{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,5]],"date-time":"2026-02-05T13:52:07Z","timestamp":1770299527353,"version":"3.49.0"},"reference-count":19,"publisher":"MDPI AG","issue":"1","license":[{"start":{"date-parts":[[2019,2,20]],"date-time":"2019-02-20T00:00:00Z","timestamp":1550620800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinics and Practice"],"abstract":"<jats:p>In adults, intestinal malrotation is an oligosymptomatic entity that is occasionally discovered during the course of diagnostic studies for other causes. In the case described herein, intestinal malrotation was discovered during investigation for cholelithiasis and acute cholecystitis. Malrotation may occur due to alterations in the asymmetric cellular dynamics of the mesentery responsible for intestinal shortening and unilateral retraction, this may occur as a secondary event following alterations in the expression of homeodomain transcription factors. The incidental finding of asymptomatic intestinal malrotation in adults does not preclude its surgical treatment. However, when intestinal malrotation is associated with cholecystitis, due to cholelithiasis, it is advisable, to first treat the cholecystitis conservatively, in our case, and then perform partial adhesiolysis of the Ladd bands that hinder access to the cystic area and carry out cholecystectomy by elective laparoscopy.<\/jats:p>","DOI":"10.4081\/cp.2019.1091","type":"journal-article","created":{"date-parts":[[2019,2,20]],"date-time":"2019-02-20T19:40:49Z","timestamp":1550691649000},"page":"1091","source":"Crossref","is-referenced-by-count":1,"title":["Delayed Laparoscopic Cholecystectomy in a Case of Acute Cholecystitis and Intestinal Malrotation Type I"],"prefix":"10.3390","volume":"9","author":[{"given":"Ana","family":"Arias","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carlos","family":"Ordieres","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adrian","family":"Huergo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marta","family":"Posadilla","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pedro","family":"Amor","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ana","family":"Milla","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2019,2,20]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"769","DOI":"10.1007\/s00383-010-2622-5","article-title":"Review of genetic factors in intestinal malrotation","volume":"26","author":"Martin","year":"2010","journal-title":"Pediatr Surg Int"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"628","DOI":"10.1016\/j.jamcollsurg.2004.04.024","article-title":"Intestinal malrotation- not just the pediatric surgeon \u0313s problem","volume":"199","author":"Kapfer","year":"2004","journal-title":"J Am Coll Surg"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"1219","DOI":"10.1148\/radiographics.19.5.g99se041219","article-title":"Congenital anomalies of the small intestine, colon, and rectum","volume":"19","author":"Berrocal","year":"1999","journal-title":"Radiographics"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"837","DOI":"10.1007\/s00247-004-1279-4","article-title":"Disorders of intestinal rotation and fixation, malrotation","volume":"34","author":"Strouse","year":"2004","journal-title":"Pediatr Radiol"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/j.amjsurg.2005.10.002","article-title":"The optimal management of malrotation diagnosed after infancy: a decision analysis","volume":"191","author":"Malek","year":"2006","journal-title":"Am J Surg"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1002\/jhbp.516","article-title":"Tokyo guidelines 2018: flowchart for the management of acute cholecystitis","volume":"25","author":"Okamoto","year":"2018","journal-title":"J Hepatobil Pancreas Sci"},{"key":"ref7","first-page":"245","volume":"5","author":"Husberg","year":"2016","journal-title":"Congenital intestinal malrotation in adolescent and adult patients: a 12-year clinical and radiological survey, Springerplus"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/j.rx.2014.07.007","article-title":"Intestinal maltoration-volvulus: imaging findings","volume":"57","author":"Ballesteros G\u00f3miz","year":"2015","journal-title":"Radiologia"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1097\/00000658-195409000-00013","article-title":"Embryology and pathology of the intestinal tract: presentation of 40 cases of malrotation","volume":"140","author":"Snyder","year":"1954","journal-title":"Ann Surg"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1016\/j.devcel.2008.05.001","article-title":"The chirality of gut rotation derives from left-right asymmetric changes in the architecture of the dorsal mesentery","volume":"15","author":"Davis","year":"2008","journal-title":"Dev Cell"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1016\/j.devcel.2013.08.018","article-title":"Your gut is right to turn left","volume":"26","author":"Klezovitch","year":"2013","journal-title":"Dev Cell"},{"key":"ref12","first-page":"21","article-title":"Control of stomach smooth muscle development and intestinal rotation by transcription factor BARX1","volume":"405","author":"Jayewickreme","year":"2015","journal-title":"Dev Cell"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"714","DOI":"10.1038\/nature21703","article-title":"Somatic mutations reveal asymmetric cellular dynamics in the early embryo","volume":"543","author":"Ju","year":"2017","journal-title":"Nature"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1186\/s40064-016-1842-0","article-title":"Congenital intestinal malrotation in adolescent and adult patients: a 12-year clinical and radiological survey","volume":"5","author":"Husberg","year":"2016","journal-title":"Springerplus"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1007\/s12262-015-1320-x","article-title":"Malrotation of the intestine in adult and colorectal cancer","volume":"77","author":"Ray","year":"2015","journal-title":"Indian J Surg"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"837","DOI":"10.1007\/s00247-004-1279-4","article-title":"Disorders of intestinal rotation and fixation (\u201cmalrotation\u201d)","volume":"34","author":"Strouse","year":"2004","journal-title":"Pediatr Radiol"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"705","DOI":"10.1056\/NEJM193610152151604","article-title":"Surgical disease of the alimentary tract in infants","volume":"215","author":"Ladd","year":"1936","journal-title":"N Engl J Med"},{"key":"ref18","doi-asserted-by":"crossref","first-page":"386","DOI":"10.1016\/j.surg.2010.07.004","article-title":"Intestinal malrotation: varied clinical presentation from infancy through adulthood","volume":"149","author":"Nehra","year":"2011","journal-title":"Surgery"},{"key":"ref19","first-page":"239","article-title":"The presentation of malrotation of the intestines in adults","volume":"72","author":"Kern","year":"1990","journal-title":"Ann R Coll Surg Engl"}],"container-title":["Clinics and Practice"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.clinicsandpractice.org\/index.php\/cp\/article\/download\/1091\/951","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.clinicsandpractice.org\/index.php\/cp\/article\/download\/1091\/964","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.mdpi.com\/2039-7283\/9\/1\/1091\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,2,10]],"date-time":"2022-02-10T06:55:44Z","timestamp":1644476144000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2039-7283\/9\/1\/1091"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,2,20]]},"references-count":19,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2019,1]]}},"alternative-id":["cp.2019.1091"],"URL":"https:\/\/doi.org\/10.4081\/cp.2019.1091","relation":{},"ISSN":["2039-7283"],"issn-type":[{"value":"2039-7283","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,2,20]]}}}