{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,21]],"date-time":"2025-11-21T17:53:36Z","timestamp":1763747616856},"reference-count":8,"publisher":"MDPI AG","issue":"2","license":[{"start":{"date-parts":[[2017,4,20]],"date-time":"2017-04-20T00:00:00Z","timestamp":1492646400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinics and Practice"],"abstract":"<jats:p>Neuroendocrine tumours are rare in the gynaecologic tract, comprising approximately 2% of all gynaecological tumours. They have an aggressive behaviour and are a diagnostic and clinical challenge, due to their rarity and the lack of standardized therapeutic approaches. There are a few case reports. It is defined as a high-grade carcinoma exhibiting neuroendocrine differentiation. The authors describe the case of a 70-year-old woman, with vulvar neuroendocrine small cell carcinoma after superficial vulvectomy. The patient was submitted to a surgery with wide local excision and adjuvant radiation therapy. A review of the literature on this topic is also presented.<\/jats:p>","DOI":"10.4081\/cp.2017.918","type":"journal-article","created":{"date-parts":[[2017,4,20]],"date-time":"2017-04-20T13:42:55Z","timestamp":1492695775000},"page":"918","source":"Crossref","is-referenced-by-count":5,"title":["Small Cell Carcinoma of the Vulva: Case Report"],"prefix":"10.3390","volume":"7","author":[{"given":"Ana","family":"Correia","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elizabeth","family":"Castelo Branco","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paulo","family":"Correia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marcos","family":"Guimar\u00e3es","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lu\u00eds","family":"S\u00e1","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2017,4,20]]},"reference":[{"key":"ref1","series-title":"Pathology of the female reproductive tract","author":"George","year":"2014"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"877","DOI":"10.1016\/j.gyobfe.2014.07.032","article-title":"Small cell neuroendocrine carcinoma of the vulva","volume":"42","author":"Bouhafa","year":"2014","journal-title":"Gynecol Obstet Fertil"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"410","DOI":"10.1016\/j.ygyno.2014.05.017","article-title":"Small cell carcinoma of the gynecologic tract: a multifaceted spectrum of lesions","volume":"134","author":"Atienza-Amores","year":"2014","journal-title":"Gynecol Oncol"},{"key":"ref4","article-title":"Neuroendocrine tumors of the female reproductive tract: a literature review","volume":"13","author":"Chun","year":"2015","journal-title":"J Pathol Transl Med"},{"key":"ref5","first-page":"128","article-title":"An update of neuroendocrine tumors of the female reproductive system","volume":"31","author":"Kefeli","year":"2015","journal-title":"Turk Patoloji Derg"},{"key":"ref6","series-title":"WHO classification of tumours of female reproductive organs","author":"Kurman","year":"2014"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1016\/j.ygyno.2011.04.011","article-title":"Neuroendocrine tumors of the gynecologic tract: a society of gynecologic oncology (SGO) clinical document","volume":"122","author":"Gardner","year":"2011","journal-title":"Gynecol Oncol"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"572","DOI":"10.1097\/CCO.0b013e3283565ed6","article-title":"The management of small-cell carcinomas of the gynecologic tract","volume":"24","author":"Cohen","year":"2012","journal-title":"Curr Opin Oncol"}],"container-title":["Clinics and Practice"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.clinicsandpractice.org\/index.php\/cp\/article\/viewFile\/918\/799","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.mdpi.com\/2039-7283\/7\/2\/918\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,2,10]],"date-time":"2022-02-10T06:43:30Z","timestamp":1644475410000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2039-7283\/7\/2\/918"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,4,20]]},"references-count":8,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2017,4]]}},"alternative-id":["cp.2017.918"],"URL":"https:\/\/doi.org\/10.4081\/cp.2017.918","relation":{},"ISSN":["2039-7283"],"issn-type":[{"value":"2039-7283","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,4,20]]}}}