euf.2020.02.002"},{"key":"59738","doi-asserted-by":"crossref","unstructured":"Escriche-Escuder A, De-Torres I, Rold\u00e1n-Jim\u00e9nez C, Mart\u00edn-Mart\u00edn J, Muro-Culebras A, Gonz\u00e1lez-S\u00e1nchez M, et al. Assessment of the Quality of Mobile Applications (Apps) for Management of Low Back Pain Using the Mobile App Rating Scale (MARS). Int J Environ Res Public Health. 9 dicembre 2020;17(24):9209.","DOI":"10.3390\/ijerph17249209"},{"key":"59739","doi-asserted-by":"crossref","unstructured":"Kernebeck S, Busse TS, B\u00f6ttcher MD, Weitz J, Ehlers J, Bork U. Impact of mobile health and medical applications on clinical practice in gastroenterology. World J Gastroenterol. 7 agosto 2020;26(29):4182\u201397.","DOI":"10.3748\/wjg.v26.i29.4182"},{"key":"59740","doi-asserted-by":"crossref","unstructured":"Mart\u00ednez-P\u00e9rez B, de la Torre-D\u00edez I, L\u00f3pez-Coronado M. Mobile Health Applications for the Most Prevalent Conditions by the World Health Organization: Review and Analysis. J Med Internet Res. 14 giugno 2013;15(6):e120.","DOI":"10.2196\/jmir.2600"},{"key":"59741","doi-asserted-by":"crossref","unstructured":"Optale G, Burigat S, Chittaro L, Riva G. Smartphone-Based Therapeutic Exercises for Men Affected by Premature Ejaculation: A Pilot Study. Sex Med. settembre 2020;8(3):461\u201371.","DOI":"10.1016\/j.esxm.2020.05.003"},{"key":"59742","doi-asserted-by":"crossref","unstructured":"Terhorst Y, Philippi P, Sander LB, Schultchen D, Paganini S, Bardus M, et al. Validation of the Mobile Application Rating Scale (MARS). Moitra E, curatore. PLOS ONE. 2 novembre 2020;15(11):e0241480.","DOI":"10.1371\/journal.pone.0241480"},{"key":"59743","doi-asserted-by":"crossref","unstructured":"Dantas LO, Carvalho C, Prando BC, McAlindon TE, da Silva Serr\u00e3o PRM. Mobile health technologies for the management of rheumatic diseases: a systematic review of online stores in Brazil. Clin Rheumatol. luglio 2021;40(7):2601\u20139.","DOI":"10.1007\/s10067-020-05561-y"},{"key":"59744","doi-asserted-by":"crossref","unstructured":"Moglia ML, Nguyen HV, Chyjek K, Chen KT, Casta\u00f1o PM. Evaluation of Smartphone Menstrual Cycle Tracking Applications Using an Adapted APPLICATIONS Scoring System. Obstet Gynecol. giugno 2016;127(6):1153\u201360.","DOI":"10.1097\/AOG.0000000000001444"},{"key":"59745","doi-asserted-by":"crossref","unstructured":"Page MJ, McKenzie JE, Bossuyt PM, Boutron I, Hoffmann TC, Mulrow CD, et al. The PRISMA 2020 statement: an updated guideline for reporting systematic reviews. BMJ. 29 marzo 2021;n71.","DOI":"10.1136\/bmj.n71"},{"key":"59746","unstructured":"Luigi Napolitano , Giovanni Maria Fusco , Luigi Cirillo , Marco Abate, Claudia Mirone,, Biagio Barone, Giuseppe Celentano 1, Roberto La Rocca 1, Vincenzo Mirone 1, Massimiliano Creta, Marco Capece. Erectile dysfunction and mobile phone applications: Quality, content and adherence to european association guidelines on male sexual dysfunction. Disponibile su: 10.4081\/aiua.2022.2"},{"key":"59747","doi-asserted-by":"crossref","unstructured":"Jupp JCY, Sultani H, Cooper CA, Peterson KA, Truong TH. Evaluation of mobile phone applications to support medication adherence and symptom management in oncology patients. Pediatr Blood Cancer. novembre 2018;65(11):e27278.","DOI":"10.1002\/pbc.27278"},{"key":"59748","doi-asserted-by":"crossref","unstructured":"Narrillos-Moraza \u00c1, G\u00f3mez-Mart\u00ednez-Sagrera P, Amor-Garc\u00eda M\u00c1, Escudero-Vilaplana V, Collado-Borrell R, Villanueva-Bueno C, et al. Mobile Apps for Hematological Conditions: Review and Content Analysis Using the Mobile App Rating Scale. JMIR MHealth UHealth. 16 febbraio 2022;10(2):e32826.","DOI":"10.2196\/32826"},{"key":"59749","doi-asserted-by":"crossref","unstructured":"Kwan YH, Ong WJ, Xiong M, Leung YY, Phang JK, Wang CTM, et al. Evaluation of Mobile Apps Targeted at Patients With Spondyloarthritis for Disease Monitoring: Systematic App Search. JMIR MHealth UHealth. 28 ottobre 2019;7(10):e14753.","DOI":"10.2196\/14753"},{"key":"59750","doi-asserted-by":"crossref","unstructured":"Knitza J, Tascilar K, Messner EM, Meyer M, Vossen D, Pulla A, et al. German Mobile Apps in Rheumatology: Review and Analysis Using the Mobile Application Rating Scale (MARS). JMIR MHealth UHealth. 5 agosto 2019;7(8):e14991.","DOI":"10.2196\/14991"},{"key":"59751","doi-asserted-by":"crossref","unstructured":"Jiang M, Yan G, Deng H, Liang H, Lin Y, Zhang X. The efficacy of regular penis\u2010root masturbation, versus Kegel exercise in the treatment of primary premature ejaculation: A quasi\u2010randomised controlled trial. Andrologia [Internet]. febbraio 2020 [citato 22 giugno 2022];52(1). Disponibile su: https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/and.13473","DOI":"10.1111\/and.13473"},{"key":"59752","doi-asserted-by":"crossref","unstructured":"Pastore AL, Palleschi G, Fuschi A, Maggioni C, Rago R, Zucchi A, et al. Pelvic floor muscle rehabilitation for patients with lifelong premature ejaculation: a novel therapeutic approach. Ther Adv Urol. giugno 2014;6(3):83\u20138.","DOI":"10.1177\/1756287214523329"},{"key":"59753","doi-asserted-by":"crossref","unstructured":"Pischedda A, Fusco F, Curreli A, Grimaldi G, Pirozzi Farina F. Pelvic floor and sexual male dysfunction. 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