{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,6]],"date-time":"2025-11-06T16:11:22Z","timestamp":1762445482666,"version":"3.40.5"},"reference-count":10,"publisher":"PAGEPress Publications","license":[{"start":{"date-parts":[[2024,4,19]],"date-time":"2024-04-19T00:00:00Z","timestamp":1713484800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Dermatol Reports"],"abstract":"<jats:p>Imiquimod 5% cream is an approved treatment for actinic keratoses, superficial basal cell carcinomas and anogenital warts. Severe systemic side effects associated to imiquimod 5% cream are rare, although few cases of erythema multiforme and Stevens-Johnson syndrome have been described. We present a case of Stevens-Johnson syndrome associated to topical treatment with imiquimod of two superficial basal cell carcinomas.<\/jats:p>","DOI":"10.4081\/dr.2024.9930","type":"journal-article","created":{"date-parts":[[2024,4,19]],"date-time":"2024-04-19T08:09:03Z","timestamp":1713514143000},"source":"Crossref","is-referenced-by-count":2,"title":["Stevens-Johnson induced by imiquimod 5% cream: a case report"],"prefix":"10.4081","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5469-4517","authenticated-orcid":false,"given":"Ilaria","family":"Trave","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0151-3126","authenticated-orcid":false,"given":"Ilaria","family":"Salvi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Claudia","family":"Micalizzi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7184-7888","authenticated-orcid":false,"given":"Riccardo","family":"Castelli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6622-2226","authenticated-orcid":false,"given":"Aurora","family":"Parodi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emanuele","family":"Cozzani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2549","published-online":{"date-parts":[[2024,4,19]]},"reference":[{"key":"15865","doi-asserted-by":"crossref","unstructured":"Cantisani C, Lazic T, Richetta AG, Clerico R, Mattozzi C, Calvieri S. Imiquimod 5% cream use in dermatology, side effects and recent patents. Recent Pat Inflamm Allergy Drug Discov. 2012 Jan;6:65-9.","DOI":"10.2174\/187221312798889301"},{"key":"15866","unstructured":"Nanda J, Bermudez R. Imiquimod. 2022 Jul 12. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2022."},{"key":"15867","unstructured":"Camacho Molina A, Alarc\u00f3n Manoja E, Corzo Gilabert JR, Garc\u00eda Gil D. Erythema multiforme induced by topical imiquimod. Emergencias. 2020;32:219."},{"key":"15868","doi-asserted-by":"crossref","unstructured":"Frantz R, Huang S, Are A, Motaparthi K. Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis: A Review of Diagnosis and Management. Medicina (Kaunas). 2021 Aug 28;57(9):895. doi: 10.3390\/medicina57090895. PMID: 34577817; PMCID: PMC8472007.","DOI":"10.3390\/medicina57090895"},{"key":"15869","doi-asserted-by":"crossref","unstructured":"Bastuji-Garin S, Rzany B, Stern RS, Shear NH, Naldi L, Roujeau JC. Clinical classification of cases of toxic epidermal necrolysis, Stevens-Johnson syndrome, and erythema multiforme. Arch Dermatol. 1993 Jan;129(1):92-6.","DOI":"10.1001\/archderm.129.1.92"},{"key":"15870","doi-asserted-by":"crossref","unstructured":"Shaw B, Madden M, Crespo A, Madruga M, Carlan SJ. A Rare Case of Severe Stevens-Johnson Syndrome Triggered by Topical Ofloxacin. Am J Case Rep. 2023 Nov 12;24:e941992. doi: 10.12659\/AJCR.941992. PMID: 37952083; PMCID: PMC10654684.","DOI":"10.12659\/AJCR.941992"},{"key":"15871","doi-asserted-by":"crossref","unstructured":"Das A, Banerjee A, Tripathy K. Topical moxifloxacin-induced Stevens-Johnson syndrome. J Cataract Refract Surg. 2017 Jun;43(6):860-861. doi: 10.1016\/j.jcrs.2017.03.043. PMID: 28732631.","DOI":"10.1016\/j.jcrs.2017.03.043"},{"key":"15872","doi-asserted-by":"crossref","unstructured":"N\u00fa\u00f1ez Ortiz A, Trigo Salado C, de la Cruz Ram\u00edrez MD, Herrera Justiniano JM, Leo Carnerero E. Topical mesalazine as a cause of Stevens-Johnson syndrome. Rev Esp Enferm Dig. 2018 Nov;110(11):736-738. doi: 10.17235\/reed.2018.5429\/2017. PMID: 29931986.","DOI":"10.17235\/reed.2018.5429\/2017"},{"key":"15873","doi-asserted-by":"crossref","unstructured":"Leitner C. Topical imiquimod\u2014Be aware of the unexpected. JAAD. 2016;74:AB223.","DOI":"10.1016\/j.jaad.2016.02.877"},{"key":"15874","doi-asserted-by":"crossref","unstructured":"Tedman A, Malla U, Vasanthakumar L, Buzacott K, Banney L. Stevens-Johnson syndrome due to topical imiquimod 5%. Aust J Gen Pract. 2020;49:662-664.","DOI":"10.31128\/AJGP-11-19-5145"}],"container-title":["Dermatology Reports"],"original-title":[],"link":[{"URL":"https:\/\/www.pagepress.org\/journals\/dr\/article\/download\/9930\/9376","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.pagepress.org\/journals\/dr\/article\/download\/9930\/9376","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,4,19]],"date-time":"2024-04-19T08:09:13Z","timestamp":1713514153000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.pagepress.org\/journals\/dr\/article\/view\/9930"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,4,19]]},"references-count":10,"URL":"https:\/\/doi.org\/10.4081\/dr.2024.9930","relation":{},"ISSN":["2036-7406","2036-7392"],"issn-type":[{"type":"electronic","value":"2036-7406"},{"type":"print","value":"2036-7392"}],"subject":[],"published":{"date-parts":[[2024,4,19]]}}}