{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T18:12:18Z","timestamp":1790100738796,"version":"4.0.1"},"reference-count":0,"publisher":"PAGEPress Publications","license":[{"start":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T00:00:00Z","timestamp":1790035200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Dermatol Reports"],"abstract":"<jats:p>Skindex-29 provides a domain-specific assessment of quality-of-life (QoL) burden in psoriasis, but real-world comparisons across treatment modalities and clinically relevant time points remain limited. We prospectively followed 183 adults with psoriasis (Psoriasis Area Severity Index [PASI]&gt;10) treated with phototherapy, conventional systemic agents, or biologics in a tertiary center. Skindex-29 total and domain scores were assessed at weeks 0, 4, 12, and 16. Total scores decreased significantly within all modalities (all p&lt;0.001), with earlier and larger observed reductions among patients receiving biologics. After Benjamini-Hochberg adjustment, between-group differences remained significant for total scores at weeks 0, 4, and 16; for Emotions and Functioning at weeks 0, 4, and 16; and for Symptoms at week 4. PASI was strongly correlated with all domains (r=0.692-0.795; all p&lt;0.001). Skindex-29 may complement PASI in domain-aware monitoring, although the non-randomized design precludes causal interpretation.<\/jats:p>","DOI":"10.4081\/dr.2026.10651","type":"journal-article","created":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T17:57:37Z","timestamp":1790099857000},"source":"Crossref","is-referenced-by-count":0,"title":["Domain-specific Skindex-29 response under biologics, conventional systemics, and phototherapy: a four-time-point real-world brief report"],"prefix":"10.4081","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6766-9196","authenticated-orcid":false,"given":"Ardea","family":"Milidrag","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-5762-4511","authenticated-orcid":false,"given":"Milena","family":"Zlatanovi\u0107","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0202-4837","authenticated-orcid":false,"given":"Vesna","family":"Mili\u010di\u0107","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7745-8333","authenticated-orcid":false,"given":"Gordana","family":"Risti\u0107","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6049-3586","authenticated-orcid":false,"given":"Kristina","family":"Andri\u0107","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9402-0832","authenticated-orcid":false,"given":"Ana","family":"Ravi\u0107-Nikoli\u0107","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2549","published-online":{"date-parts":[[2026,9,22]]},"container-title":["Dermatology Reports"],"original-title":[],"link":[{"URL":"https:\/\/journals.pagepress.net\/dr\/article\/download\/10651\/10012","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.pagepress.net\/dr\/article\/download\/10651\/10012","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T17:57:37Z","timestamp":1790099857000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.pagepress.net\/dr\/article\/view\/10651"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9,22]]},"references-count":0,"URL":"https:\/\/doi.org\/10.4081\/dr.2026.10651","relation":{},"ISSN":["2036-7406","2036-7392"],"issn-type":[{"value":"2036-7406","type":"electronic"},{"value":"2036-7392","type":"print"}],"subject":[],"published":{"date-parts":[[2026,9,22]]}}}