{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,6]],"date-time":"2025-11-06T12:34:58Z","timestamp":1762432498952,"version":"3.44.0"},"reference-count":11,"publisher":"PAGEPress Publications","issue":"3","license":[{"start":{"date-parts":[[2025,1,20]],"date-time":"2025-01-20T00:00:00Z","timestamp":1737331200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Dermatol Reports"],"abstract":"<jats:p>Pityriasis rosea (PR) is an exanthematous disease associated with the endogenous systemic reactivation of human herpesvirus (HHV)-6 and\/or HHV-7. Variants of PR characterized by atypical lesion morphology, eruption course, and severe symptoms have already been described, but their prevalence is probably underestimated. We report herein two patients suffering from anorexia nervosa (AN) who developed a very rare form of purpuric PR. So far, no cases of PR in AN patients have been reported in the literature.<\/jats:p>","DOI":"10.4081\/dr.2025.10053","type":"journal-article","created":{"date-parts":[[2025,1,20]],"date-time":"2025-01-20T09:33:57Z","timestamp":1737365637000},"source":"Crossref","is-referenced-by-count":1,"title":["Purpuric pityriasis rosea in patients with anorexia nervosa"],"prefix":"10.4081","volume":"17","author":[{"given":"Giulia","family":"Ciccarese","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antonio","family":"Guadagno","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Astrid","family":"Herzum","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Valentina","family":"Amicarelli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francesco","family":"Drago","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2549","published-online":{"date-parts":[[2025,1,20]]},"reference":[{"doi-asserted-by":"crossref","unstructured":"Drago F, Ciccarese G, Merlo G, et al. Oral and cutaneous manifestations of viral and bacterial infections: Not only COVID-19 disease. Clin Dermatol 2021;39:384-404.","key":"23150","DOI":"10.1016\/j.clindermatol.2021.01.021"},{"doi-asserted-by":"crossref","unstructured":"Drago F, Ciccarese G, Broccolo F, et al. The Role of Cytokines, Chemokines, and Growth Factors in the Pathogenesis of Pityriasis Rosea. Mediators Inflamm 2015;2015:438963.","key":"23151","DOI":"10.1155\/2015\/438963"},{"doi-asserted-by":"crossref","unstructured":"Hartman MS. Pityriasis rosea. Arch Dermatol 1944;50:201.","key":"23152","DOI":"10.1001\/archderm.1944.01510150053013"},{"doi-asserted-by":"crossref","unstructured":"Daze RP, Dorton D. An Atypical Presentation of Pityriasis Rosea Localized to the Extremities. Cureus 2020;12:e9765.","key":"23153","DOI":"10.7759\/cureus.9765"},{"doi-asserted-by":"crossref","unstructured":"Tamer F, Sarifakioglu E, Orenay OM, Yildirim U. Persistent and Generalized Purpuric Lesions in an Adolescent: A Rare Atypical Form of Pityriasis Rosea. Indian Dermatol Online J 2017;8:217-8.","key":"23154","DOI":"10.4103\/2229-5178.206112"},{"doi-asserted-by":"crossref","unstructured":"Kilinc F, Akbas A, Sener S, Akta\u015f A. Atypical pityriasis rosea: clinical evaluation of 27 patients. Cutan Ocul Toxicol 2017;36:157-62.","key":"23155","DOI":"10.1080\/15569527.2016.1225217"},{"doi-asserted-by":"crossref","unstructured":"Allende LM, Corell A, Manzanares J, et al. Immunodeficiency associated with anorexia nervosa is secondary and improves after refeeding. Immunology 1998;94:543-51.","key":"23156","DOI":"10.1046\/j.1365-2567.1998.00548.x"},{"doi-asserted-by":"crossref","unstructured":"Hebebrand J, Antel J, von Piechowski L, et al. Case report: Rapid improvements of anorexia nervosa and probable myalgic encephalomyelitis\/chronic fatigue syndrome upon metreleptin treatment during two dosing episodes. Front Psychiatry 2023;14:1267495.","key":"23157","DOI":"10.3389\/fpsyt.2023.1267495"},{"doi-asserted-by":"crossref","unstructured":"Ciccarese G, Trave I, Herzum A, et al. Dermatological manifestations of Epstein-Barr virus systemic infection: a case report and literature review. Int J Dermatol 2020;59:1202-9.","key":"23158","DOI":"10.1111\/ijd.14887"},{"doi-asserted-by":"crossref","unstructured":"S\u0142otwi\u0144ska SM, S\u0142otwi\u0144ski R. Immune disorders in anorexia. Cent Eur J Immunol 2017;42:294-300.","key":"23159","DOI":"10.5114\/ceji.2017.70973"},{"doi-asserted-by":"crossref","unstructured":"V\u00edctor VM, Rovira-Llopis S, Saiz-Alarc\u00f3n V, et al. Involvement of leucocyte\/endothelial cell interactions in anorexia nervosa. Eur J Clin Investig 2015;45:670\u20138.","key":"23160","DOI":"10.1111\/eci.12454"}],"container-title":["Dermatology Reports"],"original-title":[],"link":[{"URL":"https:\/\/www.pagepress.org\/journals\/dr\/article\/download\/10053\/9557","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.pagepress.org\/journals\/dr\/article\/download\/10053\/9738","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.pagepress.org\/journals\/dr\/article\/download\/10053\/9557","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,11]],"date-time":"2025-09-11T08:36:38Z","timestamp":1757579798000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.pagepress.org\/journals\/dr\/article\/view\/10053"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,1,20]]},"references-count":11,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2025,8,22]]}},"URL":"https:\/\/doi.org\/10.4081\/dr.2025.10053","relation":{},"ISSN":["2036-7406","2036-7392"],"issn-type":[{"type":"electronic","value":"2036-7406"},{"type":"print","value":"2036-7392"}],"subject":[],"published":{"date-parts":[[2025,1,20]]}}}