{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,4,5]],"date-time":"2022-04-05T22:26:02Z","timestamp":1649197562815},"reference-count":11,"publisher":"MDPI AG","issue":"3","license":[{"start":{"date-parts":[[2019,8,9]],"date-time":"2019-08-09T00:00:00Z","timestamp":1565308800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinics and Practice"],"abstract":"<jats:p>Primary pulmonary histoplasmosis is found worldwide, and is particularly endemic in some areas of the North America, usually those surrounding the Ohio and Mississippi river valleys. It is not common in the East Coast of the United States, and is in fact, reportable in Pennsylvania. It has been rarely described in immunocompetent individuals residing in a non-endemic region. We present a case of a previously healthy middle-aged male, a Pennsylvania resident, who presented with mid-sternal chest discomfort, fatigue, chills and mild shortness of breath, and was diagnosed with primary pulmonary histoplasmosis.<\/jats:p>","DOI":"10.4081\/cp.2019.1141","type":"journal-article","created":{"date-parts":[[2019,8,9]],"date-time":"2019-08-09T20:53:20Z","timestamp":1565384000000},"page":"1141","source":"Crossref","is-referenced-by-count":0,"title":["An Unusual Infection in an Immunocompetent Male from a Non-Endemic Area: Lessons from a Vacation"],"prefix":"10.3390","volume":"9","author":[{"given":"Ritesh","family":"Neupane","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Munish","family":"Sharma","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Divakar","family":"Sharma","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rajeev","family":"Thachil","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mahesh","family":"Krishnamurthy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gerald","family":"Lowman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2019,8,9]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1378\/chest.29.6.649","article-title":"Geographic variation in the prevalence of histoplasmin sensitivity","volume":"29","author":"Manos","year":"1956","journal-title":"Dis Chest"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"1664","DOI":"10.3201\/eid1709.101987","article-title":"Geographic distribution of endemic fungal infections among older persons, United States","volume":"17","author":"Baddley","year":"2011","journal-title":"Emerg Infect Dis"},{"key":"ref3","first-page":"365","article-title":"The changing face of mycoses in patients with HIV\/AIDS","volume":"11","author":"Haddad","year":"2001","journal-title":"AIDS Read"},{"key":"ref4","first-page":"1349","article-title":"Outbreak of histoplasmosis among travelers returning from El Salvador-Pennsylvania and Virginia, 2008","volume":"57","year":"2008","journal-title":"MMWR"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"1878","DOI":"10.1086\/648421","article-title":"Diagnosis of acute pulmonary histoplasmosis by antigen detection","volume":"49","author":"Swartzentruber","year":"2009","journal-title":"Clin Infect Dis"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1007\/s11908-007-0071-7","article-title":"Nonculture diagnostic methods for invasive fungal infections","volume":"9","author":"Wheat","year":"2007","journal-title":"Curr Infect Dis Rep"},{"key":"ref7","first-page":"63","article-title":"Histoplasmosis mimicking primary lung cancer or pulmonary metastases","volume":"39","author":"Bello","year":"2013","journal-title":"J Bras Pneumol"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1590\/S0037-86822011000100007","article-title":"Oropharyngeal histoplasmosis: report of eleven cases and review of the literature","volume":"44","author":"Antonello","year":"2011","journal-title":"Rev Soc Bras Med Trop"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1097\/00005792-197611000-00001","article-title":"Chronic pulmonary histoplasmosis","volume":"55","author":"Goodwin","year":"1976","journal-title":"Medicine (Baltimore)"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"105","DOI":"10.7326\/0003-4819-137-2-200207160-00008","article-title":"Safety and efficacy of liposomal amphotericin B compared with conventional amphotericin B for induction therapy of histoplasmosis in patients with AIDS","volume":"137","author":"Johnson","year":"2002","journal-title":"Ann Intern Med"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1016\/0002-9343(92)90575-V","article-title":"Itraconazole therapy for blastomycosis and histoplasmosis. NIAID Mycoses Study Group","volume":"93","author":"Dismukes","year":"1992","journal-title":"Am J Med"}],"container-title":["Clinics and Practice"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.clinicsandpractice.org\/index.php\/cp\/article\/download\/1141\/990","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.clinicsandpractice.org\/index.php\/cp\/article\/download\/1141\/1001","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.mdpi.com\/2039-7283\/9\/3\/1141\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,2,10]],"date-time":"2022-02-10T07:00:12Z","timestamp":1644476412000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2039-7283\/9\/3\/1141"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,8,9]]},"references-count":11,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2019,8]]}},"alternative-id":["cp.2019.1141"],"URL":"https:\/\/doi.org\/10.4081\/cp.2019.1141","relation":{},"ISSN":["2039-7283"],"issn-type":[{"value":"2039-7283","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,8,9]]}}}