{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,12]],"date-time":"2025-02-12T05:19:54Z","timestamp":1739337594194,"version":"3.37.0"},"reference-count":6,"publisher":"PAGEPress Publications","license":[{"start":{"date-parts":[[2025,2,11]],"date-time":"2025-02-11T00:00:00Z","timestamp":1739232000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arch Ital Urol Androl"],"abstract":"<jats:p>To the Editor,\nWe conducted a retrospective study to demonstrate that it is possible to achieve better therapeutic outcomes through combining perilesional injections of pentoxifylline (PTX) with oral antioxidants and the local application of a cream containing\u00a0antioxidants and a gel containing diclofenac in patients with Peyronie's disease (PD)...<\/jats:p>","DOI":"10.4081\/aiua.2025.13525","type":"journal-article","created":{"date-parts":[[2025,2,11]],"date-time":"2025-02-11T09:00:42Z","timestamp":1739264442000},"source":"Crossref","is-referenced-by-count":0,"title":["Treatment with perilesional injections of pentoxifylline in patients with Peyronie's disease improves the therapeutic effect of oral and topical antioxidant therapy"],"prefix":"10.4081","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7312-1514","authenticated-orcid":false,"given":"Gianni","family":"Paulis","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1309-4934","authenticated-orcid":false,"given":"Andrea","family":"Paulis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-8197-4111","authenticated-orcid":false,"given":"Giovanni","family":"De Giorgio","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2549","published-online":{"date-parts":[[2025,2,11]]},"reference":[{"key":"158582","doi-asserted-by":"crossref","unstructured":"Pryor JP, Ralph DJ. Clinical presentations of Peyronie\u2019s disease. Int. J Impot Res. 2002; 14:414\u2013417.","DOI":"10.1038\/sj.ijir.3900877"},{"key":"158583","doi-asserted-by":"crossref","unstructured":"Garaffa G, Trost LW, Serefoglu EC, et al. Understanding the course of Peyronie's disease. Int J Clin Pract. 2013; 67:781\u2013788.","DOI":"10.1111\/ijcp.12129"},{"key":"158584","doi-asserted-by":"crossref","unstructured":"Brant WO, Dean RC, Lue TF. Treatment of Peyronie's disease with oral pentoxifylline. Nat Clin Pract Urol. 2006; 3:111-115.","DOI":"10.1038\/ncpuro0409"},{"key":"158585","doi-asserted-by":"crossref","unstructured":"Smith JF, Shindel AW, Huang YC, et al. Pentoxifylline treatment and penile calcifications in men with Peyronie\u2019s disease. Asian J Androl. 2011; 13:322\u2013325.","DOI":"10.1038\/aja.2010.117"},{"key":"158586","doi-asserted-by":"crossref","unstructured":"Ibrahim A, Gazzard L, Alharbi M, et al. Evaluation of Oral Pentoxifylline, Colchicine, and Penile Traction for the Management of Peyronie's Disease. Sex Med. 2019; 7:459\u2013463.","DOI":"10.1016\/j.esxm.2019.07.003"},{"key":"158587","doi-asserted-by":"crossref","unstructured":"Paulis G, Barletta D, Turchi P, et al. Efficacy and safety evaluation of pentoxifylline associated with other antioxidants in medical treatment of Peyronie\u2019s disease: A case-control study. Res Rep Urol. 2016; 8:1-10.","DOI":"10.2147\/RRU.S97194"}],"container-title":["Archivio Italiano di Urologia e Andrologia"],"original-title":[],"link":[{"URL":"https:\/\/www.pagepressjournals.org\/aiua\/article\/download\/13525\/12823","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.pagepressjournals.org\/aiua\/article\/download\/13525\/12823","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,2,11]],"date-time":"2025-02-11T09:00:48Z","timestamp":1739264448000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.pagepressjournals.org\/aiua\/article\/view\/13525"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,2,11]]},"references-count":6,"URL":"https:\/\/doi.org\/10.4081\/aiua.2025.13525","relation":{},"ISSN":["2282-4197","1124-3562"],"issn-type":[{"value":"2282-4197","type":"electronic"},{"value":"1124-3562","type":"print"}],"subject":[],"published":{"date-parts":[[2025,2,11]]}}}