{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T18:51:55Z","timestamp":1791226315214,"version":"4.1.0"},"reference-count":6,"publisher":"PAGEPress Publications","issue":"3","license":[{"start":{"date-parts":[[2025,10,16]],"date-time":"2025-10-16T00:00:00Z","timestamp":1760572800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Dermatol Reports"],"abstract":"<jats:p>Psoriasiform eruptions are increasingly reported as adverse events during treatment of atopic dermatitis (AD) with interleukin (IL)-4\/IL-13 inhibitors, including dupilumab. These reactions may represent a possible overlap manifestation between AD and psoriasis (PSO), which are two conditions that, according to recent literature, could lie along a clinical spectrum and share certain clinical, pathogenetic, and histological features. We describe the case of a 30-year-old male with lifelong AD who developed psoriasiform plaques on his elbows and knees during dupilumab therapy. After discontinuation of dupilumab and initiation of upadacitinib 15 mg\/day, the patient achieved substantial improvement of both AD and psoriasiform eruptions at 6 months. This case highlights dupilumab-induced psoriasiform eruptions and underscores the therapeutic challenges associated with these clinical pictures. Upadacitinib appears to be a possible and effective treatment option for these presentations.<\/jats:p>","DOI":"10.4081\/dr.2025.10588","type":"journal-article","created":{"date-parts":[[2025,10,16]],"date-time":"2025-10-16T07:06:29Z","timestamp":1760598389000},"source":"Crossref","is-referenced-by-count":4,"title":["Psoriasiform eruption induced by dupilumab successfully treated with upadacitinib"],"prefix":"10.4081","volume":"18","author":[{"given":"Mattia","family":"Minghini","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Natale","family":"Schettini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lucrezia","family":"Pacetti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chiara","family":"Bocchi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alessandro","family":"Borghi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2549","published-online":{"date-parts":[[2025,10,16]]},"reference":[{"key":"33212","doi-asserted-by":"publisher","DOI":"10.1016\/j.xjidi.2021.100042"},{"key":"33213","doi-asserted-by":"publisher","DOI":"10.3390\/ijms23105518"},{"key":"33214","doi-asserted-by":"publisher","DOI":"10.1111\/dth.13142"},{"key":"33215","doi-asserted-by":"publisher","DOI":"10.1080\/09546634.2023.2258240"},{"key":"33216","doi-asserted-by":"publisher","DOI":"10.12788\/cutis.0858"},{"key":"33217","doi-asserted-by":"publisher","DOI":"10.1080\/09546634.2023.2183729"}],"container-title":["Dermatology Reports"],"original-title":[],"link":[{"URL":"https:\/\/journals.pagepress.net\/dr\/article\/download\/10588\/9779","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.pagepress.net\/dr\/article\/download\/10588\/10101","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.pagepress.net\/dr\/article\/download\/10588\/9779","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T18:01:47Z","timestamp":1791223307000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.pagepress.net\/dr\/article\/view\/10588"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,10,16]]},"references-count":6,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2026,9,1]]}},"URL":"https:\/\/doi.org\/10.4081\/dr.2025.10588","relation":{},"ISSN":["2036-7406","2036-7392"],"issn-type":[{"value":"2036-7406","type":"electronic"},{"value":"2036-7392","type":"print"}],"subject":[],"published":{"date-parts":[[2025,10,16]]}}}