{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,15]],"date-time":"2025-07-15T03:39:56Z","timestamp":1752550796485},"reference-count":11,"publisher":"MDPI AG","issue":"2","license":[{"start":{"date-parts":[[2020,6,22]],"date-time":"2020-06-22T00:00:00Z","timestamp":1592784000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinics and Practice"],"abstract":"<jats:p>Brunner\u2019s gland hyperplasia (BGH) is an unusual entity that presents with large duodenal polyp or mass and rarely causes gastrointestinal bleeding. It is usually asymptomatic and often an incidental finding during the esophagoduodenoscopy (EGD). However, most of the cases are benign. We encounter a 40 years old man who presented in Emergency Room with melena. EGD revealed solitary, large duodenal polyp in second part of duodenum and later histopathological findings were consistent with BGH.<\/jats:p>","DOI":"10.4081\/cp.2020.1267","type":"journal-article","created":{"date-parts":[[2020,6,22]],"date-time":"2020-06-22T14:19:34Z","timestamp":1592835574000},"page":"1267","source":"Crossref","is-referenced-by-count":2,"title":["Brunner\u2019s Gland Hyperplasia: A Rare Cause of Gastrointestinal Bleeding"],"prefix":"10.3390","volume":"10","author":[{"given":"Lubna","family":"Kamani","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ravi","family":"Raj","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rabia","family":"Ali","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Faisal","family":"Siddiqi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2020,6,22]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"419","DOI":"10.4318\/tjg.2011.0264","article-title":"Brunner\u2019s gland hyperplasia: an unusual cause of gastrointestinal bleeding","volume":"22","author":"Malik","year":"2011","journal-title":"Turk J Gastroenterol"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1007\/BF01888437","article-title":"\u00dcberWucherungen der BrunnerschenDr\u00fcsen","volume":"293","author":"Feyrter","year":"1934","journal-title":"Virchows Arch"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1159\/000355881","article-title":"A case of adenocarcinoma of the duodenum arising from Brunner\u2019s gland","volume":"7","author":"Kamei","year":"2013","journal-title":"Case Rep Gastroenterol"},{"key":"ref4","first-page":"81","article-title":"Diffuse nodular hyperplasia of Brunner\u2019s gland presenting as upper gastrointestinal hemorrhage","volume":"49","author":"Chattopadhyay","year":"2008","journal-title":"Singapore Med J"},{"key":"ref5","first-page":"38","article-title":"Brunner\u2019s gland hyperplasia at the ampulla of Vater","volume":"52","author":"Janes","year":"2006","journal-title":"J Postgrad Med"},{"key":"ref6","first-page":"128","article-title":"Biliary obstruction and pancreatitis caused by diffuse nodular hyperplasia of Brunner\u2019s gland","volume":"40","author":"Kibria","year":"2009","journal-title":"J GastrointestCanc"},{"key":"ref7","first-page":"121","article-title":"Brunner\u2019s gland hamartoma and hyperplasia","volume":"31","author":"Kini","year":"2010","journal-title":"Trop Gastroenterol"},{"key":"ref8","first-page":"7565","article-title":"Bruner\u2019s gland adenoma of duodenum: report of two cases","volume":"8","author":"Lu","year":"2015","journal-title":"Int J Clin Exp Pathol"},{"key":"ref9","article-title":"Junqueira\u2019s basic histology: text & atlas, 13th ed. Chapter 15 - Digestive tract","author":"Mescher","year":"2013"},{"key":"ref10","first-page":"46","article-title":"Pathologic observations of the duodenum of 615 consecutive duodenal specimens: benign lesions","volume":"5","author":"Terada","year":"2012","journal-title":"Int J Clin Exp Pathol"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"956","DOI":"10.1055\/s-2002-35849","article-title":"Endosonographic features of Brunner\u2019s gland hamartomas which were subsequently resected endoscopically","volume":"34","author":"Hizawa","year":"2002","journal-title":"Endoscopy"}],"container-title":["Clinics and Practice"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.clinicsandpractice.org\/index.php\/cp\/article\/download\/1267\/1047","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.mdpi.com\/2039-7283\/10\/2\/1267\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,2,10]],"date-time":"2022-02-10T07:05:08Z","timestamp":1644476708000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2039-7283\/10\/2\/1267"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,6,22]]},"references-count":11,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2020,5]]}},"alternative-id":["cp.2020.1267"],"URL":"https:\/\/doi.org\/10.4081\/cp.2020.1267","relation":{},"ISSN":["2039-7283"],"issn-type":[{"value":"2039-7283","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,6,22]]}}}