{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,24]],"date-time":"2025-08-24T01:38:37Z","timestamp":1755999517783},"reference-count":5,"publisher":"MDPI AG","issue":"1","license":[{"start":{"date-parts":[[2018,1,24]],"date-time":"2018-01-24T00:00:00Z","timestamp":1516752000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinics and Practice"],"abstract":"<jats:p>Chronic kidney disease and acute kidney injury are being increasingly recognized in very elderly patients, aged 80 or more. In cases of suspected glomerulonephritis with or without nephrotic syndrome, the clinical decision-making of whether to obtain a renal biopsy and treat with immunosuppressive therapy should not be based on advanced age alone but take into consideration the patient\u2019s functional status and overall prognosis. Herein, we report a case of an elderly patient with minimal change disease who benefitted from a timely renal biopsy and aggressive immunosuppressive therapy.<\/jats:p>","DOI":"10.4081\/cp.2018.1046","type":"journal-article","created":{"date-parts":[[2018,1,24]],"date-time":"2018-01-24T11:49:44Z","timestamp":1516794584000},"page":"1046","source":"Crossref","is-referenced-by-count":2,"title":["Nephrotic Syndrome in Very Elderly: Should We Treat Aggressively?"],"prefix":"10.3390","volume":"8","author":[{"given":"Abhilash","family":"Koratala","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jogiraju","family":"Tantravahi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2018,1,24]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"525","DOI":"10.2217\/cpr.14.46","article-title":"Chronic kidney disease in the elderly: evaluation and management","volume":"11","author":"Mallappallil","year":"2014","journal-title":"Clin Pract (Lond)"},{"issue":"12","key":"ref2","doi-asserted-by":"crossref","first-page":"2146","DOI":"10.1002\/ccr3.1230","article-title":"An 88-year-old patient with ADPKD: underscoring the importance of risk factor modification","volume":"5","author":"Koratala","year":"2017","journal-title":"Clin Case Rep"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"1073","DOI":"10.2215\/CJN.00990209","article-title":"Renal biopsy in the very elderly","volume":"4","author":"Moutzouris","year":"2009","journal-title":"Clin J Am Soc Nephrol"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"618","DOI":"10.1016\/S0272-6386(04)00944-8","article-title":"Renal biopsy in patients aged 80 years and older","volume":"44","author":"Nair","year":"2004","journal-title":"Am J Kidney Dis"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"2008","DOI":"10.2215\/CJN.04610709","article-title":"Dialysis in late life: benefit or burden","volume":"4","author":"Jassal","year":"2009","journal-title":"Clin J Am Soc Nephrol"}],"container-title":["Clinics and Practice"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.clinicsandpractice.org\/index.php\/cp\/article\/download\/1046\/882","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.clinicsandpractice.org\/index.php\/cp\/article\/download\/1046\/891","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.mdpi.com\/2039-7283\/8\/1\/1046\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,2,10]],"date-time":"2022-02-10T06:51:09Z","timestamp":1644475869000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2039-7283\/8\/1\/1046"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,1,24]]},"references-count":5,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2018,1]]}},"alternative-id":["cp.2018.1046"],"URL":"https:\/\/doi.org\/10.4081\/cp.2018.1046","relation":{},"ISSN":["2039-7283"],"issn-type":[{"value":"2039-7283","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,1,24]]}}}