{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,6]],"date-time":"2025-11-06T12:17:45Z","timestamp":1762431465210},"reference-count":4,"publisher":"MDPI AG","issue":"2","license":[{"start":{"date-parts":[[2018,6,25]],"date-time":"2018-06-25T00:00:00Z","timestamp":1529884800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinics and Practice"],"abstract":"<jats:p>Perioperative management of a neonate with congenital diaphragmatic hernia (CDH) is challenging because of pulmonary hypoplasia, pulmonary hypertension, and respiratory insufficiency. In this report, we present our intra-operative experience in a 4-days old and 3070 grams CDH neonate. He was admitted to neonatal intensive care unit and intubated due to severe respiratory insufficiency. He showed signs of severe pulmonary hypoplasia and his echocardiography revealed a cardiac dextroversion. The patient was relatively stabilized after four days under combined high-frequency oscillatory ventilation (HFOV) and inhaled nitric oxide (iNO). A corrective surgical intervention was sustained with dopamine, dobutamine, fentanyl and midazolam infusions. Ventilator settings were: 9 cmH2O MAP; 15-Hz frequency; 30 cmH2O amplitude and 55% FiO2. Venous-blood gas analysis indicated pH:7.38 pO2:36.2, pCO2:39.2 with SpO2:98%. We believe that HFOV and iNO combination is an effective alternative for the anesthetic management of CDH cases as it provides better gas exchange and less volutrauma.<\/jats:p>","DOI":"10.4081\/cp.2018.1057","type":"journal-article","created":{"date-parts":[[2018,6,25]],"date-time":"2018-06-25T15:25:58Z","timestamp":1529940358000},"page":"1057","source":"Crossref","is-referenced-by-count":4,"title":["Anesthetic Management of a Neonate with Congenital Diaphragmatic Hernia under High-Frequency Oscillatory Ventilation"],"prefix":"10.3390","volume":"8","author":[{"given":"Ipek S.","family":"Edipoglu","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fatma","family":"Celik","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tutku","family":"Ozdogan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Serdar","family":"Comert","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B. Haluk","family":"Guvenc","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2018,6,25]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"667","DOI":"10.1111\/jpc.12508","article-title":"Congenital diaphragmatic hernia","volume":"50","author":"Leeuwen","year":"2014","journal-title":"J Paediatr Child Health"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"1526","DOI":"10.1016\/j.jpedsurg.2007.04.015","article-title":"Retrospective study of 111 cases of congenital diaphragmatic hernia treated with early high-frequency oscillatory ventilation and presurgical stabilization","volume":"42","author":"Migliazza","year":"2007","journal-title":"J Pediatr Surg"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"S91","DOI":"10.4097\/kjae.2014.67.S.S91","article-title":"Use of high-frequency oscillatory ventilation with inhaled nitric oxide in congenital diaphragmatic hernia, omphalocele, and patent ductus arteriosus","volume":"67","author":"Kim","year":"2014","journal-title":"Korean J Anesthesiol"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"1177","DOI":"10.1007\/s00383-012-3184-5","article-title":"Trends in the treatment and outcome of congenital diaphragmatic hernia over the last decade","volume":"28","author":"Garriboli","year":"2012","journal-title":"Pediatr Surg Int"}],"container-title":["Clinics and Practice"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.clinicsandpractice.org\/index.php\/cp\/article\/download\/1057\/910","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.clinicsandpractice.org\/index.php\/cp\/article\/download\/1057\/919","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.mdpi.com\/2039-7283\/8\/2\/1057\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,2,10]],"date-time":"2022-02-10T06:52:39Z","timestamp":1644475959000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2039-7283\/8\/2\/1057"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,6,25]]},"references-count":4,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2018,3]]}},"alternative-id":["cp.2018.1057"],"URL":"https:\/\/doi.org\/10.4081\/cp.2018.1057","relation":{},"ISSN":["2039-7283"],"issn-type":[{"value":"2039-7283","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,6,25]]}}}