{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T12:08:54Z","timestamp":1747224534362,"version":"3.40.5"},"reference-count":14,"publisher":"PAGEPress Publications","license":[{"start":{"date-parts":[[2023,8,10]],"date-time":"2023-08-10T00:00:00Z","timestamp":1691625600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Dermatol Reports"],"abstract":"<jats:p>Bleomycin, an antineoplastic antibiotic that inhibits DNA synthesis, is used to treat various malignant tumours such as Hodgkin's lymphoma, squamous cell carcinoma, and germ cell tumors. Flagellate erythema is a rare rash with a linear pattern that has been observed in association with bleomycin treatment. Herein, we present a 43-year-old patient with metastatic testicular cell neoplasms who developed a whiplash rash during treatment with a chemotherapy regimen that included bleomycin. A typical case of bleomycin-related flagellate dermatitis has been diagnosed and the main features of this characteristic adverse drug event are briefly discussed.<\/jats:p>","DOI":"10.4081\/dr.2023.9761","type":"journal-article","created":{"date-parts":[[2023,8,10]],"date-time":"2023-08-10T13:49:04Z","timestamp":1691675344000},"source":"Crossref","is-referenced-by-count":1,"title":["Flagellate dermatitis in a patient with testicular germ cell neoplasia on bleomycin"],"prefix":"10.4081","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3609-913X","authenticated-orcid":false,"given":"Konstantina","family":"Mavridou","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-3818-803X","authenticated-orcid":false,"given":"Aggeliki","family":"Karakasi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8633-7135","authenticated-orcid":false,"given":"Evangeli","family":"Lampri","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"George","family":"Gaitanis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0252-8314","authenticated-orcid":false,"given":"Ioannis D","family":"Bassukas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2549","published-online":{"date-parts":[[2023,8,10]]},"reference":[{"key":"10912","doi-asserted-by":"crossref","unstructured":"Indrastuti N, Mariyani S, Meidiyanti P. Flagellate dermatitis in bleomycin chemotherapy: a causality? BMJ Case Rep 2022;15:e249704.","DOI":"10.1136\/bcr-2022-249704"},{"key":"10913","unstructured":"Moulin MMJ, Fi\u00e8re B, Beyvin A. Cutaneous pigmentation caused by bleomycin. Bull Soc Fr Dermatol Syphiligr 1970;293-6."},{"key":"10914","doi-asserted-by":"crossref","unstructured":"Turan Erkek E, Karaali CN, Y\u0131lmaz G, G\u00fclt\u00fcrk E. Bleomycin-Induced Flagellate Dermatitis. Turk J Haematol 2019;36:138-40.","DOI":"10.4274\/tjh.galenos.2019.2018.0317"},{"key":"10915","doi-asserted-by":"crossref","unstructured":"Maruthappu T, Hader Z. A characteristic rash caused by Shiitake mushrooms \u2013 An emerging concern?. Clin Case Rep 2021;9:e04181.","DOI":"10.1002\/ccr3.4181"},{"key":"10916","doi-asserted-by":"crossref","unstructured":"Rehan HS, Chopra D, Kakkar AK. Physician's guide to pharmacovigilance: terminology and causality assessment. 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J Egypt Natl Canc Inst 2016;28:129-32.","DOI":"10.1016\/j.jnci.2016.04.002"},{"key":"10921","doi-asserted-by":"crossref","unstructured":"Fyfe AJ, McKay P. Toxicities associated with bleomycin. J R Coll Physicians Edinb 2010;40:213-5.","DOI":"10.4997\/JRCPE.2010.306"},{"key":"10922","doi-asserted-by":"crossref","unstructured":"Cullingham K, Kost G. A case of bleomycin-induced flagellate dermatitis: A case report. SAGE Open Med Case Rep 2021;9:2050313X211039476.","DOI":"10.1177\/2050313X211039476"},{"key":"10923","doi-asserted-by":"crossref","unstructured":"Chen Y-B, Rahemtullah A, Breeden E, Hochberg EP. Bleomycin-induced flagellate erythema. J Clin Oncol 2007;25:898-900.","DOI":"10.1200\/JCO.2006.09.7691"},{"key":"10924","doi-asserted-by":"crossref","unstructured":"Adjade G, El Fadli M, Afani L, Belbaraka R. Bleomycin-Induced flagellate erythema in a patient with germ cell tumor. 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