{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,7,27]],"date-time":"2024-07-27T15:12:17Z","timestamp":1722093137528},"reference-count":19,"publisher":"MDPI AG","issue":"3","license":[{"start":{"date-parts":[[2016,10,10]],"date-time":"2016-10-10T00:00:00Z","timestamp":1476057600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinics and Practice"],"abstract":"<jats:p>Adrenal hemangioma is an uncommon benign vascular tumor that is often discovered incidentally. It has never been reported in association with familial adenomatous polyposis. We report a case of a 60-year old man with a history of familial adenomatous polyposis, in whom a huge retroperitoneal cyst of 18 \u00d7 17 cm was discovered during routine radiologic evaluation. Because of the impossibility of ruling out the presence of malignancy, surgical cystectomy was performed, associated to a scheduled total colectomy. Pathological examination revealed that the cyst corresponded to an adrenal cavernous hemangioma. Colonic adenomas did not show signs of degeneration. Screening for adenomatous polyposis coli (APC) gene mutation was not carried out. As familial adenomatous polyposis is known to involve a variety of extracolonic manifestations, this finding raises the suspicion of a possible variant of this syndrome including adrenal hemangioma. An extensive study based on a larger patient series with genetic exploration is necessary.<\/jats:p>","DOI":"10.4081\/cp.2016.878","type":"journal-article","created":{"date-parts":[[2016,10,10]],"date-time":"2016-10-10T11:45:20Z","timestamp":1476099920000},"page":"878","source":"Crossref","is-referenced-by-count":4,"title":["Giant Adrenal Cavernous Hemangioma in a Patient with Familial Adenomatous Polyposis"],"prefix":"10.3390","volume":"6","author":[{"given":"Dhouha","family":"Bacha","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abir","family":"Chaabane","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fatma","family":"Khanchel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Saloua","family":"N\u00e9chi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hassen","family":"Touinsi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emna","family":"Chelbi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2016,10,10]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1111\/iju.12957","article-title":"Adrenal cavernous hemangioma associated with myelolipomatous metaplasia","volume":"23","author":"Kinebuchi","year":"2016","journal-title":"Int J Urol"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1186\/1477-7819-7-13","article-title":"A rare coexistence of adrenal cavernous hemangioma with extramedullar hemopoietic tissue: a case report and brief review of the literature","volume":"7","author":"Arkadopoulos","year":"2009","journal-title":"World J Surg Oncol"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1016\/S0300-2896(15)30361-6","article-title":"An unusual cause of adrenal mass in a patient with operable non-small-cell pulmonary carcinoma","volume":"34","author":"Alc\u00e1zar","year":"1998","journal-title":"Arch Bronconeumol"},{"key":"ref4","first-page":"460","article-title":"Simultaneousoccurrence of a cavernous adrenal gland hemangioma and a bile duct-liver carcinoma","volume":"132","author":"Chud\u00e1cek","year":"1980","journal-title":"Rofo"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"2439","DOI":"10.1245\/s10434-008-9981-3","article-title":"Extra-intestinal manifestations of familial adenomatous polyposis","volume":"15","author":"Groen","year":"2008","journal-title":"Ann Surg Oncol"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"961","DOI":"10.1016\/j.purol.2011.02.008","article-title":"L\u2019h\u00e9mangiome caverneux: un incidentalome rare de la surr\u00e9nale","volume":"21","author":"De la vill\u00e9on","year":"2011","journal-title":"Progr Urol"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"624","DOI":"10.1016\/S0003-4266(06)73018-9","article-title":"H\u00e9mangiome surr\u00e9nalien: \u00e0 propos d\u2019un cas","volume":"67","author":"Harzallah","year":"2006","journal-title":"Annal Endocrinol"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1016\/S0022-5347(17)67320-8","article-title":"Hemangioma of the adrenal","volume":"74","author":"Johnson","year":"1955","journal-title":"J Urol"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1590\/1516-3180.2014.1324715","article-title":"Rare cavernous hemangioma of adrenal gland: case report","volume":"132","author":"Wang","year":"2014","journal-title":"Sao Paulo Med J"},{"key":"ref10","series-title":"WHO classification of tumors of Endocrine Organs","article-title":"Tumors World Health Organization, International Agency for Research on Cancer","author":"DeLellis","year":"2004"},{"key":"ref11","first-page":"516","article-title":"Fat containing adrenal cavernous haemangioma: CT and MRI findings","volume":"90","author":"Termote","year":"2007","journal-title":"JBR-BTR"},{"key":"ref12","first-page":"292","article-title":"H\u00e9mangiome surr\u00e9nalien : revue de la litt\u00e9rature","volume":"6","author":"Llado Carbonell","year":"1996","journal-title":"Progr Urol"},{"key":"ref13","first-page":"940","article-title":"Diagnostic et traitement des tumeurs kystiques de la surr\u00e9nale. A propos de 2 observations","volume":"6","author":"Wagner","year":"1996","journal-title":"Progr Urol"},{"key":"ref14","series-title":"WHO classification of tumors of the digestive system","article-title":"International Agency for Research on Cancer","author":"Bosman","year":"2010"},{"key":"ref15","first-page":"185","article-title":"Hereditary hamartomatous polyposis syndromes","volume":"6","author":"Manfredi","year":"2010","journal-title":"Gastroenterol Hepatol (NY)"},{"key":"ref16","first-page":"65","article-title":"Familial adenomatous polyposis associated with multiple adrenal adenomas in a patient with a rare 3\u2019 APC mutation","volume":"36","author":"Kartheuser","year":"1999","journal-title":"J Med Genet"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1034\/j.1600-0455.2003.00039.x","article-title":"Adrenal Adenoma in a patient with Gardner\u2019s Syndrome","volume":"44","author":"Chela\u00effa","year":"2003","journal-title":"Acta Radiol"},{"key":"ref18","doi-asserted-by":"crossref","first-page":"1460","DOI":"10.2214\/ajr.165.6.7484586","article-title":"Adrenal carcinoma in a patient with Gardner\u2019s syndrome: imaging findings","volume":"165","author":"Traill","year":"1995","journal-title":"AJR Am J Roentgenol"},{"key":"ref19","doi-asserted-by":"crossref","first-page":"5133","DOI":"10.1158\/1078-0432.CCR-10-1497","article-title":"Inactivation of the APC gene is constant in adrenocortical tumors from patients with familial adenomatous polyposis but not frequent in sporadic adrenocortical cancers","volume":"16","author":"Gaujoux","year":"2010","journal-title":"Clin Cancer Res"}],"container-title":["Clinics and Practice"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.clinicsandpractice.org\/index.php\/cp\/article\/viewFile\/878\/735","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.mdpi.com\/2039-7283\/6\/3\/878\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,2,10]],"date-time":"2022-02-10T06:38:55Z","timestamp":1644475135000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2039-7283\/6\/3\/878"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,10,10]]},"references-count":19,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2016,8]]}},"alternative-id":["cp.2016.878"],"URL":"https:\/\/doi.org\/10.4081\/cp.2016.878","relation":{},"ISSN":["2039-7283"],"issn-type":[{"value":"2039-7283","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,10,10]]}}}