{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,4,9]],"date-time":"2025-04-09T06:06:54Z","timestamp":1744178814068},"reference-count":9,"publisher":"MDPI AG","issue":"3","license":[{"start":{"date-parts":[[2012,7,4]],"date-time":"2012-07-04T00:00:00Z","timestamp":1341360000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinics and Practice"],"abstract":"<jats:p>Atrial septal defect (ASD) is usually asymptomatic in infancy, unless pulmonary hypertension or severe co-morbidity is present. We report a case of a 4-week-old infant with moderate- sized ASD, small patent ductus arteriosus (PDA), and a borderline sized left ventricle that developed heart failure. Despite the relatively small diameter of the ASD, this defect influenced the mechanism of heart failure significantly. After surgical closure of both PDA and ASD, the signs of pulmonary hypertension resolved and the patient developed a normal sized left ventricle. This report illustrates that the presence of a small ASD in combination with a marginal left ventricle may result in inadequate left ventricular filling, pulmonary hypertension and heart failure.<\/jats:p>","DOI":"10.4081\/cp.2012.e69","type":"journal-article","created":{"date-parts":[[2012,7,5]],"date-time":"2012-07-05T02:07:04Z","timestamp":1341454024000},"page":"e69","source":"Crossref","is-referenced-by-count":1,"title":["Small Atrial Septal Defect Associated with Heart Failure in an Infant with a Marginal Left Ventricle"],"prefix":"10.3390","volume":"2","author":[{"given":"Sandra D.K.","family":"Kingma","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lukas A.","family":"Rammeloo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vladimir","family":"Sojak","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jaroslav","family":"Hruda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2012,7,4]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1007\/s00246-007-9052-8","article-title":"Atrial septal defect: spectrum of care","volume":"29","author":"Kharouf","year":"2008","journal-title":"Pediatr Cardiol"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"784","DOI":"10.1136\/adc.56.10.784","article-title":"Correction of isolated secundum atrial septal defect in infancy","volume":"56","author":"Bull","year":"1981","journal-title":"Arch Dis Child"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1016\/j.amjcard.2008.03.061","article-title":"Frequency of severe pulmonary hypertension complicating isolated atrial septal defect in infancy","volume":"102","author":"Groetschmann","year":"2008","journal-title":"Am J Cardiol"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1016\/0002-8703(73)90164-6","article-title":"Symptomatic atrial septal defect in infants","volume":"85","author":"Dimich","year":"1973","journal-title":"Am Heart J"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"528","DOI":"10.1007\/PL00021008","article-title":"Atrial septal defect with failure to thrive in infancy: hidden pulmonary vascular disease?","volume":"23","author":"Andrews","year":"2002","journal-title":"Pediatr Cardiol"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"1353","DOI":"10.1016\/j.jtcvs.2004.10.007","article-title":"Need for closure of secundum atrial septal defect in infancy","volume":"129","author":"Lammers","year":"2005","journal-title":"J Thorac Cardiovasc Surg"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1016\/j.ijcard.2006.12.020","article-title":"Left superior vena cava in pediatric cardiology associated with extra-cardiac anomalies","volume":"123","author":"Postema","year":"2008","journal-title":"Int J Cardiol"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"480","DOI":"10.1016\/S0002-9149(03)00675-1","article-title":"Usefulness of the mitral valve Z score in predicting the need to close moderate-to large-sized atrial septal defects in infants with aortic coarctation","volume":"92","author":"Schroeder","year":"2003","journal-title":"Am J Cardiol"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"442","DOI":"10.1111\/j.1747-0803.2007.00140.x","article-title":"Device closure of a secundum atrial septal defect in a 4-month-old infant with a marginal left ventricle following coarctation repair","volume":"2","author":"Jean-St-Michel","year":"2007","journal-title":"Congenit Heart Dis"}],"container-title":["Clinics and Practice"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2039-7283\/2\/3\/e69\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,2,10]],"date-time":"2022-02-10T06:15:44Z","timestamp":1644473744000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2039-7283\/2\/3\/e69"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,7,4]]},"references-count":9,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2012,10]]}},"alternative-id":["cp.2012.e69"],"URL":"https:\/\/doi.org\/10.4081\/cp.2012.e69","relation":{},"ISSN":["2039-7283"],"issn-type":[{"value":"2039-7283","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,7,4]]}}}