{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T13:24:23Z","timestamp":1791293063157,"version":"4.1.0"},"reference-count":17,"publisher":"MDPI AG","issue":"2","license":[{"start":{"date-parts":[[2016,7,4]],"date-time":"2016-07-04T00:00:00Z","timestamp":1467590400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinics and Practice"],"abstract":"<jats:p>Severe diarrheal illness in children can be attributed to a number of different microbiological agents. Without appropriate microbiological testing of stool samples, patients who present with multiple days of severe diarrhea might have a delay in proper diagnosis and treatment. Here, we report a case of an immunocompetent pediatric patient presenting with acute cryptosporidiosis. Humans and bovine species are known hosts of cryptosporidium and several studies have evaluated the zoonotic transmission of cryptosporidium from cattle to humans. Adding diagnostic tests for cryptosporidium like Ziehl-Neelsen staining of stool or fecal rapid antigen detection techniques should be considered in the workup of patients presenting with undifferentiated, severe diarrheal illness, especially in those who have close contact with livestock.<\/jats:p>","DOI":"10.4081\/cp.2016.837","type":"journal-article","created":{"date-parts":[[2016,7,4]],"date-time":"2016-07-04T14:10:26Z","timestamp":1467641426000},"page":"837","source":"Crossref","is-referenced-by-count":13,"title":["Acute, Severe Cryptosporidiosis in an Immunocompetent Pediatric Patient"],"prefix":"10.3390","volume":"6","author":[{"given":"Caitlin","family":"Tallant","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrick","family":"Huddleston","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Asim","family":"Alshanberri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Subhasis","family":"Misra","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2016,7,4]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"7","DOI":"10.3201\/eid1701.P11101","article-title":"Foodborne illness acquired in the United States-major pathogens","volume":"17","author":"Scallan","year":"2011","journal-title":"Emerg Infect Dis"},{"key":"ref2","first-page":"197","article-title":"The global burden of diarrheal disease, as estimated from studies published between 1992 and 2000","volume":"81","author":"Kosek","year":"2003","journal-title":"Bull World Health Organ"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1016\/S1471-4922(02)02253-5","article-title":"Updating the DALYs for diarrhoeal disease","volume":"18","author":"Guerrant","year":"2002","journal-title":"Trends Parasitol"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1017\/S0950268801006628","article-title":"A population-based estimate of the burden of diarrhoeal illness in the United States: FoodNet, 1996-7","volume":"129","author":"Herikstad","year":"2002","journal-title":"Epidemiol Infect"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1056\/NEJMcp031534","article-title":"Acute infectious diarrhea","volume":"350","author":"Thielman","year":"2004","journal-title":"N Eng J Med"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"2944","DOI":"10.1128\/JCM.42.7.2944-2951.2004","article-title":"Risk factors for sporadic cryptosporidiosis among immunocompetent persons in the United States from 1999 to 2001","volume":"42","author":"Roy","year":"2004","journal-title":"J Clin Microbiol"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1586\/eri.09.24","article-title":"Treatment of cryptosporidiosis","volume":"7","author":"Pantenburg","year":"2009","journal-title":"Exp Rev Anti Infect Ther"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"458","DOI":"10.1097\/MPG.0b013e318054b09b","article-title":"Cryptosporidium infection in patients with primary immunodeficiencies","volume":"45","author":"Wolska-Kusnierz","year":"2007","journal-title":"Pediatr Gastroenterol Nutr"},{"key":"ref9","first-page":"1","article-title":"Surveillance for waterborne disease outbreaks and other health events associated with recreational water - 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