{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,6]],"date-time":"2026-02-06T17:51:54Z","timestamp":1770400314102,"version":"3.49.0"},"reference-count":7,"publisher":"PAGEPress Publications","license":[{"start":{"date-parts":[[2026,2,6]],"date-time":"2026-02-06T00:00:00Z","timestamp":1770336000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Dermatol Reports"],"abstract":"<jats:p>Cutaneous smooth muscle hamartomas (SMHs) are benign proliferations of smooth muscle tissue, typically congenital and characterized by hyperpigmentation, hypertrichosis, and a positive pseudo- Darier\u2019s sign. We report an unusual case of an early-onset acquired SMH in a 49-year-old woman. The lesion first appeared during adolescence and remained asymptomatic and clinically inapparent except upon exposure to cold. Cold stimulation induced a transient, linear, wrinkled, hyperpigmented papular lesion on the left thigh, which resolved spontaneously within seconds after rewarming. Histological examination revealed dermal fibrosis and well-organized lobules of smooth muscle cells, confirming the diagnosis of SMH without requiring immunohistochemical analysis. This case highlights a unique and transient presentation of SMH revealed exclusively by cold exposure and reversible with rewarming. It broadens the clinical spectrum of SMHs and the importance of external stimuli in their diagnosis.<\/jats:p>","DOI":"10.4081\/dr.2026.10476","type":"journal-article","created":{"date-parts":[[2026,2,6]],"date-time":"2026-02-06T07:34:06Z","timestamp":1770363246000},"source":"Crossref","is-referenced-by-count":0,"title":["Cold-induced cutaneous smooth muscle hamartoma"],"prefix":"10.4081","author":[{"given":"Manuel","family":"Croix","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Catherine","family":"Szczurko","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arthur","family":"Joli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anne","family":"Dompmartin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C\u00e9cile","family":"Morice","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2549","published-online":{"date-parts":[[2026,2,6]]},"reference":[{"key":"35973","doi-asserted-by":"crossref","unstructured":"1. Charles A. Electron Microscopic Observations of the Arrector Pili Muscle of the Human Scalp*. J Invest Dermatol 1960;35:27\u201130.","DOI":"10.1038\/jid.1960.79"},{"key":"35974","doi-asserted-by":"crossref","unstructured":"2. Holst VA, Junkins-Hopkins JM, Elenitsas R. Cutaneous smooth muscle neoplasms: Clinical features, histologic findings, and treatment options. J Am Acad Dermatol 2002;46:477\u201194.","DOI":"10.1067\/mjd.2002.121358"},{"key":"35975","doi-asserted-by":"crossref","unstructured":"3. Fenot M, Leclair F, Poiraud C, Barbarot S. Un hamartome musculaire lisse qui va et vient... [Intermittent smooth muscle hamartoma]. Ann Dermatol Venereol 2016;143:872-4.","DOI":"10.1016\/j.annder.2016.05.005"},{"key":"35976","unstructured":"4. Garc\u00eda Muret MP, Puig L, Pujol RM, et al. Hamartome musculaire lisse non-cong\u00e9nital:3 cas. Ann Dermatol Venereol 2002;129:417-20."},{"key":"35977","doi-asserted-by":"crossref","unstructured":"5. Gagn\u00e9 EJ, Daniel Su WP. Congenital Smooth Muscle Hamartoma of the Skin. Pediatr Dermatol 1993;10:142\u20115.","DOI":"10.1111\/j.1525-1470.1993.tb00041.x"},{"key":"35978","doi-asserted-by":"crossref","unstructured":"6. Haydeh G, Massoud A, Pedram N. Multiple smooth muscle hamartoma: case report and review of the literature. Indian J Dermatol 2009;54:68-71.","DOI":"10.4103\/0019-5154.48993"},{"key":"35979","doi-asserted-by":"crossref","unstructured":"7. Kilitci A, Elmas \u00d6F. Cutaneous Smooth Muscle Tumors: A Clinicopathological Study Focusing on the Under-Recognized Histological Features. Turk Patoloji Derg 2020;36:126-34.","DOI":"10.5146\/tjpath.2019.01485"}],"container-title":["Dermatology Reports"],"original-title":[],"link":[{"URL":"https:\/\/journals.pagepress.net\/dr\/article\/download\/10476\/9865","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.pagepress.net\/dr\/article\/download\/10476\/9865","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,2,6]],"date-time":"2026-02-06T07:34:09Z","timestamp":1770363249000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.pagepress.net\/dr\/article\/view\/10476"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,2,6]]},"references-count":7,"URL":"https:\/\/doi.org\/10.4081\/dr.2026.10476","relation":{},"ISSN":["2036-7406","2036-7392"],"issn-type":[{"value":"2036-7406","type":"electronic"},{"value":"2036-7392","type":"print"}],"subject":[],"published":{"date-parts":[[2026,2,6]]}}}