{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,23]],"date-time":"2025-10-23T17:04:18Z","timestamp":1761239058391,"version":"3.40.5"},"reference-count":21,"publisher":"PAGEPress Publications","license":[{"start":{"date-parts":[[2023,2,22]],"date-time":"2023-02-22T00:00:00Z","timestamp":1677024000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arch Ital Urol Androl"],"abstract":"<jats:p>Objective: The major strengths of surgical treatment of benign prostatic hyperplasia with laser are reduced morbidity compared to endoscopic resec-tion. No studies analysed the different risk of intra\/peri-opera-tive events between patients undergoing Thulium and GreenLight procedures.Materials and methods: We retrospectively reviewed 100 con-secutive cases undergoing GreenLight vaporization and Thulium procedures performed during the learning curve of two expert endoscopic surgeons. Pre-operative data, intra and post-opera-tive events at 90 days were analysed. Results: Patients on antiplatelet\/anticoagulant therapy were pre-dominant in the Green group (p &lt; 0.0001). Rates of blood trans-fusion (p &lt; 0.0038), use of resectoscope (p &lt; 0.0086), and tran-sient stress urinary incontinence were statistically higher in the Thulium group. On the contrary conversions to TURP(p &lt; 0.023) were more frequent in GreenLight patients. Readmissions were more frequently necessary in GreenLight group (24%) vs. Thulium group (26.6%). The overall complica-tion rate in GreenLight and Thulium groups were 31% and 53%respectively; Clavien 3b complications were 13% in Thulium patients versus 1% in GreenLight patients.Conclusions: GreenLight and Thulium treatments show similar safety pro\ufb01les. Randomized controlled trial are needed to better clarify the rate of major complications in Thulium group, and the incidence of post-operative storage symptoms in these patients\u2019 populations.<\/jats:p>","DOI":"10.4081\/aiua.2023.11101","type":"journal-article","created":{"date-parts":[[2023,2,22]],"date-time":"2023-02-22T15:33:35Z","timestamp":1677080015000},"source":"Crossref","is-referenced-by-count":1,"title":["Safety pro\ufb01le of treatment with greenlight versus  Thulium Laser for benign prostatic hyperplasia"],"prefix":"10.4081","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2072-114X","authenticated-orcid":false,"given":"Davide","family":"Campobasso","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antonio","family":"Barbieri","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tommaso","family":"Bocchialini","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gian Luigi","family":"Pozzoli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francesco","family":"Dinale","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francesco","family":"Facchini","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5497-4722","authenticated-orcid":false,"given":"Marco Serafino","family":"Grande","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jean Emmanuel","family":"Kwe","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michelangelo","family":"Larosa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giulio","family":"Guarino","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Davide","family":"Mezzogori","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elisa","family":"Simonetti","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3066-9798","authenticated-orcid":false,"given":"Francesco","family":"Ziglioli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antonio","family":"Frattini","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Umberto Vittorio","family":"Maestroni","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2549","published-online":{"date-parts":[[2023,2,22]]},"reference":[{"key":"70824","unstructured":"Gravas S, Cornu JN, Gacci M, et al. EAU Guidelines on Management of Non-Neurogenic Male Lower Urinary Tract Symptoms (LUTS), incl. Benign Prostatic Obstruction (BPO). Edn. presented at the EAU Annual Congress Amsterdam 2020. ISBN 978-94-92671-07-3. EAU Guidelines Of\ufb01ce, Arnhem, The Netherlands. http:\/\/uroweb.org\/guidelines\/compilations-of-all-guidelines\/"},{"key":"70825","doi-asserted-by":"crossref","unstructured":"Fallara G, Capogrosso P, Schifano N, et al. Ten-year Follow-up Results After Holmium Laser Enucleation of the Prostate. Eur Urol Focus. 2021; 7:612-617.","DOI":"10.1016\/j.euf.2020.05.012"},{"key":"70826","doi-asserted-by":"crossref","unstructured":"Campobasso D, Marchioni M, De Nunzio C, et al. Predictors of re-intervention after greenlight laser photoselective vaporization of the prostate: multicenter long\/mid-term follow-up experience. Mini-invasive Surgery. 2021; 5:45.","DOI":"10.20517\/2574-1225.2021.92"},{"key":"70827","doi-asserted-by":"crossref","unstructured":"Castellani D, Pirola GM, Pacchetti A, et al. State of the Art of Thulium Laser Enucleation and Vapoenucleation of the Prostate: A Systematic Review. Urology. 2020; 136:19-34.","DOI":"10.1016\/j.urology.2019.10.022"},{"key":"70828","doi-asserted-by":"crossref","unstructured":"Enikeev D, Morozov A, Taratkin M, et al. Systematic review of the endoscopic enucleation of the prostate learning curve. World J Urol. 2021; 39:2427-2438.","DOI":"10.1007\/s00345-020-03451-1"},{"key":"70829","doi-asserted-by":"crossref","unstructured":"Naspro R, Gomez Sancha F, Manica M, et al. From \"gold stan-dard\" resection to reproducible \"future standard\" endoscopic enucle-ation of the prostate: what we know about anatomical enucleation. Minerva Urol Nefrol. 2017; 69:446-458.","DOI":"10.23736\/S0393-2249.17.02834-X"},{"key":"70830","doi-asserted-by":"crossref","unstructured":"Campobasso D, Ferrari G, Frattini A. Greenlight laser: a laser for every prostate and every urologist. World J Urol. 2022; 40:295-296.","DOI":"10.1007\/s00345-020-03499-z"},{"key":"70831","doi-asserted-by":"crossref","unstructured":"Cindolo L, Ruggera L, Destefanis P, et al. Vaporize, anatomically vaporize or enucleate the prostate? The \ufb02exible use of the GreenLight laser. Int Urol Nephrol. 2017; 49:405-411.","DOI":"10.1007\/s11255-016-1494-6"},{"key":"70832","doi-asserted-by":"crossref","unstructured":"Mamoulakis C, Efthimiou I, Kazoulis S, et al. The modi\ufb01ed Clavien classi\ufb01cation system: a standardized platform for reporting complications in transurethral resection of the prostate. World J Urol. 2011; 29:205-210.","DOI":"10.1007\/s00345-010-0566-y"},{"key":"70833","doi-asserted-by":"crossref","unstructured":"Leonardo C, Lombardo R, Cindolo L, et al. What is the standard surgical approach to large volume BPE? Systematic review of existing randomized clinical trials. Minerva Urol Nefrol. 2020; 72:22-29.","DOI":"10.23736\/S0393-2249.19.03589-6"},{"key":"70834","doi-asserted-by":"crossref","unstructured":"Castellani D, Di Rosa M, Gasparri L, et al. Thulium Laser Vapoenucleation of the Prostate (ThuVEP) in Men at High Cardiovascular Risk and on Antithrombotic Therapy: A Single-Center Experience. J Clin Med. 2020; 9:917.","DOI":"10.3390\/jcm9040917"},{"key":"70835","doi-asserted-by":"crossref","unstructured":"Meskawi M, Hueber PA, Valdivieso R, et al. Complications and functional outcomes of high-risk patient with cardiovascular disease on antithrombotic medication treated with the 532-nm-laser photo-vaporization Greenlight XPS-180 W for benign prostate hyperplasia. World J Urol. 2019; 37:1671-1678.","DOI":"10.1007\/s00345-018-2560-8"},{"key":"70836","doi-asserted-by":"crossref","unstructured":"Campobasso D, Marchioni M, Altieri V, et al. GreenLight Photoselective Vaporization of the Prostate: One Laser for Different Prostate Sizes. J Endourol. 2020; 34:54-62.","DOI":"10.1089\/end.2019.0478"},{"key":"70837","unstructured":"Campobasso D, Acampora A, De Nunzio C, et al. Post-Operative Acute Urinary Retention After Greenlight Laser. Analysis Of Risk Factors from A Multicentric Database. Urol J. 2021; 18:693-698."},{"key":"70838","doi-asserted-by":"crossref","unstructured":"Mattevi D, Luciani L, Spina R, et al. Comparison of GreenLight 180-W XPS laser vaporization versus transurethral resection of the prostate: Outcomes of a single regional center. Arch Ital Urol Androl. 2020; 92:169-172","DOI":"10.4081\/aiua.2020.3.169"},{"key":"70839","doi-asserted-by":"crossref","unstructured":"Castellucci R, Marchioni M, Fasolis G, et al. The safety and fea-sibility of the simultaneous use of 180-W GreenLight laser for prostate vaporization during concomitant surgery. Arch Ital Urol Androl. 2020; 92:297-301","DOI":"10.4081\/aiua.2020.4.297"},{"key":"70840","doi-asserted-by":"crossref","unstructured":"Elmansy H, Hodhod A, Elshafei A, et al. Comparative analysis of MOSESTM technology versus novel thulium \ufb01ber laser (TFL) for transurethral enucleation of the prostate: A single-institutional study. Arch Ital Urol Androl. 2022; 94:180-185.","DOI":"10.4081\/aiua.2022.2.180"},{"key":"70841","doi-asserted-by":"crossref","unstructured":"Palmero-Mart\u00ed JL, Panach-Navarrete J, Valls-Gonz\u00e1lez L, et al. Comparative study between thulium laser (Tm: YAG) 150W and greenlight laser (LBO:ND-YAG) 120W for the treatment of benign prostatic hyperpplasia: Short-term ef\ufb01cacy and security. Actas Urol Esp. 2017; 41:188-193.","DOI":"10.1016\/j.acuroe.2017.02.007"},{"key":"70842","doi-asserted-by":"crossref","unstructured":"Castellani D, Cindolo L, De Nunzio C, et al. Comparison Between Thulium Laser VapoEnucleation and GreenLight Laser Photoselective Vaporization of the Prostate in Real-Life Setting: Propensity Score Analysis. Urology. 2018; 121:147-152.","DOI":"10.1016\/j.urology.2018.09.007"},{"key":"70843","doi-asserted-by":"crossref","unstructured":"Cindolo L, De Nunzio C, Greco F, et al. Standard vs. anatomical 180-W GreenLight laser photoselective vaporization of the prostate: a propensity score analysis. World J Urol. 2018; 36:91-97.","DOI":"10.1007\/s00345-017-2106-5"},{"key":"70844","doi-asserted-by":"crossref","unstructured":"Kyriazis I, Swiniarski PP, Jutzi S, et al. Transurethral anatomical enucleation of the prostate with Tm:YAG support (ThuLEP): Review of the literature on a novel surgical approach in the management of benign prostatic enlargement. World J Urol. 2015; 33:525-30.","DOI":"10.1007\/s00345-015-1529-0"}],"container-title":["Archivio Italiano di Urologia e Andrologia"],"original-title":[],"link":[{"URL":"https:\/\/www.pagepressjournals.org\/index.php\/aiua\/article\/download\/11101\/10727","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.pagepressjournals.org\/index.php\/aiua\/article\/download\/11101\/10727","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,2,22]],"date-time":"2023-02-22T15:33:51Z","timestamp":1677080031000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.pagepressjournals.org\/index.php\/aiua\/article\/view\/11101"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,2,22]]},"references-count":21,"URL":"https:\/\/doi.org\/10.4081\/aiua.2023.11101","relation":{},"ISSN":["2282-4197","1124-3562"],"issn-type":[{"type":"electronic","value":"2282-4197"},{"type":"print","value":"1124-3562"}],"subject":[],"published":{"date-parts":[[2023,2,22]]}}}