{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,17]],"date-time":"2026-04-17T10:13:17Z","timestamp":1776420797429,"version":"3.51.2"},"reference-count":19,"publisher":"PAGEPress Publications","issue":"3","license":[{"start":{"date-parts":[[2022,3,22]],"date-time":"2022-03-22T00:00:00Z","timestamp":1647907200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Dermatol Reports"],"abstract":"<jats:p>Late-onset focal dermal elastosis is a rare cutaneous condition classified as an increased dermal elastic tissue disorder. It is distinguished clinically by multiple papules with a preference for the neck and other flexures, as well as histologically by focally increased elastic fibers in the reticular dermis. Several elastic tissue disorders in the skin have a similar clinical presentation. The distinction between late-onset focal dermal elastosis and other pseudoxanthoma elasticum mimickers is critical because they are not associated with systemic lesions. We present a case of late-onset focal dermal elastosis and conduct a literature review on this unusual condition.<\/jats:p>","DOI":"10.4081\/dr.2022.9337","type":"journal-article","created":{"date-parts":[[2022,3,22]],"date-time":"2022-03-22T15:55:07Z","timestamp":1647964507000},"source":"Crossref","is-referenced-by-count":2,"title":["Late-onset focal dermal elastosis: Report of a case and review of the literature"],"prefix":"10.4081","volume":"14","author":[{"given":"Fabrizio","family":"Fantini","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emanuele","family":"Dainese","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sebastiano","family":"Recalcati","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2549","published-online":{"date-parts":[[2022,3,22]]},"reference":[{"key":"6861","doi-asserted-by":"crossref","unstructured":"Tajima S, Shimizu K, Izumi T, et al. Late-onset focal dermal elastosis: clinical and histological features. Br J Dermatol 1995;133:303-5.","DOI":"10.1111\/j.1365-2133.1995.tb02634.x"},{"key":"6862","doi-asserted-by":"crossref","unstructured":"Lewis KG, Bercovitch L, Dill SW, Robinson-Bostom L. Acquired disorders of elastic tissue: part I. Increased elastic tissue and solar elastotic syndromes. J Am Acad Dermatol 2004;51:1-21.","DOI":"10.1016\/j.jaad.2004.03.013"},{"key":"6863","doi-asserted-by":"crossref","unstructured":"Chassaing N, Martin L, Calvas P, et al. Pseudoxanthoma elasticum: a clinical, pathophysiological and genetic update including 11 novel ABCC6 mutations. J Med Genet 2005;42:881-92.","DOI":"10.1136\/jmg.2004.030171"},{"key":"6864","doi-asserted-by":"crossref","unstructured":"Rongioletti F, Rebora A. Fibroelastolytic patterns of intrinsic skin aging: pseudoxanthoma-elasticum-like papillary dermal elastolysis and white fibrous papulosis of the neck. Dermatology 1995;191:19-24.","DOI":"10.1159\/000246478"},{"key":"6865","doi-asserted-by":"crossref","unstructured":"Wang AR, Lewis K, Lewis M, Robinson-Bostom L. Papillary dermal elastosis: a unique elastic tissue disorder or an unusual manifestation of pseudoxanthoma elasticum-like papillary dermal elastolysis? J Cutan Pathol 2009;36:1010-3.","DOI":"10.1111\/j.1600-0560.2008.01183.x"},{"key":"6866","doi-asserted-by":"crossref","unstructured":"Tajima S, Inazumi T, Kobayashi T. A case of acrogeria associated with late-onset focal dermal elastosis. Dermatology 1996;192:264-8.","DOI":"10.1159\/000246381"},{"key":"6867","doi-asserted-by":"crossref","unstructured":"Camacho D, Machan S, Pielasinski U, et al. Familial acral localized late-onset focal dermal elastosis. Am J Dermatopathol 2012;34:310-4.","DOI":"10.1097\/DAD.0b013e31823adf2e"},{"key":"6868","doi-asserted-by":"crossref","unstructured":"Wang AR, Fonder MA, Telang GH, et al. Late-onset focal dermal elastosis: an uncommon mimicker of pseudoxanthoma elasticum. J Cutan Pathol 2012;39:957-61.","DOI":"10.1111\/j.1600-0560.2012.01979.x"},{"key":"6869","doi-asserted-by":"crossref","unstructured":"Knapp M, Carpenter CE, Shea K, et al. Focal Dermal Elastosis: A Proposed Update to the Nomenclature. Am J Dermatopathol 2020;42:774-5.","DOI":"10.1097\/DAD.0000000000001683"},{"key":"6870","doi-asserted-by":"crossref","unstructured":"Tajima S, Tanaka N, Ohnishi Y et al. Analysis of elastin metabolism in patients with late-onset focal dermal elastosis. Acta Derm Venereol 1999;79:285-7.","DOI":"10.1080\/000155599750010670"},{"key":"6871","doi-asserted-by":"crossref","unstructured":"Hanami Y, Nakamura T, Yamamoto T. Case of late-onset focal dermal elastosis. J Dermatol 2018;45:e339-e40.","DOI":"10.1111\/1346-8138.14472"},{"key":"6872","doi-asserted-by":"crossref","unstructured":"Limas C. Late onset focal dermal elastosis: a distinct clinicopathologic entity? Am J Dermatopathol 1999;21:381-3.","DOI":"10.1097\/00000372-199908000-00013"},{"key":"6873","doi-asserted-by":"crossref","unstructured":"Kossard S. Pseudoxanthoma-like late-onset focal dermal elastosis. Australas J Dermatol 2005;46:47-50.","DOI":"10.1111\/j.1440-0960.2004.00141.x"},{"key":"6874","unstructured":"Higgins HJ, Whitworth MW. Late-onset focal dermal elastosis: a case report and review of the literature. Cutis 2010;85:195-7."},{"key":"6875","doi-asserted-by":"crossref","unstructured":"Tian S, Chen Z. Late-onset focal dermal elastosis. Eur J Dermatol 2012;22:399-400.","DOI":"10.1684\/ejd.2012.1664"},{"key":"6876","unstructured":"Jansen MHE, Lijnen RLP, Lohman BGPM. Pseudoxanthoma elasticum en late onset focal dermal elastosis. Nederlands Tijdschrift voor Dermatologie en Venereologie 2014;24:652-5."},{"key":"6877","unstructured":"Chappell J , Kozel J , Yadira Hurley M , Vidal . A Yellow Papular Eruption on the Arms, Legs, and Neck: A Rare Masquerader. 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