{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T13:02:48Z","timestamp":1790341368199,"version":"4.1.0"},"reference-count":14,"publisher":"PAGEPress Publications","issue":"3","license":[{"start":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T00:00:00Z","timestamp":1790294400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arch Ital Urol Androl"],"abstract":"<jats:p>Background: Benign prostatic hyperplasia is a leading cause of lower urinary tract symptoms and bladder outlet obstruction in ageing men. Transurethral resection of the prostate remains a benchmark surgical treatment, although contemporary practice has been challenged by less invasive techniques. We aimed to evaluate real-world effectiveness and safety outcomes of transurethral resection of the prostate for benign prostatic obstruction.\nMaterials and Methods: Single-center, retrospective, observational cohort study including all consecutive patients who underwent TURP between October 2020 and March 2025. Baseline, perioperative and postoperative variables were analyzed, including 30-day emergency department (ED) visits, catheter-free status among previously catheterized patients, persistence of lower urinary tract symptoms (LUTS), and uroflowmetry parameters.\nResults: A total of 530 patients were included (median age 69 years). Median hospitalization was 2 days, with 15.7% discharged within 24 hours. Within 30 days, 109 patients (20.6%) attended the ED, mainly due to acute urinary retention (39.4%) and hematuria (31.2%); perioperative hemoglobin drop was the only independent predictor of ED attendance (OR 1.267; p = 0.004). Among chronically catheterized patients, 89.4% became catheter-free postoperatively. Prostate volume was independently associated with longer hospitalization and persistent postoperative LUTS. Antithrombotic monotherapy was not significantly associated with greater hemoglobin drop, catheterization duration, or ED attendance. Maximum urinary flow rate improved significantly from 8.20 to 19.47 mL\/s (p &lt; 0.001).\nConclusions: This real-world cohort confirms TURP as an effective and safe procedure for benign prostatic obstruction, providing objective functional improvement and a high catheter-free rate. ED visits, mainly due to urinary retention and hematuria, represent a relevant target for pathway optimization. Standardized antithrombotic protocols and structured postoperative follow-up may further improve safety and quality of care.<\/jats:p>","DOI":"10.4081\/aiua.2026.15893","type":"journal-article","created":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T12:45:59Z","timestamp":1790340359000},"source":"Crossref","is-referenced-by-count":0,"title":["Real-world outcomes of transurethral resection of the prostate: a Portuguese cohort"],"prefix":"10.4081","volume":"98","author":[{"given":"Rui","family":"Pedrosa","sequence":"first","affiliation":[{"name":"Department of Urology and Renal Transplantation, ULS Coimbra"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patricia","family":"Pa\u00e7o","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, University of Coimbra"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tiago","family":"Sousa","sequence":"additional","affiliation":[{"name":"Department of Urology and Renal Transplantation, ULS Coimbra"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andr\u00e9","family":"R\u00eago","sequence":"additional","affiliation":[{"name":"Department of Urology and Renal Transplantation, ULS Coimbra"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edgar","family":"Tavares Silva","sequence":"additional","affiliation":[{"name":"Department of Urology and Renal Transplantation, ULS Coimbra"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paulo","family":"Temido","sequence":"additional","affiliation":[{"name":"Department of Urology and Renal Transplantation, ULS Coimbra"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arnaldo","family":"Figueiredo","sequence":"additional","affiliation":[{"name":"Department of Urology and Renal Transplantation, ULS Coimbra"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2549","published-online":{"date-parts":[[2026,9,25]]},"reference":[{"key":"253271","unstructured":"1. Awedew AF, Han H, Abbasi B, et al. The global, regional, and national burden of benign prostatic hyperplasia in 204 countries and territories from 2000 to 2019: a systematic analysis for the Global Burden of Disease Study 2019. Lancet Healthy Longev. 2022;3:e754-e776."},{"key":"253272","unstructured":"2. Hashim H, Herrmann TRW, Malde S, et al. EAU Guidelines on Management of Non-neurogenic Male Lower Urinary Tract Symptoms. Arnhem: EAU Guidelines Office; 2026."},{"key":"253273","doi-asserted-by":"crossref","unstructured":"3. Goueli R, Badlani GH, Welliver C, et al. Management of lower urinary tract symptoms attributed to benign prostatic hyperplasia: AUA Guideline (2026) Part III: Procedural\/Surgical Management. J Urol. 2026:101097JU0000000000005099.","DOI":"10.1097\/JU.0000000000005099"},{"key":"253274","doi-asserted-by":"crossref","unstructured":"4. Reich O, Gratzke C, Bachmann A, et al. Morbidity, mortality and early outcome of transurethral resection of the prostate: a prospective multicenter evaluation of 10,654 patients. J Urol. 2008; 180:246-249.","DOI":"10.1016\/j.juro.2008.03.058"},{"key":"253275","doi-asserted-by":"crossref","unstructured":"5. Yin L, Teng J, Huang CJ, et al. Holmium laser enucleation of the prostate versus transurethral resection of the prostate: a systematic review and meta-analysis of randomized controlled trials. J Endourol. 2013; 27:604-611.","DOI":"10.1089\/end.2012.0505"},{"key":"253276","doi-asserted-by":"crossref","unstructured":"6. Chen F, Chen Y, Zou Y, et al. Comparison of holmium laser enucleation and transurethral resection of prostate in benign prostatic hyperplasia: a systematic review and meta-analysis. J Int Med Res. 2023; 51:03000605231190763.","DOI":"10.1177\/03000605231190763"},{"key":"253277","doi-asserted-by":"crossref","unstructured":"7. Porto JG, Bhatia AM, Bhat A, et al. Evaluating transurethral resection of the prostate over twenty years: a systematic review and metaanalysis of randomized clinical trials. World J Urol. 2024; 42:639.","DOI":"10.1007\/s00345-024-05332-3"},{"key":"253278","doi-asserted-by":"crossref","unstructured":"8. Antoniou V, Edris F, Akpobire W, et al. Surgical outcomes for elderly patients undergoing transurethral resection of the prostate for chronic urinary retention and proposal of a management algorithm. J Endourol. 2023; 37:581-6.","DOI":"10.1089\/end.2022.0654"},{"key":"253279","doi-asserted-by":"crossref","unstructured":"9. Lotterst\u00e4tter M, Seklehner S, Wimpissinger F, et al. Transurethral resection of the prostate in 85+ patients: a retrospective, multicentre study. World J Urol. 2022; 40:3015-3020.","DOI":"10.1007\/s00345-022-04179-w"},{"key":"253280","doi-asserted-by":"crossref","unstructured":"10. Palmisano F, Boeri L, Fontana M, et al. Incidence and predictors of readmission within 30 days of transurethral resection of the prostate: a single center European experience. Sci Rep. 2018; 8:6575.","DOI":"10.1038\/s41598-018-25069-5"},{"key":"253281","doi-asserted-by":"crossref","unstructured":"11. Ru\u0308hle A, Blarer J, Oehme F, et al. Safety and effectiveness of bipolar transurethral resection of the prostate in patients under ongoing oral anticoagulation with coumarins or antiplatelet drug therapy compared to patients without anticoagulation\/antiplatelet therapy. J Endourol. 2019; 33:455-62.","DOI":"10.1089\/end.2018.0879"},{"key":"253282","doi-asserted-by":"crossref","unstructured":"12. Pranata FH, Kloping YP, Hidayatullah F, et al. The role of tranexamic acid in reducing bleeding during transurethral resection of the prostate: an updated systematic review and meta-analysis of randomized controlled trials. Indian J Urol. 2022; 38:258-67.","DOI":"10.4103\/iju.iju_98_22"},{"key":"253283","doi-asserted-by":"crossref","unstructured":"13. Zhang Y, Liu M, Sun F, et al. The efficacy of tranexamic acid in reducing intraoperative bleeding during transurethral resection of the prostate for benign prostatic hyperplasia: a systematic review and meta-analysis of randomized controlled trials. PeerJ 14: e20780.","DOI":"10.7717\/peerj.20780"},{"key":"253284","doi-asserted-by":"crossref","unstructured":"14. Rassweiler J, Teber D, Kuntz R, Hofmann R. Complications of transurethral resection of the prostate (TURP): incidence, management, and prevention. Eur Urol. 2006; 50:969-79.","DOI":"10.1016\/j.eururo.2005.12.042"}],"container-title":["Archivio Italiano di Urologia e Andrologia"],"original-title":[],"link":[{"URL":"https:\/\/www.pagepressjournals.org\/aiua\/article\/download\/15893\/14518","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.pagepressjournals.org\/aiua\/article\/download\/15893\/14518","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T12:46:04Z","timestamp":1790340364000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.pagepressjournals.org\/aiua\/article\/view\/15893"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9,25]]},"references-count":14,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2026,9,25]]}},"URL":"https:\/\/doi.org\/10.4081\/aiua.2026.15893","relation":{},"ISSN":["2282-4197","1124-3562"],"issn-type":[{"value":"2282-4197","type":"electronic"},{"value":"1124-3562","type":"print"}],"subject":[],"published":{"date-parts":[[2026,9,25]]}}}